Nur 612 EXAM 2 pt 1 Questions with Correct Answers 100% Verified By Experts| Latest
Update Guaranteed Success
Acute phase proteins (APP) primarily produced in the liver and secreted into the blood in
response to inflammatory molecules (cytokines) from the immune system
CRP and MBL
compliment system Increase bacterial aggregation which leads to susceptibility of
phagocytosis
3 phases of the compliment system Initiation (activation)
Amplification (inflammation)
Membrane attack
adaptive immunity the ability to recognize and remember specific antigens and mount an
attack on them (has to distinguish between self and nonself)
Final line of defense
Activated once the innate immune system initiates the inflammatory response
Antigens Foreign material that invades the body
Leads to b-cell production
Bacteria, fungi, viruses, Protozoa, parasites, nonmicrobials, vaccines
Regulatory immune cells Control immune response
Effector immune response Accomplish final stages of immune response. Activated by T
lymph and other leukocytes
Lymphocytes Wbcs arise from bone marrow
,macrophages, dendritic cells -primarily cells of innate immunity but play a key role in
adaptive immunity
-function as antigen presenting cells (APCs)
Major Histocompatibility Complex (MHC) Important in allowing body to recognize self vs no
self
APCs (antigen presenting cells) engulf antigens and present fragments of antigens to T cells
for recognition
Bridge innate and adaptive immunity
HLA antigens Important in organ transplation
B cells (B lymphocytes) primary cell of antibody-mediated immunity, produce antibodies
that recognize antigens of pathogens—> become memory B cells or plasma cells
Produced in bone marrow
T cells (T lymphocytes) specialized white blood cells that receive markers in the thymus, are
responsible for cellular immunity, and assist with humoral immunity
humoral immunity specific immunity produced by B cells that produce antibodies that
circulate in body fluids
Helper T cells T cells that help the immune system by increasing the activity of killer cells
and stimulating the suppressor T cells
CD4 cells
Recruit and activate CD8
, Regulatory T cells moderate immune response
CD4 cells T helper cells
CD8 Self vs nonself recognition
Cytotoxic T cells Monitors activity and destroys threats
central lymphoid organs bone marrow & thymus
provide environment for immune cell production & maturation
Thymus An immune organ located near the heart. THe thymus is the site of T cell
maturation and is larger in children and adolescents. Storage for macrophages and dendritic
cells
lymph nodes Removal of foreign material before entering blood
Release antibodies
Drains into subclavian vein
Spleen Filters antigen, important in systemic infection
secondary lymphoid organ No encapsulated around membranes
Tonsils, appendix, pyer patches in intestines
Ig Produced by B cells that matured into plasma cells
Update Guaranteed Success
Acute phase proteins (APP) primarily produced in the liver and secreted into the blood in
response to inflammatory molecules (cytokines) from the immune system
CRP and MBL
compliment system Increase bacterial aggregation which leads to susceptibility of
phagocytosis
3 phases of the compliment system Initiation (activation)
Amplification (inflammation)
Membrane attack
adaptive immunity the ability to recognize and remember specific antigens and mount an
attack on them (has to distinguish between self and nonself)
Final line of defense
Activated once the innate immune system initiates the inflammatory response
Antigens Foreign material that invades the body
Leads to b-cell production
Bacteria, fungi, viruses, Protozoa, parasites, nonmicrobials, vaccines
Regulatory immune cells Control immune response
Effector immune response Accomplish final stages of immune response. Activated by T
lymph and other leukocytes
Lymphocytes Wbcs arise from bone marrow
,macrophages, dendritic cells -primarily cells of innate immunity but play a key role in
adaptive immunity
-function as antigen presenting cells (APCs)
Major Histocompatibility Complex (MHC) Important in allowing body to recognize self vs no
self
APCs (antigen presenting cells) engulf antigens and present fragments of antigens to T cells
for recognition
Bridge innate and adaptive immunity
HLA antigens Important in organ transplation
B cells (B lymphocytes) primary cell of antibody-mediated immunity, produce antibodies
that recognize antigens of pathogens—> become memory B cells or plasma cells
Produced in bone marrow
T cells (T lymphocytes) specialized white blood cells that receive markers in the thymus, are
responsible for cellular immunity, and assist with humoral immunity
humoral immunity specific immunity produced by B cells that produce antibodies that
circulate in body fluids
Helper T cells T cells that help the immune system by increasing the activity of killer cells
and stimulating the suppressor T cells
CD4 cells
Recruit and activate CD8
, Regulatory T cells moderate immune response
CD4 cells T helper cells
CD8 Self vs nonself recognition
Cytotoxic T cells Monitors activity and destroys threats
central lymphoid organs bone marrow & thymus
provide environment for immune cell production & maturation
Thymus An immune organ located near the heart. THe thymus is the site of T cell
maturation and is larger in children and adolescents. Storage for macrophages and dendritic
cells
lymph nodes Removal of foreign material before entering blood
Release antibodies
Drains into subclavian vein
Spleen Filters antigen, important in systemic infection
secondary lymphoid organ No encapsulated around membranes
Tonsils, appendix, pyer patches in intestines
Ig Produced by B cells that matured into plasma cells
