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ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM 2025 QUESTIONS AND ANSWERS

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ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM 2025 QUESTIONS AND ANSWERS

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2024/2025

Institution ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY

Course ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY

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Define neoadjuvant therapy - ANS Treatment is given prior to surgery to shrink the tumor Define adjuvant therapy - ANS Additional cancer treatment given after the primary treatment to lower the risk that the cancer reoccur 3 subcategories of alkylating agents: - ANS 1. Nitrogen mustards 2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as they work similarly) 3. Nitrosoureas Common alkylating agents: - ANS Cyclophosphamide (Cytoxan) Ifosfamide (Ifex) Bendamustine (Treanda) Common platinum-based agents: - ANS Cisplatin (Platinol) Carboplatin (Paraplatin) What is unique about nitrosoureas agents? - ANS Able to cross the blood-brain barrier; can be effective in treating some brain tumors ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM 2025 QUESTIONS AND ANSWERS Copyright ©2025 THEBRIGHT ALL RIGHTS RESERVED 2 Common nitrosoureas agents: - ANS Carmustine (BiCNU) Lomustine (CeeNu) Streptozocin (Zanosar) Hypersensitivity can occur with late doses of: - ANS Carboplatin These agents are typically categorized as highly emetogenic: - ANS 1. Alkylating agents 2. Nitrosoureas Pre-administration labs for alkylating agents and nitrosoureas: - ANS BUN Creatinine CBC w/ diff What is the medication Mesna used for? - ANS Bladder protectant with administration of cyclophosphamide or ifosfamide Instruct pts receiving ________ to avoid exposure to cold air and consuming cold fluids for 3-4 days following treatment - ANS Oxaliplatin How do antimetabolites function? - ANS By blocking DNA and RNA growth by interfering with enzymes needed for normal cell metabolism Antimetabolites work in the ___ phase. - ANS S Common side effects of antimetabolites: - ANS Myelosuppression GI toxicities Photosensit

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ONS CHEMOTHERAPY
IMMUNOTHERAPY CERTIFICATE
EXAM 2025 QUESTIONS AND ANSWERS

Define neoadjuvant therapy - ANS Treatment is given prior to surgery to shrink the tumor

Define adjuvant therapy - ANS Additional cancer treatment given after the primary
treatment to lower the risk that the cancer reoccur

3 subcategories of alkylating agents: - ANS 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as
they work similarly)
3. Nitrosoureas

Common alkylating agents: - ANS Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)

Common platinum-based agents: - ANS Cisplatin (Platinol)
Carboplatin (Paraplatin)

What is unique about nitrosoureas agents? - ANS Able to cross the blood-brain barrier; can
be effective in treating some brain tumors

Copyright ©2025 THEBRIGHT ALL RIGHTS RESERVED 1

,Common nitrosoureas agents: - ANS Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)

Hypersensitivity can occur with late doses of: - ANS Carboplatin

These agents are typically categorized as highly emetogenic: - ANS 1. Alkylating agents
2. Nitrosoureas

Pre-administration labs for alkylating agents and nitrosoureas: - ANS BUN
Creatinine
CBC w/ diff

What is the medication Mesna used for? - ANS Bladder protectant with administration of
cyclophosphamide or ifosfamide

Instruct pts receiving ________ to avoid exposure to cold air and consuming cold fluids for 3-4
days following treatment - ANS Oxaliplatin

How do antimetabolites function? - ANS By blocking DNA and RNA growth by interfering
with enzymes needed for normal cell metabolism

Antimetabolites work in the ___ phase. - ANS S

Common side effects of antimetabolites: - ANS Myelosuppression
GI toxicities
Photosensitivity

Copyright ©2025 THEBRIGHT ALL RIGHTS RESERVED 2

, Hand-foot syndrome

Common antimetabolite drugs: - ANS Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate

The institute for Safe Medication Practices recommends what route of administration for
vincristine? - ANS IV piggyback via gravity

Anthracycline antitumor abx work by: - ANS Interfering with enzymes necessary for DNA to
replicate in ALL phases of the cell cycle

The two major classifications of antitumor antibiotics are: - ANS Anthracyclines
Non-anthracyclines

Common anthracycline antitumor abx: - ANS Daunorubicin
Doxorubicin
Epirubicin
Idarubicin

The antitumor abx ___________ is not an anthracycline, but has anthracycline-type properties.
- ANS Mitoxantrone

Common non-anthracycline antitumor abx: - ANS Actinomycin D
Mitomycin C
Copyright ©2025 THEBRIGHT ALL RIGHTS RESERVED 3

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Uploaded on: July 8, 2025
Number of pages: 18
Written in: 2024/2025
Type: Exam (elaborations)
Contains: Questions & answers

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