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Summary Vaccines – Complete Notes for NCLEX-RN (NCSBN) Nursing Students | Types, Schedules, Mechanisms & More (1st Year PDF)

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This PDF contains detailed and well-organized notes on Vaccines, specially curated for NCLEX- RN (NCSBN),BSc Nursing 1st Year students. These notes are based on the standard nursing curriculum and cover all essential concepts related to types of vaccines, mechanism of action, immunization schedules, cold chain management, and more. Designed in simple language with bullet points, charts, and diagrams, these notes help students prepare for theory exams, practicals, viva, and assignments with ease.Topics Covered: Introduction to Vaccines Types of Vaccines (Live, Killed, Toxoids, etc.) Active vs Passive Immunity National Immunization Schedule (India-based) WHO Recommended Vaccines Route of Administration Vaccine Storage & Cold Chain Adverse Events Following Immunization (AEFI) COVID-19 Vaccines (Overview)

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What is a “Vaccine”
 The term vaccine derives
from Edward Jenner's
1796 use of the term cow
pox (Latin) variola vaccinæ,
adapted from the Latin
vaccīn-us, from vacca cow),
which, when administered
to humans, provided them
protection against
smallpox

, Milestones in vaccine development
1798: Edward Jenner invented
smallpox vaccine


1885: Louis Pasteur developed the first vaccine to
protect humans against rabies


1927: BCG vaccine recognized


1955: Dr. Jonas Salk’s inactivated polio vaccine licensed,
beginning the decline of polio worldwide.

, Milestones in vaccine development
1963 : Dr. Albert Sabin introduced trivalent oral polio vaccine The
first measles vaccine licensed

1971 : The MMR vaccine licensed.

1982 : Hepatitis B vaccine becomes available.
Blumberg & Millman Irwing

1995 : Varicella vaccine is licensed. Hepatitis A
vaccine licensed. Acellular pertussis
vaccine licensed

, Milestones in vaccine development

2003: The first live attenuated influenza vaccine(FLUMIST) licensed
for use in people from 5 to 49 years of age.


2005: FDA licenses the meningococcal conjugate vaccine to
prevent invasive meningococcal diseases (MENATRA)

2006: FDA licenses the HPV (GARDASIL) and Rotavirus vaccines (Rota
Teq)

2008: Two dose rotavirus vaccine (ROTARIX) approved
2009: Influenza A (H1N1) vaccine approved

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July 8, 2025
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