Nagelhout Pharmacology Exam 1 |\ |\ |\ |\
Review questions with answers |\ |\ |\
Pharmacology - CORRECT ANSWERS ✔✔the study of the effect of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chemicals on living tissue
|\ |\ |\
Pharmacokinetics - CORRECT ANSWERS ✔✔the study of the |\ |\ |\ |\ |\ |\ |\ |\
absorption, distribution, metabolism and excretion of drugs
|\ |\ |\ |\ |\ |\
Pharmaceutics - CORRECT ANSWERS ✔✔the formulation and |\ |\ |\ |\ |\ |\ |\
preparation of drugs |\ |\
pharmacoeconomics - CORRECT ANSWERS ✔✔the study of the |\ |\ |\ |\ |\ |\ |\ |\
economic impact of drugs
|\ |\ |\
toxicology - CORRECT ANSWERS ✔✔the study of the harmful
|\ |\ |\ |\ |\ |\ |\ |\ |\
effects of chemicals
|\ |\
pharmacognosy - CORRECT ANSWERS ✔✔the study of the |\ |\ |\ |\ |\ |\ |\ |\
medicinal uses of naturally occurring compounds
|\ |\ |\ |\ |\
pharmacy - CORRECT ANSWERS ✔✔the preparation and
|\ |\ |\ |\ |\ |\ |\
dispensing of drugs |\ |\
pharmacogenetics - CORRECT ANSWERS ✔✔genetic influences by |\ |\ |\ |\ |\ |\
and on drugs
|\ |\ |\
,pharmacodynamics - CORRECT ANSWERS ✔✔physiological and |\ |\ |\ |\ |\ |\
biochemical mechanism of action of drugs
|\ |\ |\ |\ |\
(e.g. receptor theory)
|\ |\
pharmacogenomics - CORRECT ANSWERS ✔✔identifies discrete |\ |\ |\ |\ |\ |\
genetic differences among individuals that play a critical role in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
drug response
|\
pharmacoepidemiology - CORRECT ANSWERS ✔✔is the study of |\ |\ |\ |\ |\ |\ |\ |\
the use and effects of drugs on large groups of people
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ED50 - CORRECT ANSWERS ✔✔Effective dose in 50% of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
population
TD50 - CORRECT ANSWERS ✔✔Toxic Dose in 50% of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
population
LD50 - CORRECT ANSWERS ✔✔Lethal Dose in 50% of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
population
Therapeutic index - CORRECT ANSWERS ✔✔LD50/ED50
|\ |\ |\ |\ |\
Therapeutic window - CORRECT ANSWERS ✔✔TD50/ED50
|\ |\ |\ |\ |\
Two types of ligands - CORRECT ANSWERS ✔✔Agonist or
|\ |\ |\ |\ |\ |\ |\ |\ |\
Antagonist
, Reversible binding of ligands is called - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\ |\
✔✔competitive
non-reversible binding of ligands is called - CORRECT ANSWERS |\ |\ |\ |\ |\ |\ |\ |\ |\
✔✔noncompetitive
5 types of chemical bonds in order of increasing strength -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔van der waals, hydrophobic, hydrogen,
|\ |\ |\ |\ |\ |\ |\
ionic, covalent |\
5 types of chemical bonds in order of decreasing strength -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔covalent, ionic, hydrogen, hydrophobic,
|\ |\ |\ |\ |\ |\
van der waals
|\ |\
Occupation of receptors by ligands is governed by: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔affinity |\
Activation of receptors by ligands is governed by: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔efficacy |\
A dose response curve can show: - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\ |\
✔✔Affinity (potency), Efficacy, Variability, Slope
|\ |\ |\ |\
Up regulation - CORRECT ANSWERS ✔✔an increase in receptor
|\ |\ |\ |\ |\ |\ |\ |\ |\
proteins as a response to chronic blockade
|\ |\ |\ |\ |\ |\
Review questions with answers |\ |\ |\
Pharmacology - CORRECT ANSWERS ✔✔the study of the effect of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
chemicals on living tissue
|\ |\ |\
Pharmacokinetics - CORRECT ANSWERS ✔✔the study of the |\ |\ |\ |\ |\ |\ |\ |\
absorption, distribution, metabolism and excretion of drugs
|\ |\ |\ |\ |\ |\
Pharmaceutics - CORRECT ANSWERS ✔✔the formulation and |\ |\ |\ |\ |\ |\ |\
preparation of drugs |\ |\
pharmacoeconomics - CORRECT ANSWERS ✔✔the study of the |\ |\ |\ |\ |\ |\ |\ |\
economic impact of drugs
|\ |\ |\
toxicology - CORRECT ANSWERS ✔✔the study of the harmful
|\ |\ |\ |\ |\ |\ |\ |\ |\
effects of chemicals
|\ |\
pharmacognosy - CORRECT ANSWERS ✔✔the study of the |\ |\ |\ |\ |\ |\ |\ |\
medicinal uses of naturally occurring compounds
|\ |\ |\ |\ |\
pharmacy - CORRECT ANSWERS ✔✔the preparation and
|\ |\ |\ |\ |\ |\ |\
dispensing of drugs |\ |\
pharmacogenetics - CORRECT ANSWERS ✔✔genetic influences by |\ |\ |\ |\ |\ |\
and on drugs
|\ |\ |\
,pharmacodynamics - CORRECT ANSWERS ✔✔physiological and |\ |\ |\ |\ |\ |\
biochemical mechanism of action of drugs
|\ |\ |\ |\ |\
(e.g. receptor theory)
|\ |\
pharmacogenomics - CORRECT ANSWERS ✔✔identifies discrete |\ |\ |\ |\ |\ |\
genetic differences among individuals that play a critical role in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
drug response
|\
pharmacoepidemiology - CORRECT ANSWERS ✔✔is the study of |\ |\ |\ |\ |\ |\ |\ |\
the use and effects of drugs on large groups of people
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ED50 - CORRECT ANSWERS ✔✔Effective dose in 50% of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
population
TD50 - CORRECT ANSWERS ✔✔Toxic Dose in 50% of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
population
LD50 - CORRECT ANSWERS ✔✔Lethal Dose in 50% of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
population
Therapeutic index - CORRECT ANSWERS ✔✔LD50/ED50
|\ |\ |\ |\ |\
Therapeutic window - CORRECT ANSWERS ✔✔TD50/ED50
|\ |\ |\ |\ |\
Two types of ligands - CORRECT ANSWERS ✔✔Agonist or
|\ |\ |\ |\ |\ |\ |\ |\ |\
Antagonist
, Reversible binding of ligands is called - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\ |\
✔✔competitive
non-reversible binding of ligands is called - CORRECT ANSWERS |\ |\ |\ |\ |\ |\ |\ |\ |\
✔✔noncompetitive
5 types of chemical bonds in order of increasing strength -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔van der waals, hydrophobic, hydrogen,
|\ |\ |\ |\ |\ |\ |\
ionic, covalent |\
5 types of chemical bonds in order of decreasing strength -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔covalent, ionic, hydrogen, hydrophobic,
|\ |\ |\ |\ |\ |\
van der waals
|\ |\
Occupation of receptors by ligands is governed by: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔affinity |\
Activation of receptors by ligands is governed by: - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔efficacy |\
A dose response curve can show: - CORRECT ANSWERS
|\ |\ |\ |\ |\ |\ |\ |\ |\
✔✔Affinity (potency), Efficacy, Variability, Slope
|\ |\ |\ |\
Up regulation - CORRECT ANSWERS ✔✔an increase in receptor
|\ |\ |\ |\ |\ |\ |\ |\ |\
proteins as a response to chronic blockade
|\ |\ |\ |\ |\ |\
