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Exam (elaborations)

NR 508 Pharm Week 3 Chamberlain latest updated exam with expert solutions + Rationales

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NR 508 Pharm Week 3 Chamberlain latest updated exam with expert solutions + Rationales

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NR 508 Pharm Week 3 Chamberlain latest updated

exam with expert solutions + Rationales



1. Angiotensin-converting-enzyme (ACE) inhibitors are a central

part of the treatment of heart failure because they have more

than one action to address the pathological changes in this



,disorder. Which of the following pathological changes in heart

failure is NOT addressed by ACE inhibitors?

1. Changes in the structure of the left ventricle so that it

dilates, hypertro- phies, and uses energy less efficiently.

2. Reduced formation of cross-bridges so that contractile force

decreases.

3. Activation of the sympathetic nervous system that

increases heart rate and preload.

4. Decreased renal blood flow that decreases oxygen supply to

the kidneys.-

: 3. Activation of the sympathetic nervous system that increases heart

rate and preload.




2. One of the three types of heart failure involves systolic

dysfunction. Po- tential causes of this most common form of

heart failure include:




,1. Myocardial ischemia and injury secondary to myocardial

infarction

2. Inadequate relaxation and loss of muscle fiber secondary

to valvular dysfunction

3. Increased demands of the heart beyond its ability to adapt

secondary to anemia

4. Slower filling rate and elevated systolic pressures secondary

to uncon- trolled hypertension: 1. Myocardial ischemia and injury

secondary to myocardial infarction




3. The American Heart Association and the American College of

Cardiology have devised a classification system for heart

failure that can be used to direct treatment. Patients with

symptoms and underlying disease are classi- fied as stage:

1. A

2. B




, 3. C

4. D: 3. C




5. Diagnosis of heart failure cannot be made by symptoms

alone because many disorders share the same symptoms. The

most specific and sensitive diagnostic test for heart failure is:

1. Chest x-rays that show cephalization and measure heart

size

2. Two-dimensional echocardiograms that identify structural

anomalies and cardiac dysfunction

3. Complete blood count, blood urea nitrogen, and serum

electrolytes that facilitate staging for end-organ damage

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