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Test Bank For Cellular and Molecular Immunology, 10th Edition (Abbas, 2022), Chapter 1-21, All Chapters ||Complete A+ Guide

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Test Bank For Cellular and Molecular Immunology, 10th Edition (Abbas, 2022), Chapter 1-21, All Chapters ||Complete A+ Guide

Institution
Cellular And Molecular Immunology, 10th Edition
Course
Cellular And Molecular Immunology, 10th Edition











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Institution
Cellular And Molecular Immunology, 10th Edition
Course
Cellular And Molecular Immunology, 10th Edition

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Uploaded on
July 4, 2025
Number of pages
110
Written in
2024/2025
Type
Exam (elaborations)
Contains
Questions & answers

Subjects

  • 10th edition

Content preview

TEST BANK yy




Cellular and Molecular Immunology
yy yy yy




Abul Abbas, Andrew Lichtman, and Shiv Pillai
yy yy yy yy yy yy




10th Edition
yy

,Table of Contents
yy yy




Chapter 01 Properties and Overview of Immune Responses
yy y y yy y y y y yy y y 1
Chapter 02 Cells and Tissues of the Immune System
yy y y yy y y y y y y yy y y 3
Chapter 03 Leukocyte Circulation and Migration Into Tissues
yy y y y y y y y y y y y y 6
Chapter 04 Innate Immunity
yy y y y y 10
Chapter 05 Antibodies and Antigens
y y y y yy y y 17
Chapter 06 Antigen Presentation to T Lymphocytes and the Functions of Major
yy y y y y y y y y y y y y y y y y yy y y




Histocompatibility Complex Molecules
y y y y 20
Chapter 07 Immune Receptors and Signal Transduction
yy y y yy y y yy y y 27
Chapter 08 Lymphocyte Development and Antigen Receptor Gene Rearrangement
yy yy yy y y y y y y y y y y 30
Chapter 09 Activation of T Lymphocytes
y y y y y y y y y y 34
Chapter yy 10 y y Differentiation and Functions of CD4+ Effector T Cells y y y y yy y y y y y y y y 38
Chapter yy 11 y y Differentiation and Functions of CD8+ Effector T Cells y y y y yy y y y y y y y y 42
Chapter y y 12 y y B Cell Activation and Antibody Production
y y y y y y y y y y 46
Chapter yy 13 y y Effector Mechanisms of Humoral Immunity
y y yy y y y y 52
Chapter yy 14 yy Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
y y y y yy y y y y y y y y yy y y 56
Chapter yy 15 yy Immunologic Tolerance and Autoimmunity yy yy y y 62
Chapter y y 16 y y Immunity to Microbes y y y y 67
Chapter y y 17 y y Transplantation Immunology y y 72
Chapter y y 18 y y Tumor Immunology y y 77
Chapter y y 19 y y Hypersensitivity Disorders y y 81
Chapter y y 20 y y Allergy 86
Chapter y y 21 y y Primary and Acquired Immunodeficiencies
y y y y y y 89

,Chapter 01: Properties and Overview of Immune Responses
yy yy yy yy yy yy yy




Abbas, Lichtman, and Pillai: Cellular and Molecular Immunology, 10th Edition
yy yy yy yy yy yy yy yy yy




MULTIPLE CHOICE yy




1. The principal function of the immune system is:
yy yy yy yy yy yy yy



a. Defense against cancer yy yy



b. Repair of injured tissues yy yy yy



c. Defense against microbial infections yy yy yy



d. Prevention of inflammatory diseases yy yy yy



e. Protection against environmental toxins yy yy yy




ANS: C
The immune system has evolved in the setting of selective pressures imposed
y y y y y y y y y y y y y y y y y y y y y y



by microbial infections. Although immune responses to cancer may occur, the
y y yy y y y y y y y y y y y y y y yy y y



concept that ―immunosurveillance‖ against cancer is a principal function of the immune
yy y y yy yy y y yy yy yy yy y y yy yy



system is controversial. Repair of injured tissues may be a secondary
yy y y yy y y y y y y y y y y y y y y y y



consequence of the immune responses and inflammation. Although the immune
y y y y y y y y yy yy yy y y yy yy



system has regulatory features that are needed to prevent excessive inflammation,
yy y y yy yy yy yy y y y y y y y y y y



prevention of inflammatory diseases is not a
y y y y y y y y y y y y y y



primary function. The immune system can protect against microbial toxins, but it generally
yy yy yy yy yy yy yy yy yy yy yy yy



does not offer protection against toxins of nonbiologic origin.
y y y y y y y y y y y y y y y y y y




2. Which of the following infectious diseases was prevented by the first
yy yy yy yy yy yy yy yy yy yy



successful vaccination?
y y yy



a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
ANS: C
In 1798, Edward Jenner reported the first intentional successful vaccination,
y y y y y y yy y y y y y y y y y y



which was against smallpox in a boy, using material from the cowpox pustules
y y y y yy y y y y yy yy yy y y y y yy y y y y



of a milkmaid. In 1980, smallpox was reported to be eradicated worldwide by
yy yy yy yy yy y y y y y y y y y y y y y y y y



a vaccination program.
y y y y y y



Effective vaccines against tetanus toxin, rubella virus, and poliovirus were
y y y y y y y y yy y y y y y y y y



developed in the 20th century and are widely used. There is no effective
yy yy y y y y y y y y y y y y y y y y y y y y y y



vaccine against Mycobacterium tuberculosis.
y y y y yy yy




3. Which of the following is a unique property of the adaptive immune system?
yy yy yy yy yy yy yy yy yy yy yy yy



a. Highly diverse repertoire of specificities for antigens yy yy yy yy yy yy



b. Self-nonself discrimination yy



c. Recognition of microbial structures by both cell-associated and soluble receptors yy yy yy yy yy yy yy yy yy



d. Protection against viral infections yy yy yy



e. Responses that have the same kinetics and magnitude on repeated exposure to yy yy yy yy yy yy yy yy yy yy yy



the same microbe y y yy yy




ANS: A

, Highly diverse repertoires of specificities for antigens are found only in T
y y y y y y y y y y y y y y y y y y y y y y



and B lymphocytes, which are the central cellular components of the
y y y y yy y y y y y y y y y y y y y y y y



adaptive immune system. Both the innate and the adaptive immune systems
y y y y yy y y y y y y y y y y y y y y y y



use cell-associated and soluble receptors to recognize microbes, display some degree
y y y y y y yy yy yy yy yy yy yy yy



of self-nonself discrimination, and protect against viruses. On repeated exposure
yy yy y y y y y y y y y y y y y y y y



to the same microbe, the adaptive immune response becomes more rapid and
yy y y yy yy yy y y y y y y y y y y y y y y



of greater magnitude; this is the manifestation of memory.
y y y y y y y y y y yy yy yy yy




4. Antibodies and T lymphocytes are the respective mediators of which two types
yy yy yy yy yy yy yy yy yy yy yy



y of immunity?
y yy



a. Innate and adaptive yy yy



b. Passive and active yy yy



c. Specific and nonspecific yy yy



d. Humoral and cell-mediated yy yy



e. Adult and neonatal yy yy




ANS: D
Both B and T lymphocytes are principal components of adaptive immunity. B
y y yy y y yy y y yy y y y y y y y y y y



lymphocytes produce antibodies, which are the recognition and effector molecules of
yy yy yy yy yy yy yy yy yy yy yy



y humoral immune responses to extracellular pathogens. T cells recognize and promote
y yy yy yy yy yy yy yy yy yy yy



y eradication of intracellular pathogens in cell-mediated immunity. Passive and active
y yy yy yy yy yy yy yy yy yy



immunity both can be mediated by either B or T lymphocytes. Specific
yy y y y y y y y y y y y y y y y y y y y y y y



immunity is another term for adaptive immunity. Both B and T
y y y y yy y y y y y y y y y y y y y y y y



lymphocytes participate in adult adaptive immunity but are still developing
y y y y y y y y yy y y y y y y y y y y



in the neonatal period.
y y y y y y y y




5. The two major functional classes of effector T lymphocytes are:
yy yy yy yy yy yy yy yy yy



a. Helper T lymphocytes and cytotoxic T lymphocytes yy yy yy yy yy yy




b. Natural killer cells and cytoWtoWxW
ic.TTlB
yS
mMph.oW
cyStes yy yy yy yy



c. Memory T cells and effector T cells yy yy yy y y yy yy



d. Helper cells and antigen-presenting cells yy yy yy yy



e. Cytotoxic T lymphocytes and target cells yy yy yy yy yy




ANS: A
T cells can be classified into effector subsets that perform different effector functions.
yy yy yy yy yy yy yy yy yy yy yy yy



y Most effector T cells are either helper T lymphocytes, which enhance the
y y y y y y y y y y y y y y y y y y y y y y y



responses of other immune cells, including phagocytes and B cells, to
y y y y yy y y y y y y y y y y y y y y y y



infections, or cytotoxic T lymphocytes, which directly kill infected cells.
y y y y y y y y yy y y y y y y y y y y



Natural killer cells are not T lymphocytes.
y y y y y y y y y y y y yy



Antigen-presenting cells usually are not T cells. Memory T cells are not effector T yy yy yy yy yy yy yy yy yy yy yy yy yy



cells.
yy




6. Which of the following cell types is required for all adaptive humoral immune
yy yy yy yy yy yy yy yy yy yy yy yy



responses?
yy



a. Natural killer cells yy yy



b. Dendritic cells yy



c. Cytolytic T lymphocytes yy yy



d. B lymphocytes y y



e. Helper T lymphocytes yy yy




ANS: D
Humoral immune responses are antibody-mediated immune responses, and all antibodies
yy yy yy yy yy yy yy yy yy



are made by B lymphocytes and no other cell type.
yy y y y y y y y y y y y y y y y y y y

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