ZOO 3603C - Exam 3 Practice Questions And Correct Answers.

ZOO 3603C - Exam 3 Practice Questions And Correct
Answers.



Limb Dev I: Name the parts of the limb - Stylopod: humerus, femur
Zeugopod: ulna + radius, tibia + fibula
Autopod: wrist + fingers, ankle + toes


Limb Dev I: what tissue does the limb bud emerge from? - the flank lateral
plate mesoderm
(upper LPM)


Limb Dev I: what does the somite position of the limb bud determine? - neck
length


Limb Dev I: where does the limb bud appear in every animal? - at the same Hox
position
border of c5 and c6


Limb Dev I: what is the limb bud composed of? - epithelium covering
two types of mesenchymal cells


Limb Dev I: what are the two types of mesenchymal cells that the limb bud is
composed of? - Lateral plate mesenchyme
somitic cells




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, Limb Dev I: what do the somitic cells make in the limb bud? - myoblasts of the
limbs, muscle fibers
NOT connective tissues


Limb Dev I: what happens in the limb bud/adult limb if you remove somite? -
no muscle or muscle fibers


Limb Dev I: what is the gene that shows evidence for somitic migration into the
limb bud? - Pax 3


Limb Dev I: what is the receptor for Pax 3? - c-met


Limb Dev I: what is the ligand for c-met? - HGF
expressed in distal limb bud


Limb Dev I: what are splotch mice? - they have no limb muscles, because no
migration of somitic cells into the limb because no Pax3


Limb Dev I: what is the role of Lbx in the limb bud? - involved in production of
extensors and flexors. Without Lbx, extensors and flexors are reduced


Limb Dev I: what sculpts the limb? - cell death


Limb Dev I: what induces cell death that separates digits in the developing limb
bud? - BMP4


Limb Dev I: what is the progress zone responsible for? - outgrowth




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