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NR 607 Pharmacology Midterm exam with correct answers.

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NR 607 Pharmacology Midterm exam with correct answers.

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NR 607 Pharmacology Midterm exam with
correct answers

Adsorption |- |✔✔occurs |when |one |agent |binds |the |other |to |its |surface |to |form |a |complex

Absorption |- |✔✔process |that |occurs |from |the |time |a |drug |enters |the |body |to |the |time |it |enters |the |
bloodstream |to |be |circulated

Bioavailability |- |✔✔Is |the |portion |of |a |dose |that |reaches |the |systemic |circulation |and |is |available |to |
act |on |body |cells

Distribution |- |✔✔Involves |the |transport |of |drug |molecules |within |the |body

An |important |factor |in |distribution |is: |- |✔✔Protein |binding

What |two |ways |allows |drugs |to |enter |the |blood |brain |barrier? |- |✔✔Drugs |must |be |lipid |soluble |or |

Have |a |transport |system |that |can |cross |the |blood-brain |barrier |and |reach |therapeutic |concentrations |
in |brain |tissue

What |is |a |common |carrier |for |drugs |in |the |body? |- |✔✔plasma |proteins |(mainly |albumin)

What |part |of |the |drug |acts |on |body |cells? |- |✔✔The |free |or |unbound |portion |of |the |drug

What |happens |to |bound |drug |when |plasma |drug |levels |decrease? |- |✔✔Some |of |the |bound |drug |is |
released

What |allows |a |part |of |a |drug |dose |to |be |stored |and |released |as |needed? |- |✔✔Protein |binding

Conditions |that |may |decrease |plasma |albumin |levels |- |✔✔Liver |Disease

Inflammatory |Disease

Malnutrition

Burns/Bone |Fx

Acute |Infection

Renal |Disease

Conditions |that |may |increase |plasma |albumin |levels |- |✔✔Myalgia

Surgical |Procedures

Gynecological |Disorders

Benign |Tumors

Two |pathways |of |drug |excretion |- |✔✔Main: |via |the |kidneys

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