NURS 8024 Pharm Exam 3 (antimicrobial part 2) 2025 COMPLETE
NURS 8024 Pharm Exam 3 (antimicrobial part 2)
QUESTIONS With 100% Verified Solutions,
Study online at https://quizlet.com/_foa3tn
1. Bacterial protein Clindamycin
synthesis inhibitors
2. Clindamycin Time dependent killing
Inhibits protein synthesis
Bacteriostatic
90% bioavailability
3. Clindamycin mech- Altered target sites
anism of resistance Active efflux (pushes drug out of the cell)
4. Clindamycin ADE GI upset
Skin rash
Neutropenia
Superinfections such a c diff pseudomembranous
- don't use if patient has history of c diff
5. Clindamycin indica- Gram positive
tions Prophylaxis of endocarditis in valve patients with PCN allergy
6. Oxazolidinones New class of bacterial protein synthesis inhibitors
Time dependent killing
Prevents formation of ribosome complex
Bacteriostatic & Bactericidal against strep
7. Linezolid Protein synthesis inhibitor
100% bioavailability orally
30% CSF penetration
8. Linezolid ADE Hematologic
Increased thrombocytopenia risk
Anemia, neutropenia, neuropathy
1/8
, NURS 8024 Pharm Exam 3 (antimicrobial part 2)
Study online at https://quizlet.com/_foa3tn
Optic & peripheral neuropathy
Serotonin syndrome with SSRIs
9. Linezolid Indica- Gram positive resistant
tions VRE, HCAP, CAP
Complicated skin & tissue infections
Off label use for TB
No resistance currently
10. Fluoroquinolones Norfloxacin (1st gen)
Ciprofloxacin & Ofloxacin (2nd gen)
Levofloxacin (3rd gen)
Moxifloxacin & Gemifloxacin (3rd gen respiratory)
11. Fluoroquinolones Generations according to antimicrobial spectra
are classified by
12. 1st Generation Flu- Narrow gram negative
oroquinolone Norfloxacin
13. 2nd Generation Flu- Broad- gram negative and gram positive
oroquinolone Cipro & ofloxacin
14. 3rd generation Flu- More gram positive than gram negative
oroquinolone Levofloxacin
Moxifloxacin
Gemifloxacin
-moxi and gemi are respiratory Fluoroquinolones
15. Fluoroquinolones Inhibits DNA synthesis
MOA Bactericidal
Concentration dependent killing
2/8
NURS 8024 Pharm Exam 3 (antimicrobial part 2)
QUESTIONS With 100% Verified Solutions,
Study online at https://quizlet.com/_foa3tn
1. Bacterial protein Clindamycin
synthesis inhibitors
2. Clindamycin Time dependent killing
Inhibits protein synthesis
Bacteriostatic
90% bioavailability
3. Clindamycin mech- Altered target sites
anism of resistance Active efflux (pushes drug out of the cell)
4. Clindamycin ADE GI upset
Skin rash
Neutropenia
Superinfections such a c diff pseudomembranous
- don't use if patient has history of c diff
5. Clindamycin indica- Gram positive
tions Prophylaxis of endocarditis in valve patients with PCN allergy
6. Oxazolidinones New class of bacterial protein synthesis inhibitors
Time dependent killing
Prevents formation of ribosome complex
Bacteriostatic & Bactericidal against strep
7. Linezolid Protein synthesis inhibitor
100% bioavailability orally
30% CSF penetration
8. Linezolid ADE Hematologic
Increased thrombocytopenia risk
Anemia, neutropenia, neuropathy
1/8
, NURS 8024 Pharm Exam 3 (antimicrobial part 2)
Study online at https://quizlet.com/_foa3tn
Optic & peripheral neuropathy
Serotonin syndrome with SSRIs
9. Linezolid Indica- Gram positive resistant
tions VRE, HCAP, CAP
Complicated skin & tissue infections
Off label use for TB
No resistance currently
10. Fluoroquinolones Norfloxacin (1st gen)
Ciprofloxacin & Ofloxacin (2nd gen)
Levofloxacin (3rd gen)
Moxifloxacin & Gemifloxacin (3rd gen respiratory)
11. Fluoroquinolones Generations according to antimicrobial spectra
are classified by
12. 1st Generation Flu- Narrow gram negative
oroquinolone Norfloxacin
13. 2nd Generation Flu- Broad- gram negative and gram positive
oroquinolone Cipro & ofloxacin
14. 3rd generation Flu- More gram positive than gram negative
oroquinolone Levofloxacin
Moxifloxacin
Gemifloxacin
-moxi and gemi are respiratory Fluoroquinolones
15. Fluoroquinolones Inhibits DNA synthesis
MOA Bactericidal
Concentration dependent killing
2/8
