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2025
Escitalopram may cause serious, potentially fatal reactions when used with _______________.
(select all that apply) - correct answers-Duloxetine, amitriptilyne, sertraline, St. John's Wort
Mixing two serotonin agents can cause serotonin syndrome.
The therapeutic effects of imipramine develop over _____________. - correct answers-Several
weeks
The FDA-approved indications for fluoxetine include: (select all that apply) - correct answers-
Obsessive compulsive disorder, major depressive disorder, bulimia nervosa
,Taking food with buspirone alters absorption. - correct answers-False
May be taken with food to minimize gastric irritation
Venlafaxine is extensively metabolized on first pass through the ___________. - correct
answers-Liver
Signs and symptoms of lithium toxicity include: (select all that apply) - correct answers-Slurred
speech, drowsiness
Valproate acid has FDA-approved indications for: (select all that apply) - correct answers-Acute
mania, simple and complex absence seizures, prevention of migraine headaches
Atomoxetine selectively ____________ the presynaptic reuptake of norepinephrine resulting in
a(n) ________________ attention span. - correct answers-Inhibits, improved
Phenelzine does not need to be discontinued several days before elective surgery that requires
anesthesia. - correct answers-False
Bupropion can be used for smoking cessation. - correct answers-True
Methylphenidate is not effective for narcoleptic patients. - correct answers-False
,Clozapine may cause: (select all that apply) - correct answers-Syncope, orthostatic hypotension,
cardiac arrest
Causes bradycardia which could lead to syncope and cardiac arrest
Administering risperidone with levodopa is contraindicated. - correct answers-True
It decreases the effects of levodopa
The ___________ form of ziprasidone is frequently used for control of acutely agitated patients.
- correct answers-Intramuscular (IM)
Anticonvulsants are frequently used as mood stabilizers for the treatment of mania and bipolar
spectrum disorders because they: - correct answers-Reduce synaptic kindling
A patient was started on fluoxetine for depression 3 days ago. She now complains that it
"doesn't help" and refuses to take it. Understanding the psychopharmacology, the nurse's best
first action is to: - correct answers-Discuss with the patient that these types of medications
often take several weeks before seeing the results.
Which of the following is a common side effect of both first- and second-generation
antipsychotic drugs? (select all that apply) - correct answers-Extrapyramidal side effects such as
pseudo-parkinsonism or acute dystonia, neuroleptic malignant syndrome, excessive sedation
, A male patient who is taking the second-generation antipsychotic reports to the nurse that he
has observed a clear fluid leaking from his right nipple for the past month. The nurse's best
initial intervention is: - correct answers-Inform the patient that this could be a side effect of the
medication
The physician discusses the appropriateness of prescribing a serotonin/norepinephrine
reuptake inhibitor (SNRI) for a patient. Which of the following medications are in this category?
- correct answers-Venlafaxine and duloxetine
A patient has been prescribed a selective serotonin reuptake inhibitor (SSRI) for depression. The
nurse should counsel the patient about which of the following possible side effects, among
others? - correct answers-Fever, sweating, agitation, rapid heartbeat
A nurse counsels a patient who has been prescribed a monoamine oxidase inhibitor (MAOI) to
treat depression to avoid foods containing tyramine. Which of the following foods should the
patient avoid? (select all that apply) - correct answers-Yogurt, tofu, pepperoni
A patient with severe kidney disease is started on lithium by a new resident. As the nurse on
duty your best initial response would be to: - correct answers-Contact the resident to remind
him that the client has kidney disease and lithium is contraindicated
Which of the following is generally true of medications used to treat anxiety disorders? - correct
answers-Just as with depression, the most common medications prescribed are serotonin
reuptake inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs).