FOCUS ON NURSING PHARMACOLOGY –
CHAPTER 15: IMMUNE RESPONSE &
IMMUNOSUPPRESSION
Actual Questions and Answers
Expert-Verified Explanation
This Exam contains:
✪ 50 Questions and Answers
✪ Multiple-choice and True/False Format
✪ Expert-Verified Explanations
✪ Verified with Trusted Textbooks
1. Why are burn victims at high risk for infection?
A. They have low body temperatures
B. They lack pain sensation
C. They lose blood volume
D. Their skin integrity is disrupted
Answer: D
EXPLANATION: The skin is the first line of defense; when it’s destroyed, pathogens have
direct access to internal tissues.
2. A client with gunshot wounds and edema is most likely experiencing:
A. Infection
B. Electrolyte imbalance
C. Dehydration
D. Inflammatory process
Answer: D
EXPLANATION: Tissue injury triggers inflammation, which increases capillary permeability,
causing edema.
3. Which white blood cells are primarily responsible for phagocytosis during
infection?
A. Basophils
B. Eosinophils
C. Neutrophils
, D. Lymphocytes
Answer: C
EXPLANATION: Neutrophils are the most abundant leukocytes and are first responders in
bacterial infections, performing phagocytosis.
4. What initiates the inflammatory response following tissue injury?
A. Cytokines
B. Histamines
C. Hageman factor
D. Prostaglandins
Answer: C
EXPLANATION: Hageman factor (Factor XII) activates the kinin system, clotting cascade, and
fibrinolytic pathway—initiating inflammation.
5. The role of thromboxanes in inflammation is best indicated by:
A. Worsening of edema
B. Persistent bleeding
C. Stopped bleeding at injury site
D. Absence of redness
Answer: C
EXPLANATION: Thromboxanes promote platelet aggregation and vasoconstriction, helping to
stop bleeding.
6. Which immunoglobulin is most involved in allergic responses?
A. IgA
B. IgG
C. IgE
D. IgM
Answer: C
EXPLANATION: IgE binds to mast cells and triggers histamine release, producing allergy
symptoms.
7. What describes the role of the major histocompatibility complex (MHC)?
CHAPTER 15: IMMUNE RESPONSE &
IMMUNOSUPPRESSION
Actual Questions and Answers
Expert-Verified Explanation
This Exam contains:
✪ 50 Questions and Answers
✪ Multiple-choice and True/False Format
✪ Expert-Verified Explanations
✪ Verified with Trusted Textbooks
1. Why are burn victims at high risk for infection?
A. They have low body temperatures
B. They lack pain sensation
C. They lose blood volume
D. Their skin integrity is disrupted
Answer: D
EXPLANATION: The skin is the first line of defense; when it’s destroyed, pathogens have
direct access to internal tissues.
2. A client with gunshot wounds and edema is most likely experiencing:
A. Infection
B. Electrolyte imbalance
C. Dehydration
D. Inflammatory process
Answer: D
EXPLANATION: Tissue injury triggers inflammation, which increases capillary permeability,
causing edema.
3. Which white blood cells are primarily responsible for phagocytosis during
infection?
A. Basophils
B. Eosinophils
C. Neutrophils
, D. Lymphocytes
Answer: C
EXPLANATION: Neutrophils are the most abundant leukocytes and are first responders in
bacterial infections, performing phagocytosis.
4. What initiates the inflammatory response following tissue injury?
A. Cytokines
B. Histamines
C. Hageman factor
D. Prostaglandins
Answer: C
EXPLANATION: Hageman factor (Factor XII) activates the kinin system, clotting cascade, and
fibrinolytic pathway—initiating inflammation.
5. The role of thromboxanes in inflammation is best indicated by:
A. Worsening of edema
B. Persistent bleeding
C. Stopped bleeding at injury site
D. Absence of redness
Answer: C
EXPLANATION: Thromboxanes promote platelet aggregation and vasoconstriction, helping to
stop bleeding.
6. Which immunoglobulin is most involved in allergic responses?
A. IgA
B. IgG
C. IgE
D. IgM
Answer: C
EXPLANATION: IgE binds to mast cells and triggers histamine release, producing allergy
symptoms.
7. What describes the role of the major histocompatibility complex (MHC)?
