PSYCHOPHARMACOLOGY NUR660
Actual Questions and Answers
Expert-Verified Explanation
This Exam contains:
✪ 50 Questions and Answers
✪ Multiple-choice and True/False Format
✪ Expert-Verified Explanations
✪ Verified with Trusted Textbooks
1. What is tolerance in psychopharmacology?
A. Drug effect increases with smaller doses
B. The body resists the effect of a new drug
C. Diminishing effect with regular use requiring higher doses
D. Sudden allergic reaction to drug
Answer: C
EXPLANATION: Tolerance refers to reduced response after repeated drug use, necessitating
increased doses for the same effect.
2. What is physiological antagonism?
A. Drugs enhance each other's effect
B. Drugs are not absorbed
C. Two drugs reduce each other's effects
D. One drug replaces another
Answer: C
EXPLANATION: This occurs when two drugs counteract one another’s biological effects,
reducing overall effectiveness.
3. What is potentiation in drug interactions?
A. Two drugs cancel each other
B. One drug increases the effect of another
C. Drug is not absorbed
D. Drug prevents receptor binding
Answer: B
EXPLANATION: Potentiation means one agent intensifies the effect of another without having
that effect on its own.
, 4. What is biotransformation?
A. Distribution of the drug in tissues
B. Excretion of drug
C. Conversion of drug into active or inactive metabolites
D. Passive absorption
Answer: C
EXPLANATION: Biotransformation is typically done by liver enzymes and can activate or
deactivate a drug.
5. What is the first-pass effect?
A. Intravenous drugs bypassing the liver
B. Liver inactivates a portion of orally administered drugs before systemic circulation
C. Kidney clearance of drugs
D. Drug absorption via skin
Answer: B
EXPLANATION: Oral drugs pass through the liver first, reducing the amount reaching
systemic circulation.
6. What is an antagonist?
A. A drug that stimulates receptors
B. A drug that binds but produces no effect
C. A drug that blocks receptor activation
D. A non-drug molecule
Answer: C
EXPLANATION: Antagonists block receptor activity by preventing agonists from binding.
7. What is an agonist?
A. Blocks receptors
B. Destroys enzymes
C. Stimulates a physiological response
D. Converts drugs to metabolites
Answer: C
EXPLANATION: Agonists bind to receptors and mimic natural neurotransmitters to stimulate
effects.
Actual Questions and Answers
Expert-Verified Explanation
This Exam contains:
✪ 50 Questions and Answers
✪ Multiple-choice and True/False Format
✪ Expert-Verified Explanations
✪ Verified with Trusted Textbooks
1. What is tolerance in psychopharmacology?
A. Drug effect increases with smaller doses
B. The body resists the effect of a new drug
C. Diminishing effect with regular use requiring higher doses
D. Sudden allergic reaction to drug
Answer: C
EXPLANATION: Tolerance refers to reduced response after repeated drug use, necessitating
increased doses for the same effect.
2. What is physiological antagonism?
A. Drugs enhance each other's effect
B. Drugs are not absorbed
C. Two drugs reduce each other's effects
D. One drug replaces another
Answer: C
EXPLANATION: This occurs when two drugs counteract one another’s biological effects,
reducing overall effectiveness.
3. What is potentiation in drug interactions?
A. Two drugs cancel each other
B. One drug increases the effect of another
C. Drug is not absorbed
D. Drug prevents receptor binding
Answer: B
EXPLANATION: Potentiation means one agent intensifies the effect of another without having
that effect on its own.
, 4. What is biotransformation?
A. Distribution of the drug in tissues
B. Excretion of drug
C. Conversion of drug into active or inactive metabolites
D. Passive absorption
Answer: C
EXPLANATION: Biotransformation is typically done by liver enzymes and can activate or
deactivate a drug.
5. What is the first-pass effect?
A. Intravenous drugs bypassing the liver
B. Liver inactivates a portion of orally administered drugs before systemic circulation
C. Kidney clearance of drugs
D. Drug absorption via skin
Answer: B
EXPLANATION: Oral drugs pass through the liver first, reducing the amount reaching
systemic circulation.
6. What is an antagonist?
A. A drug that stimulates receptors
B. A drug that binds but produces no effect
C. A drug that blocks receptor activation
D. A non-drug molecule
Answer: C
EXPLANATION: Antagonists block receptor activity by preventing agonists from binding.
7. What is an agonist?
A. Blocks receptors
B. Destroys enzymes
C. Stimulates a physiological response
D. Converts drugs to metabolites
Answer: C
EXPLANATION: Agonists bind to receptors and mimic natural neurotransmitters to stimulate
effects.
