nanomedicine test 3 Questions with Detailed
Verified Answers (100% Correct Answers) Already
Graded A+
Quiz: difference between nano devices and nanoparticles, Ans: - nano devices:
they are made of nanoparticles (usually with different composition -- ex.
microneedles and nano needles, and nano-valves for drug delivery)
- nanoparticles: particle of any shape with dimensions in the 1 x 10 ^-9 - 1x10
^-7 (1-100nm)
Quiz: why did we study micro-needles if they are not a nano object?, Ans:
because they are still relevant in the field of medicine. Microneedles permit
transport of macromolecules, as well as possibly supramolecular complexes
and Microparticles
Quiz: which skin layer can be reached using micro-needles?, Ans: stratum
corneum
Quiz: describe the three transdermal drug delivery methods using micro-
needles, Ans: 1. poke with a patch -- use for insulin delivery into diabetic
hairless rats (sol of insulin was placed on top of the micro needle array and
left)
2. coat and poke -- used for protein vaccine delivery (microneedles prepared
with dry film coating of antigen and then inserted into skin of hairless guinea
pig -- possible allergy treatment?)
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, 3. dip and scrape -- used for DNA delivery (arrays dipped into a solution of DNA
and scraped multiple times across the skin of mice to create micro abrasions)
Quiz: which skin layer can be reached using nano-needles?, Ans: can only
reach the upper layer of the epidermis because they are too small to penetrate
the stratum corneum
Quiz: what are the main applications of nano-needles, Ans: drug delivery
without nanoparticles and manipulation of organelles
Quiz: describe and understand how it works the nano-valve designed by Zink
et al, Ans: - a nano-valve that can be opened and closed (trap and release
molecules0 -- could be used for drug delivery such as insulin release
how it works:
1. guest molecule is loaded into the pores (by diffusion)
2. valve is closed bc of oxidation of TTF
3. valve is opened by adding ascorbic acid to reduce TTF (position of CBPQT4
ring changes)
4. release of the guest molecule
© 2025 Get it right Stuvia US All rights reserved
Verified Answers (100% Correct Answers) Already
Graded A+
Quiz: difference between nano devices and nanoparticles, Ans: - nano devices:
they are made of nanoparticles (usually with different composition -- ex.
microneedles and nano needles, and nano-valves for drug delivery)
- nanoparticles: particle of any shape with dimensions in the 1 x 10 ^-9 - 1x10
^-7 (1-100nm)
Quiz: why did we study micro-needles if they are not a nano object?, Ans:
because they are still relevant in the field of medicine. Microneedles permit
transport of macromolecules, as well as possibly supramolecular complexes
and Microparticles
Quiz: which skin layer can be reached using micro-needles?, Ans: stratum
corneum
Quiz: describe the three transdermal drug delivery methods using micro-
needles, Ans: 1. poke with a patch -- use for insulin delivery into diabetic
hairless rats (sol of insulin was placed on top of the micro needle array and
left)
2. coat and poke -- used for protein vaccine delivery (microneedles prepared
with dry film coating of antigen and then inserted into skin of hairless guinea
pig -- possible allergy treatment?)
© 2025 Get it right Stuvia US All rights reserved
, 3. dip and scrape -- used for DNA delivery (arrays dipped into a solution of DNA
and scraped multiple times across the skin of mice to create micro abrasions)
Quiz: which skin layer can be reached using nano-needles?, Ans: can only
reach the upper layer of the epidermis because they are too small to penetrate
the stratum corneum
Quiz: what are the main applications of nano-needles, Ans: drug delivery
without nanoparticles and manipulation of organelles
Quiz: describe and understand how it works the nano-valve designed by Zink
et al, Ans: - a nano-valve that can be opened and closed (trap and release
molecules0 -- could be used for drug delivery such as insulin release
how it works:
1. guest molecule is loaded into the pores (by diffusion)
2. valve is closed bc of oxidation of TTF
3. valve is opened by adding ascorbic acid to reduce TTF (position of CBPQT4
ring changes)
4. release of the guest molecule
© 2025 Get it right Stuvia US All rights reserved
