STUDENT C O M P A N I O N
F U N D A M
z
E N T A L S O F
Biochemistry
LIFE AT z
THE
z MOLECULAR
LEVEL
z
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
z z z z
Donald Voet Judith G. Voet Charlotte W. Pratt
z z z z z z
,This zpage zis zintentionally zleft zblank
,STUDENT COMPANION TO ACCOMPANY z z z
FUNDAMENTALS OF z
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
z z z z
Fourth Edition z
Akif Uzman
z
University of Houston z z
Jerry Johnson
z
University of Houston z z
Joseph Eichberg z
University of Houston z z
William Widger z
University of Houston z z
Donald Voet z
University of Pennsylvania z z
Judith G. Voet z z
Swarthmore College z
Charlotte W. Pratt z z
Seattle, Washington z
JOHN zWILEY z& zSONS, zINC
, Cover zDesigner zMadelyn zLesure
zCover zIllustration zNorm
zChristiansenzCover zPhotos
(Vitruvian zMan): z© zOdysseus/Alamy zand z© zDennis zHallinan/Alamy
Molecular zstructures zclockwise zfrom ztop: zbased zon zX-ray zstructures zthat zwere zrespectively
zdetermined zby zRichard zDickerson zand zHorace zDrew, zCaltech; zGerard zBunick, zUniversity zof
zTennessee; zThomas zSteitz, zYale zUniversity; zAlfonso zMondragón, zNorthwestern zUniversity; zVenki
zRamakrishnan, zMRC zLaboratory zof zMolecular zBiology, zCambridge, zU.K.; zAndrew zLeslie zand zJohn
zWalker, zMRC zLaboratoryzof zMolecular zBiology, zCambridge, zU.K.
Founded zin z1807, zJohn zWiley z& zSons, zInc. zhas zbeen za zvalued zsource zof zknowledge zand
zunderstanding zfor zmore zthan z200 zyears, zhelping zpeople zaround zthe zworld zmeet ztheir zneeds zand zfulfill
ztheir zaspirations. zOur zcompany zis zbuilt zon za zfoundation zof zprinciples zthat zinclude zresponsibility zto zthe
zcommunities zwe zserve zandzwhere zwe zlive zand zwork. zIn z2008, zwe zlaunched za zCorporate zCitizenship
zInitiative, za zglobal zeffort zto zaddress zthe zenvironmental, zsocial, zeconomic, zand zethical zchallenges zwe
zface zin zour zbusiness. zAmong zthe zissues zwe zare zaddressing zare zcarbon zimpact, zpaper zspecifications
zand zprocurement, zethical zconduct zwithin zour zbusiness zand zamong zour zvendors, zand zcommunity zand
zcharitable zsupport. zFor zmore zinformation, zplease zvisit zour zwebsite: zwww.wiley.com/go/citizenship.
Copyright z© z2012 John zWiley z& zSons, zInc.
All zrights zreserved. zNo zpart zof zthis zpublication zmay zbe zreproduced, zstored zin za zretrieval zsystem zor
ztransmitted zin zany zform zor zby zany zmeans, zelectronic, zmechanical, zphotocopying, zrecording, zscanning
zor zotherwise, zexcept zas zpermitted zunder zSections z107 zor z108 zof zthe z1976 zUnited zStates zCopyright
zAct, zwithout zeither zthe zprior zwritten zpermission zof zthe zPublisher, zor zauthorization zthrough zpayment
zof zthe zappropriate zper-copy zfee zto zthe zCopyright zClearance zCenter, zInc., z222 zRosewood zDrive,
zDanvers, zMA z01923, zwebsite zwww.copyright.com. zRequests zto zthe zPublisher zfor zpermission zshould
zbe zaddressed zto zthezPermissions zDepartment, zJohn zWiley z& zSons, zInc. z111 zRiver zStreet, zHoboken,
zNJ z07030-5774, z(201) z748-6011, zfax z(201) z748-6008, zwebsite zhttp://www.wiley.com/go/permissions.
To zorder zbooks zor zfor zcustomer zservice, zplease zcall z1-800-CALL zWILEY z(225-5945).
Student zCompanion z(paperback) ISBN-13 z 978-1-1182-1827-3
Printed zin zthe zUnited zStates zof
Americaz10 z 9 z8 z7 z 6 z5 z4 z 3 z2 z1
z
F U N D A M
z
E N T A L S O F
Biochemistry
LIFE AT z
THE
z MOLECULAR
LEVEL
z
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
z z z z
Donald Voet Judith G. Voet Charlotte W. Pratt
z z z z z z
,This zpage zis zintentionally zleft zblank
,STUDENT COMPANION TO ACCOMPANY z z z
FUNDAMENTALS OF z
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
z z z z
Fourth Edition z
Akif Uzman
z
University of Houston z z
Jerry Johnson
z
University of Houston z z
Joseph Eichberg z
University of Houston z z
William Widger z
University of Houston z z
Donald Voet z
University of Pennsylvania z z
Judith G. Voet z z
Swarthmore College z
Charlotte W. Pratt z z
Seattle, Washington z
JOHN zWILEY z& zSONS, zINC
, Cover zDesigner zMadelyn zLesure
zCover zIllustration zNorm
zChristiansenzCover zPhotos
(Vitruvian zMan): z© zOdysseus/Alamy zand z© zDennis zHallinan/Alamy
Molecular zstructures zclockwise zfrom ztop: zbased zon zX-ray zstructures zthat zwere zrespectively
zdetermined zby zRichard zDickerson zand zHorace zDrew, zCaltech; zGerard zBunick, zUniversity zof
zTennessee; zThomas zSteitz, zYale zUniversity; zAlfonso zMondragón, zNorthwestern zUniversity; zVenki
zRamakrishnan, zMRC zLaboratory zof zMolecular zBiology, zCambridge, zU.K.; zAndrew zLeslie zand zJohn
zWalker, zMRC zLaboratoryzof zMolecular zBiology, zCambridge, zU.K.
Founded zin z1807, zJohn zWiley z& zSons, zInc. zhas zbeen za zvalued zsource zof zknowledge zand
zunderstanding zfor zmore zthan z200 zyears, zhelping zpeople zaround zthe zworld zmeet ztheir zneeds zand zfulfill
ztheir zaspirations. zOur zcompany zis zbuilt zon za zfoundation zof zprinciples zthat zinclude zresponsibility zto zthe
zcommunities zwe zserve zandzwhere zwe zlive zand zwork. zIn z2008, zwe zlaunched za zCorporate zCitizenship
zInitiative, za zglobal zeffort zto zaddress zthe zenvironmental, zsocial, zeconomic, zand zethical zchallenges zwe
zface zin zour zbusiness. zAmong zthe zissues zwe zare zaddressing zare zcarbon zimpact, zpaper zspecifications
zand zprocurement, zethical zconduct zwithin zour zbusiness zand zamong zour zvendors, zand zcommunity zand
zcharitable zsupport. zFor zmore zinformation, zplease zvisit zour zwebsite: zwww.wiley.com/go/citizenship.
Copyright z© z2012 John zWiley z& zSons, zInc.
All zrights zreserved. zNo zpart zof zthis zpublication zmay zbe zreproduced, zstored zin za zretrieval zsystem zor
ztransmitted zin zany zform zor zby zany zmeans, zelectronic, zmechanical, zphotocopying, zrecording, zscanning
zor zotherwise, zexcept zas zpermitted zunder zSections z107 zor z108 zof zthe z1976 zUnited zStates zCopyright
zAct, zwithout zeither zthe zprior zwritten zpermission zof zthe zPublisher, zor zauthorization zthrough zpayment
zof zthe zappropriate zper-copy zfee zto zthe zCopyright zClearance zCenter, zInc., z222 zRosewood zDrive,
zDanvers, zMA z01923, zwebsite zwww.copyright.com. zRequests zto zthe zPublisher zfor zpermission zshould
zbe zaddressed zto zthezPermissions zDepartment, zJohn zWiley z& zSons, zInc. z111 zRiver zStreet, zHoboken,
zNJ z07030-5774, z(201) z748-6011, zfax z(201) z748-6008, zwebsite zhttp://www.wiley.com/go/permissions.
To zorder zbooks zor zfor zcustomer zservice, zplease zcall z1-800-CALL zWILEY z(225-5945).
Student zCompanion z(paperback) ISBN-13 z 978-1-1182-1827-3
Printed zin zthe zUnited zStates zof
Americaz10 z 9 z8 z7 z 6 z5 z4 z 3 z2 z1
z
