RATED A+ | 2024/2025 GUIDE
1. Glucose Production & Release ANS >> -All cells in the body need energy to
function
• primarily comes from glucose; a type of sugar found in carbohydrates.
-between meals, glucose stores in the liver are released into the bloodstream
• ensures a constant source of energy for the body
-After a meal, carbohydrates are digested & release glucose into the bloodstream
2. Insulin Release in Type I Diabetes ANS >> -As glucose levels in the blood
rise, beta cells in the pancreas are stimulated to release insulin
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,-Insulin halts the livers glucose release & initiates small amounts of glucose to be
stored in the liver for future use
-type 1 diabetes, pancreatic beta cells are damaged or destroyed
• damaged beta cells produce little to no insulin
3. Systemic Insulin and Glucose in Type I Diabetes ANS >> -Insulin &
glucose travel through the bloodstream to reach cells throughout the body
-Due to diminished insulin production, patients with type 1 diabetes have a low
insulin concentration & high glucose (sugar) concentration in their blood
4. Glucose Absorption in Type I Diabetes ANS >> -Insulin is required for glucose
to enter cells & be used as energy
-Once arriving at the intended cell, insulin binds to specialized receptors on the cell
surface
• initiates glucose transporters to open & glucose to flow into the cell
-type 1 diabetes, low levels of insulin prevent adequate amounts of glucose from
entering the cell
• Because glucose remains in the bloodstream & is not used by the cell as energy,
patients with type 1 diabetes may experience fatigue, exhaustion, & dizziness
5. Insulin Release in Type II Diabetes ANS >> -As glucose levels in the blood
rise, beta cells in the pancreas are stimulated to release insulin
-insulin halts the livers glucose release & initiates small amounts of glucose to be
stored in the liver for future use
-In type 2 diabetes, pancreatic beta cells become damaged or destroyed over time
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,• damaged beta cells produce little to no insulin.
6. Systemic Insulin and Glucose in Type II Diabetes ANS >> -Insulin &
glucose travel through the bloodstream to reach cells throughout the body
-Insulin is required for glucose to enter cells & be used as energy
-In type 2 diabetes, insulin is not used properly & glucose remains in the bloodstream
• leads to high levels of glucose in the blood (hyperglycemia).
7. Glucose Absorption in Type II Diabetes ANS >> -Once arriving at the
intended cell, insulin binds to specialized receptors on the cell surface
• initiates glucose transporters to open & glucose to flow into the cell
-type 2 diabetes, the body is resistant to the effects of insulin & does not properly
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, bind to insulin receptors
N N N
-Due to insulin resistance & resulting hyperglycemia, patients with type 2
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Ndiabetes may experience increased thirst or hunger, fatigue, blurry vision, and
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Nslow-healing wounds N
8. Hypothyroidism ANS >> -an underproduction of the hormone thyroxine (T4)
N N NN N N N N N N
-When the thyroid produces too little thyroxine
N N N N N N
• body's metabolism slows down
N N N
• wide array of effects on the body
N N N N N N
-Hypothyroidism can cause ANS >> N N N N N
• fatigue
• depressed mood N
• slow heart rate
N N
• constipation
• weight gain N
• irregular menstrual periods N N
-more common in women >60 & people who have a family hx of the condition
N N N N N N N N N N N N N N
9. Hyperthyroidism ANS >> -an overproduction of thyroid hormones ANS >> N N NN N N N N N N N
triiodothyronine (T3), & thyroxine (T4)
N N N N N
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