BIOCHEM WGU PA Test Comprehensive
Questions (Frequently Tested) with
Verified Answers Graded A+
Which mRNA sequence results in a polypeptide that contains three amino acids? - Answer: 5' -
CUU GAU ACU UAG - 3'
Which template strand DNA sequence would result in the amino acid (Ser)? - Answer: 5' - CGA -
3'
Pay attention. The TEMPLATE STRAND DNA is a 3'-5' so it's flipped.
What is the complementary sequence for the following DNA sequence?
5' - GCC ATC TCG AAT - 3' - Answer: 5' - ATT CGA GAT GGC - 3'
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of
four complete PCR cycles? - Answer: 16
What is the function of DNA polymerase in the process of PCR? - Answer: It recognizes the
primers and uses the available dNTPs to replicate the template DNA sequence.
What is the amino acid in position 118 that results from a single nucleotide insertion
immediately following the three guanines that encode for glycine 116? - Answer: Thr
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
, What change in codons corresponds to this mutation? - Answer: GAA to GTA
What are possible blood types of the parents of a patient with blood type AB? - Answer: A and B
Given the pedigree chart, what type of muscular dystrophy is most likely affecting this family? -
Answer: Becker's: X-linked recessive
Which pair of chromosomes accurately depicts the genotype of a person with an autosomal
recessive mutant HBB allele and sickle cell anemia? - Answer: C
Studies have shown that increased expression of two genes called SIRT1 and SIRT2 is associated
with chronic exposure to cocaine and contributes to drug addiction.
What difference in the regions of the SIRT1 and SIRT2 genes in people addicted to cocaine
increases their expression? - Answer: The nucleosomes become more widely spaced.
What occurs during the process of alternative splicing of mRNA? - Answer: Alternate
combinations of exons within the same gene are linked together.
Which type of mammalian DNA damage repair requires the presence of the chromosome that is
homologous to the damaged chromosome? - Answer: Recombination
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs when one or more of
the genes that perform nucleotide excision repair are nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the general population? -
Answer: The mutation rate of all other genes is higher due to failure to repair.
Which portion of the amino acid is inside the box? - Answer: Amino group
Questions (Frequently Tested) with
Verified Answers Graded A+
Which mRNA sequence results in a polypeptide that contains three amino acids? - Answer: 5' -
CUU GAU ACU UAG - 3'
Which template strand DNA sequence would result in the amino acid (Ser)? - Answer: 5' - CGA -
3'
Pay attention. The TEMPLATE STRAND DNA is a 3'-5' so it's flipped.
What is the complementary sequence for the following DNA sequence?
5' - GCC ATC TCG AAT - 3' - Answer: 5' - ATT CGA GAT GGC - 3'
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of
four complete PCR cycles? - Answer: 16
What is the function of DNA polymerase in the process of PCR? - Answer: It recognizes the
primers and uses the available dNTPs to replicate the template DNA sequence.
What is the amino acid in position 118 that results from a single nucleotide insertion
immediately following the three guanines that encode for glycine 116? - Answer: Thr
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
, What change in codons corresponds to this mutation? - Answer: GAA to GTA
What are possible blood types of the parents of a patient with blood type AB? - Answer: A and B
Given the pedigree chart, what type of muscular dystrophy is most likely affecting this family? -
Answer: Becker's: X-linked recessive
Which pair of chromosomes accurately depicts the genotype of a person with an autosomal
recessive mutant HBB allele and sickle cell anemia? - Answer: C
Studies have shown that increased expression of two genes called SIRT1 and SIRT2 is associated
with chronic exposure to cocaine and contributes to drug addiction.
What difference in the regions of the SIRT1 and SIRT2 genes in people addicted to cocaine
increases their expression? - Answer: The nucleosomes become more widely spaced.
What occurs during the process of alternative splicing of mRNA? - Answer: Alternate
combinations of exons within the same gene are linked together.
Which type of mammalian DNA damage repair requires the presence of the chromosome that is
homologous to the damaged chromosome? - Answer: Recombination
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs when one or more of
the genes that perform nucleotide excision repair are nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the general population? -
Answer: The mutation rate of all other genes is higher due to failure to repair.
Which portion of the amino acid is inside the box? - Answer: Amino group
