Test bank for Tietz Fundamentals of Clinical
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Chemistry and Molecular Diagnostics,8th Edition by
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Nader Rifai, PhD Chapters 1 - 49
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if in need of any academic assistance email at
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, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresisoo oo
Chapter 12. Chromatography oo oo
Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation oo oo
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes oo oo oo
Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates oo oo
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones oo oo
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals oo o o oo
IV. Pathophysiology
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Chapter 33. Diabetes oo oo
if in need of any academic assistance email at
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, Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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if in need of any academic assistance email at
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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TestBank
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MULTIPLE CHOICE oo
1. An individual working in a clinical chemistry laboratory is married to a sales
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representative who works for a company that sells chemistry laboratory supplies. When
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the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
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this individual onlyrecommends the spouse’s company as the vendor. This is considered to
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be a(n):
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a. accounting issue. oo
b. possible conflict of interest. oo oo oo
c. maintenance of confidentiality issue. oo oo oo
d. problem with resource allocation. oo oo oo
ANS: B oo
Concern has been raised over the interrelationships between practitioners in the medical
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fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
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profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and
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manufacturers and providers of diagnostic equipment and supplies. These concerns led the
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National Institutes of Health (NIH) in 1995 to require official institutional review of
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financial disclosure by researchers and management of situations in which disclosure
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indicates potentialconflicts of interest.
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DIF: 1 REF: oo oo oo Page 4-5 oo OBJ: 6 | 7 oo oo oo
2. A patient visits her physician stating that her prescribed painkiller is not working to
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reduce the pain following her recent surgery. A friend of the patient claims that the same
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painkiller―worked wonders‖ to reduce her pain after the same surgery. The physician
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states that the difference in the effect of the drug might be caused by , which is studied
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in pharmacogenetics.
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a. epidemiology
b. an inherited disease oo oo
c. a conflict of interestoo oo oo
d. a genetic variation in drug-metabolizing enzymes
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ANS: D oo
Pharmacogenetics is the study of the genetic variation of drug metabolism oo oo oo oo oo oo oo oo oo oo
betweenindividuals.
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DIF: 1 REF: oo oo o o Page 3 oo OBJ: 1 oo
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
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the name of a close friend printed on the bar-coded label. The genetic test that is ordered
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on thefriend’s sample would provide diagnostic information about a disorder that has a
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poor prognosis, and the test is usually performed by John. He asks a fellow employee to
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analyzethe sample for him and not divulge the results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. oo oo oo oo oo oo
b. a conflict of interest.
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c. resource allocation. oo
d. diagnostic accuracy. oo
if in need of any academic assistance email at
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Chemistry and Molecular Diagnostics,8th Edition by
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Nader Rifai, PhD Chapters 1 - 49
oo oo oo oo oo oo oo oo
if in need of any academic assistance email at
oo oo oo oo oo oo oo oo oo oo
, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
oo oo oo oo oo oo oo oo
oo
oo oo
Table of contents:
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I. Principles Of Laboratory Medicine
oo oo oo oo
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
oo oo oo oo oo oo oo oo
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
oo oo oo oo oo oo oo oo oo oo oo
Chapter 3. Clinical Evaluation of Methods
oo oo oo oo oo
Chapter 4. Evidence-Based Laboratory Medicine
oo oo oo oo
Chapter 5. Establishment and Use of Reference Values
oo oo oo oo oo oo oo
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
oo oo oo oo oo oo oo oo
Chapter 7. Quality Management
oo oo oo
II. Analytical Techniques And Instrumentation
oo oo oo oo
Chapter 8. Principles of Basic Techniques and Laboratory Safety
oo oo oo oo oo oo oo oo
Chapter 9. Optical Techniques
oo oo oo
Chapter 10. Electrochemistry and Chemical Sensors
oo oo oo oo oo
Chapter 11. Electrophoresisoo oo
Chapter 12. Chromatography oo oo
Chapter 13. Mass Spectrometry
oo oo oo
Chapter 14. Enzyme and Rate Analyses
oo oo oo oo oo
Chapter 15. Immunochemical Techniques
oo oo oo
Chapter 16 Automation oo oo
Chapter 17. Point-of-Care Instrumentation
oo oo oo
III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
oo oo oo oo oo oo
Chapter 19. Serum Enzymes oo oo oo
Chapter 20. Tumor Markers and Cancer Genes
oo oo oo oo oo oo
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
oo oo oo oo oo oo oo oo oo oo oo
Chapter 22. Carbohydrates oo oo
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
oo oo oo oo oo oo oo oo oo
Chapter 24. Electrolytes and Blood Gases
oo oo oo oo oo
Chapter 25. Hormones oo oo
Chapter 26. Catecholamines and Serotonin
oo o o oo oo
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
oo o o oo oo oo oo
Chapter 28. Hemoglobin, Iron, and Bilirubin
oo oo oo oo oo
Chapter 29. Porphyrins and Porphyrias
oo oo oo oo
Chapter 30. Therapeutic Drugs and Their Management
oo oo oo oo oo oo
Chapter 31. Clinical Toxicology
oo oo oo
Chapter 32. Toxic Metals oo o o oo
IV. Pathophysiology
o o
Chapter 33. Diabetes oo oo
if in need of any academic assistance email at
oo oo oo oo oo oo oo oo oo oo
, Chapter 34. Cardiovascular Disease
oo o o oo
Chapter 35. Kidney Disease
oo oo oo
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
oo o o oo oo oo oo oo oo oo oo
Chapter 37. Liver Disease
oo oo oo oo
Chapter 38. Gastrointestinal and Pancreatic Diseases
oo o o oo oo oo
Chapter 39. Disorders of Bone and Mineral Metabolism
oo oo oo oo oo oo oo oo
Chapter 40. Disorders of the Pituitary Gland
oo oo oo oo oo oo oo
Chapter 41. Disorders of the Adrenal Cortex
oo o o oo oo oo oo
Chapter 42. Thyroid Disorders
oo o o oo
Chapter 43. Reproduction-Related Disorders
oo o o oo
Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
oo o o oo oo oo oo oo oo
Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
o o oo
Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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if in need of any academic assistance email at
oo oo oo oo oo oo oo oo oo oo
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
oo oo oo oo oo oo oo oo
TestBank
oo o
MULTIPLE CHOICE oo
1. An individual working in a clinical chemistry laboratory is married to a sales
oo oo oo oo oo oo oo oo oo oo oo oo
representative who works for a company that sells chemistry laboratory supplies. When
oo oo oo oo oo oo oo oo oo oo oo oo
the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
oo oo oo oo oo oo oo oo oo oo oo oo oo oo
this individual onlyrecommends the spouse’s company as the vendor. This is considered to
oo oo oo o oo oo oo oo oo oo oo oo oo oo
be a(n):
oo oo
a. accounting issue. oo
b. possible conflict of interest. oo oo oo
c. maintenance of confidentiality issue. oo oo oo
d. problem with resource allocation. oo oo oo
ANS: B oo
Concern has been raised over the interrelationships between practitioners in the medical
oo oo oo oo oo oo oo oo oo oo oo
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
oo o oo oo oo oo oo oo oo oo oo oo
profession.
oo
Similarly, relationships have been scrutinized between clinical laboratorians and
oo oo oo oo oo oo oo oo
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
oo oo oo oo oo oo oo oo oo oo oo oo
National Institutes of Health (NIH) in 1995 to require official institutional review of
oo oo oo oo oo oo oo oo oo oo oo oo oo
financial disclosure by researchers and management of situations in which disclosure
oo oo oo oo oo oo oo oo oo oo oo
indicates potentialconflicts of interest.
oo oo o oo oo
DIF: 1 REF: oo oo oo Page 4-5 oo OBJ: 6 | 7 oo oo oo
2. A patient visits her physician stating that her prescribed painkiller is not working to
oo oo oo oo oo oo oo oo oo oo oo oo oo
reduce the pain following her recent surgery. A friend of the patient claims that the same
oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo
painkiller―worked wonders‖ to reduce her pain after the same surgery. The physician
oo o oo oo oo oo oo oo oo oo oo oo oo
states that the difference in the effect of the drug might be caused by , which is studied
oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo
in pharmacogenetics.
oo oo
a. epidemiology
b. an inherited disease oo oo
c. a conflict of interestoo oo oo
d. a genetic variation in drug-metabolizing enzymes
oo oo oo oo oo
ANS: D oo
Pharmacogenetics is the study of the genetic variation of drug metabolism oo oo oo oo oo oo oo oo oo oo
betweenindividuals.
oo o
DIF: 1 REF: oo oo o o Page 3 oo OBJ: 1 oo
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
oo oo oo oo oo oo oo oo oo oo oo oo oo
the name of a close friend printed on the bar-coded label. The genetic test that is ordered
oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo
on thefriend’s sample would provide diagnostic information about a disorder that has a
oo oo o oo oo oo oo oo oo oo oo oo oo oo
poor prognosis, and the test is usually performed by John. He asks a fellow employee to
oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo oo
analyzethe sample for him and not divulge the results. This ethical issue concerns:
oo o oo oo oo oo oo oo oo oo oo oo oo oo
a. confidentiality of patient genetic and medical information. oo oo oo oo oo oo
b. a conflict of interest.
oo oo oo
c. resource allocation. oo
d. diagnostic accuracy. oo
if in need of any academic assistance email at
oo oo oo oo oo oo oo oo oo oo
