1
ONS Chemotherapy Immunotherapy
Certificate Questions and Correct
Answers
Question: Define neoadjuvant therapy
Answer: Treatment is given prior to surgery to shrink the tumor
Question: Define adjuvant therapy
Answer: Additional cancer treatment given after the primary treatment to
lower the risk that the cancer reoccur
Question: 3 subcategories of alkylating agents:
Answer: 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
Question: Common alkylating agents:
Answer: Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Question: Common platinum-based agents:
Answer: Cisplatin (Platinol)
Carboplatin (Paraplatin)
Question: What is unique about nitrosoureas agents?
Answer: Able to cross the blood-brain barrier; can be effective in treating
some brain tumors
Pretest - Stuvia US
,2
Question: Common nitrosoureas agents:
Answer: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Question: Hypersensitivity can occur with late doses of:
Answer: Carboplatin
Question: These agents are typically categorized as highly emetogenic:
Answer: 1. Alkylating agents
2. Nitrosoureas
Question: Pre-administration labs for alkylating agents and
nitrosoureas:
Answer: BUN
Creatinine
CBC w/ diff
Question: What is the medication Mesna used for?
Answer: Bladder protectant with administration of cyclophosphamide or
ifosfamide
Question: Instruct pts receiving ________ to avoid exposure to cold air
and consuming cold fluids for 3-4 days following treatment
Answer: Oxaliplatin
Question: How do antimetabolites function?
Answer: By blocking DNA and RNA growth by interfering with enzymes
needed for normal cell metabolism
Question: Antimetabolites work in the ___ phase.
Answer: S
Pretest - Stuvia US
, 3
Question: Common side effects of antimetabolites:
Answer: Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Question: Common antimetabolite drugs:
Answer: Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
Question: The institute for Safe Medication Practices recommends what
route of administration for vincristine?
Answer: IV piggyback via gravity
Question: Anthracycline antitumor abx work by:
Answer: Interfering with enzymes necessary for DNA to replicate in ALL
phases of the cell cycle
Question: The two major classifications of antitumor antibiotics are:
Answer: Anthracyclines
Non-anthracyclines
Question: Common anthracycline antitumor abx:
Answer: Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Pretest - Stuvia US
ONS Chemotherapy Immunotherapy
Certificate Questions and Correct
Answers
Question: Define neoadjuvant therapy
Answer: Treatment is given prior to surgery to shrink the tumor
Question: Define adjuvant therapy
Answer: Additional cancer treatment given after the primary treatment to
lower the risk that the cancer reoccur
Question: 3 subcategories of alkylating agents:
Answer: 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
Question: Common alkylating agents:
Answer: Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Question: Common platinum-based agents:
Answer: Cisplatin (Platinol)
Carboplatin (Paraplatin)
Question: What is unique about nitrosoureas agents?
Answer: Able to cross the blood-brain barrier; can be effective in treating
some brain tumors
Pretest - Stuvia US
,2
Question: Common nitrosoureas agents:
Answer: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Question: Hypersensitivity can occur with late doses of:
Answer: Carboplatin
Question: These agents are typically categorized as highly emetogenic:
Answer: 1. Alkylating agents
2. Nitrosoureas
Question: Pre-administration labs for alkylating agents and
nitrosoureas:
Answer: BUN
Creatinine
CBC w/ diff
Question: What is the medication Mesna used for?
Answer: Bladder protectant with administration of cyclophosphamide or
ifosfamide
Question: Instruct pts receiving ________ to avoid exposure to cold air
and consuming cold fluids for 3-4 days following treatment
Answer: Oxaliplatin
Question: How do antimetabolites function?
Answer: By blocking DNA and RNA growth by interfering with enzymes
needed for normal cell metabolism
Question: Antimetabolites work in the ___ phase.
Answer: S
Pretest - Stuvia US
, 3
Question: Common side effects of antimetabolites:
Answer: Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Question: Common antimetabolite drugs:
Answer: Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
Question: The institute for Safe Medication Practices recommends what
route of administration for vincristine?
Answer: IV piggyback via gravity
Question: Anthracycline antitumor abx work by:
Answer: Interfering with enzymes necessary for DNA to replicate in ALL
phases of the cell cycle
Question: The two major classifications of antitumor antibiotics are:
Answer: Anthracyclines
Non-anthracyclines
Question: Common anthracycline antitumor abx:
Answer: Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Pretest - Stuvia US
