MENOPAUSE PRACTICE QUESTIONS
The most effective treatment to alleviate postmenopausal vasomotor symptoms (hot
flashes and night sweats) is:
A. Estrogen therapy
B. Selective estrogen-receptor modulators (SERMs)
C. Testosterone therapy
D. Clonidine - Answers :A.
Which of the following CYP450 isoenzymes metabolizes both estrogen and
medroxyprogesterone?
A. 3A4
B. 1A2
C. 2D6
D. All of the above - Answers :A.
Continued vasomotor symptoms in a 52-year-old postmenopausal woman with a history
of hysterectomy receiving 0.3 mg of oral conjugated equine estrogens can best be
managed by:
A. Changing to a SERM
B. Changing to gabapentin
C. Increasing the daily estrogen dose
D. Decreasing the daily estrogen dose - Answers :C.
A 54-year-old postmenopausal woman is complaining of vaginal dryness, itching, and
pain with intercourse. She has not had any other problems associated with menopause
and has an intact uterus. Which of the following recommendations is the best treatment
option that balances risks and benefits for the management of this patient's symptoms?
A. Oral conjugated estrogen + medroxyprogesterone acetate
B. Transdermal estradiol + micronized oral progesterone
C. Intravaginal estrogen cream + oral progestogen
D. Intravaginal estrogen cream - Answers :D.
Conjugated equine estrogen therapy alone has demonstrated to significantly increase
the risk of:
A. Coronary heart disease
B. Stroke
C. Colorectal cancer
D. Breast cancer - Answers :B.
The most effective treatment to alleviate postmenopausal vasomotor symptoms (hot
flashes and night sweats) is:
A. Estrogen therapy
B. Selective estrogen-receptor modulators (SERMs)
C. Testosterone therapy
D. Clonidine - Answers :A.
Which of the following CYP450 isoenzymes metabolizes both estrogen and
medroxyprogesterone?
A. 3A4
B. 1A2
C. 2D6
D. All of the above - Answers :A.
Continued vasomotor symptoms in a 52-year-old postmenopausal woman with a history
of hysterectomy receiving 0.3 mg of oral conjugated equine estrogens can best be
managed by:
A. Changing to a SERM
B. Changing to gabapentin
C. Increasing the daily estrogen dose
D. Decreasing the daily estrogen dose - Answers :C.
A 54-year-old postmenopausal woman is complaining of vaginal dryness, itching, and
pain with intercourse. She has not had any other problems associated with menopause
and has an intact uterus. Which of the following recommendations is the best treatment
option that balances risks and benefits for the management of this patient's symptoms?
A. Oral conjugated estrogen + medroxyprogesterone acetate
B. Transdermal estradiol + micronized oral progesterone
C. Intravaginal estrogen cream + oral progestogen
D. Intravaginal estrogen cream - Answers :D.
Conjugated equine estrogen therapy alone has demonstrated to significantly increase
the risk of:
A. Coronary heart disease
B. Stroke
C. Colorectal cancer
D. Breast cancer - Answers :B.
