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Nursing pharmacology

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Nursing pharmacology

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Nursing Pharmacology (Drugs). Revision notes in
question-answer like form.guaranteed A+

albuterol - Correct Answers-(SABA) short acting beta 2 receptor agonist, used for
bronchospasm, acute symptoms of asthma



acetaminophen - Correct Answers-centrally acting cox inhibitor; analgesic and antipyretic
properties; no antiinflammatory,antirheumatic properties



acyclovir - Correct Answers-Antimetabolite for Treating Herpes Simplex Virus & Varicella-Zoster
Virus Infections;

MOAs: Purine necleoside analog: DNA polymerase inhibitor, suppresses synthesis of viral DNA,
resistance.



amiodarone - Correct Answers-Class 3 Potassium channel blocker

Only approved for life-threatening dysrhythmias.

Delays repolarization and extends action potential of heart muscle cells.

SE: Profound hypotension."



amoxicillin - Correct Answers-Broad-spectrum penicillin active against H. influenzae, E. coli, and
N. Gonorrhoeae. It is inactivated by beta-lactamases, so not helpful for Staphylococcus.



atropine - Correct Answers-muscinarinic receptor antagonist/anticholinergic drug; used for
mydriases (eye exams), to raise HR, lower GI motility, and as antidote to muscarinic poisoning
(rx, shrooms)

,amphotericin B - Correct Answers-broad spectrum antifungal, which is the agent of choice for
systemic mycoses, despite being highly toxic. Its uses are limited to treating progressive and
potentially fatal infections. Adverse effects include infusion reactions, nephrotoxicity, and
hypokalemia.



aspirin - Correct Answers-A drug that decrease platelet aggregation and is used to prevent
arterial thrombosis, stroke, or MI. Major SEs include risk of major GI bleeding. This drug is an
NSAID that works by inhibiting platelet COX, COX-1, and COX-2.



beclomethasone - Correct Answers-inhaled corticosteroid used to treat airway inflammation in
asthma



bethanechol - Correct Answers-muscarinic agnonist, used primarily for urinary retention



buproprion - Correct Answers-(DA and NE). Weight loss, seizure, insomnia, headache, serotonin
syndrome (see laundry list above), withdrawal, Neonatal Abstinence Syndrome



captopril - Correct Answers-ACE inhibitor - shown to have efficacious effects in treating a patient
with heart failure. Blocks production of angiotensin II, dilates arterioles and veins, and
decreases release of aldosterone. It may show the adverse effects of hypotension,
hyperkalemia, or persistant cough, CARDIAC REMODELING



carbenicillin - Correct Answers-"Extended spectrum (antipseudomonal penicillins), which has
the same spectrum of activity as broad-spectrum penicillins, plus treatment of Pseudomonas
aeruginosa



cefotaxime - Correct Answers-"Third generation cephalosporin with activity against meningitis
and nosocomial infections resistant to others (restricted use). It has greater activity against
Gram negative bacteria, increased resistance to beta-lactamases, and better ability to reach CSF.

, cephalexin - Correct Answers-"First generation cephalosporin poor activity against Gram
negative bacteria, sensitive to to most beta-lactamases, unable to reach CSF. Used for
Staphylococcus if mild penicillin allergy.



celecoxib - Correct Answers-2nd Generation Nonsteroidal Antiinflammatory Drug (COX-2
Selective NSAID); AE: risk of CV events, warfarin may be more effective with celecoxib



cholestyramine - Correct Answers-Inhibits bile reabsorption in intenstine, increases LDL
receptors in liver, accelerates bile excretion. Many of the adverse effects result from the drug
not being absorbed from GI, including constipation and a decreased absorption of fat-soluble
vitamins (A, D, E, & K).



ciprofloxacin - Correct Answers-fluoroquinolone

broad -cidal. PO tetracycline and cipro should NOT BE GIVEN WITH ANTACIDS.

ALSO KNOW IT CAN RUPTURE TENDONS AND CAUSE CANDIDA. "



codeine - Correct Answers-antitussive, AE: respiratory depression

also weak mu opioid agonist



clozapine - Correct Answers-atypical antipsychotic; 2nd Gen. Treats negative symptoms. Greater
efficacy than 1st gen. Fewer EPS/tardive dyskinesia side effects. SE: Agranulocytosis and
Metabolic effects (Weight gain, diabetes, hyperlipidemia)



clonidine - Correct Answers-alpha 2 agonist, HTN drug -> vasodilation



clavulanic acid - Correct Answers-A penicillinase inhibitor that is combined with a broad
spectrum penicillin to increase is bactericidal activity.

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