CNPR EXAMS SCRIPT 2025/2026 QUESTIONS WITH
ANSWERS RATED A+
✔✔Smoking decreases the effectiveness of some drugs. - ✔✔True
✔✔Because dietary supplements are not drugs, interactions with drugs are not a
concern. - ✔✔False
✔✔Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. - ✔✔True
✔✔What is the difference between resistance and tolerance? - ✔✔Tolerance refers to a
person's diminished response to a drug after repeated use, while resistance applies to
microorganism's or cancer cell's abilities to withstand drug effects.
✔✔Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. - ✔✔True
✔✔There is no universal scale for quantifying the severity of an adverse drug reaction. -
✔✔True
✔✔Why is noncompliance a serious public health concern? - ✔✔It increases the cost of
medical care.
✔✔Name 3 items available for which patent protection is available under U.S.
regulations. - ✔✔The drug itself, the method of delivering and releasing the drug into
the bloodstream, and the way the drug is made.
✔✔Drugs' trade names are often unrelated to their intended use. - ✔✔False
✔✔Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - ✔✔False
✔✔Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - ✔✔20
✔✔Biologics do not cause immune responses. - ✔✔False
✔✔"Large molecule" products are developed and manufactured by a chemical process.
- ✔✔False
✔✔What are the drugs that attract or bind cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - ✔✔Agonists
,✔✔What term denotes how an API works in the body? - ✔✔Mechanism of action.
✔✔What cements the active and inert components together to maintain cohesive
portions? - ✔✔Binders.
✔✔What does the abbreviation BID denote? - ✔✔Twice a day
✔✔What is the medical abbreviation for 'as needed'? - ✔✔PRN.
✔✔Which components might cause patient's different reactions to brand name and
generic drugs? - ✔✔Differences in inactive ingredients.
✔✔All cells have a nucleus. - ✔✔False
✔✔Name three things that affect drug response. - ✔✔The patient's genetic makeup,
age, body size, and use of other drugs and dietary supplements. The patient's other
conditions and diseases. Whether or not the patient takes the drug properly.
✔✔Drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions. -
✔✔False
✔✔What is the typical relationship between a drug's site of administration and site of
action? - ✔✔They are usually somewhat removed from one another.
✔✔What is CMAX? - ✔✔The peak plasma concentration on a measuring curve.
✔✔Pharmacoprocesses are a main concept of clinical pharmacology. - ✔✔False
✔✔Which is not a route of drug administration - buccal, intramuscular, sublingual, or
transfugal? - ✔✔Transfugal
✔✔How are intradermal drugs delivered? - ✔✔By injection under the skin.
✔✔An injection of anesthetic directly into the bloodstream is an example of intravenous
drug delivery. - ✔✔True
✔✔What are the major organs of the gastrointestinal system? - ✔✔The mouth,
esophagus, stomach, liver, pancreas, gallbladder, small and large intestines.
✔✔Who is normally responsible for selling to distributors? - ✔✔NAMs.
, ✔✔How often do secondary drugs wholesale distributors buy their drugs directly from
manufacturers? - ✔✔Sometimes
✔✔By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufacturers. - ✔✔False
✔✔Only 3 companies account for nearly 90% of all wholesale drug sales. - ✔✔True
✔✔What type of sale bypasses the need for intermediary distributors? -
✔✔Manufacturer direct sales.
✔✔What is a group purchasing organization (GPO)? - ✔✔An entity consisting of two or
more hospitals or other health care entities that negotiates contracts on behalf of its
members.
✔✔Prescriptions dispensed by mail-order pharmacies are, on average, around _______
than those dispensed by retail pharmacies. - ✔✔3 times larger
✔✔Which of the following is NOT a type of non-stock sale -
a) brokerage sales
b) dock-to-dock sales
c) drop shipments
d) all of these are types of non-stock sales - ✔✔D) all of these are types of non-stock
sales
✔✔What is another term for rebates? - ✔✔After market arrangements.
✔✔The PDMA is the Prescription Drug Manufacturers Association. - ✔✔False.
✔✔A company that owns and operates three or fewer pharmacies is an
_______________. - ✔✔Independent drug store.
✔✔Which section of a drug's package insert information covers the usual dosage
range? - ✔✔Indications and usage.
✔✔Drug labels must include indications, usage information, and contraindications. -
✔✔True
✔✔What should be included in the description section of a drug's package insert
information? - ✔✔The drug's proprietary name and the established name.
✔✔Exclusivity gives exclusive ___________, is granted by the FDA, and can run
concurrently with a patent or not. - ✔✔Marketing rights.
ANSWERS RATED A+
✔✔Smoking decreases the effectiveness of some drugs. - ✔✔True
✔✔Because dietary supplements are not drugs, interactions with drugs are not a
concern. - ✔✔False
✔✔Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. - ✔✔True
✔✔What is the difference between resistance and tolerance? - ✔✔Tolerance refers to a
person's diminished response to a drug after repeated use, while resistance applies to
microorganism's or cancer cell's abilities to withstand drug effects.
✔✔Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. - ✔✔True
✔✔There is no universal scale for quantifying the severity of an adverse drug reaction. -
✔✔True
✔✔Why is noncompliance a serious public health concern? - ✔✔It increases the cost of
medical care.
✔✔Name 3 items available for which patent protection is available under U.S.
regulations. - ✔✔The drug itself, the method of delivering and releasing the drug into
the bloodstream, and the way the drug is made.
✔✔Drugs' trade names are often unrelated to their intended use. - ✔✔False
✔✔Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - ✔✔False
✔✔Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - ✔✔20
✔✔Biologics do not cause immune responses. - ✔✔False
✔✔"Large molecule" products are developed and manufactured by a chemical process.
- ✔✔False
✔✔What are the drugs that attract or bind cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - ✔✔Agonists
,✔✔What term denotes how an API works in the body? - ✔✔Mechanism of action.
✔✔What cements the active and inert components together to maintain cohesive
portions? - ✔✔Binders.
✔✔What does the abbreviation BID denote? - ✔✔Twice a day
✔✔What is the medical abbreviation for 'as needed'? - ✔✔PRN.
✔✔Which components might cause patient's different reactions to brand name and
generic drugs? - ✔✔Differences in inactive ingredients.
✔✔All cells have a nucleus. - ✔✔False
✔✔Name three things that affect drug response. - ✔✔The patient's genetic makeup,
age, body size, and use of other drugs and dietary supplements. The patient's other
conditions and diseases. Whether or not the patient takes the drug properly.
✔✔Drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions. -
✔✔False
✔✔What is the typical relationship between a drug's site of administration and site of
action? - ✔✔They are usually somewhat removed from one another.
✔✔What is CMAX? - ✔✔The peak plasma concentration on a measuring curve.
✔✔Pharmacoprocesses are a main concept of clinical pharmacology. - ✔✔False
✔✔Which is not a route of drug administration - buccal, intramuscular, sublingual, or
transfugal? - ✔✔Transfugal
✔✔How are intradermal drugs delivered? - ✔✔By injection under the skin.
✔✔An injection of anesthetic directly into the bloodstream is an example of intravenous
drug delivery. - ✔✔True
✔✔What are the major organs of the gastrointestinal system? - ✔✔The mouth,
esophagus, stomach, liver, pancreas, gallbladder, small and large intestines.
✔✔Who is normally responsible for selling to distributors? - ✔✔NAMs.
, ✔✔How often do secondary drugs wholesale distributors buy their drugs directly from
manufacturers? - ✔✔Sometimes
✔✔By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufacturers. - ✔✔False
✔✔Only 3 companies account for nearly 90% of all wholesale drug sales. - ✔✔True
✔✔What type of sale bypasses the need for intermediary distributors? -
✔✔Manufacturer direct sales.
✔✔What is a group purchasing organization (GPO)? - ✔✔An entity consisting of two or
more hospitals or other health care entities that negotiates contracts on behalf of its
members.
✔✔Prescriptions dispensed by mail-order pharmacies are, on average, around _______
than those dispensed by retail pharmacies. - ✔✔3 times larger
✔✔Which of the following is NOT a type of non-stock sale -
a) brokerage sales
b) dock-to-dock sales
c) drop shipments
d) all of these are types of non-stock sales - ✔✔D) all of these are types of non-stock
sales
✔✔What is another term for rebates? - ✔✔After market arrangements.
✔✔The PDMA is the Prescription Drug Manufacturers Association. - ✔✔False.
✔✔A company that owns and operates three or fewer pharmacies is an
_______________. - ✔✔Independent drug store.
✔✔Which section of a drug's package insert information covers the usual dosage
range? - ✔✔Indications and usage.
✔✔Drug labels must include indications, usage information, and contraindications. -
✔✔True
✔✔What should be included in the description section of a drug's package insert
information? - ✔✔The drug's proprietary name and the established name.
✔✔Exclusivity gives exclusive ___________, is granted by the FDA, and can run
concurrently with a patent or not. - ✔✔Marketing rights.
