BCHM 4360 EXAM 2 (ACTUAL EXAM 2025) | ALL QUESTIONS AND
BCHM 4360 Exam II
CORRECT ANSWERS | VERIFIED ANSWERS | GRADED A+ | NEWEST
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EXAM (JUST RELEASED)
1. What are the three initiation, elongation, termination
steps of transcrip-
tion?
2. True or False: The False, replication bubble is much larger because it requires two machines at
transcription bub- once.
ble is just as big as
the replication bub-
ble.
3. When does tran- when RNA Polymerase binds to the promoter
scription officially
start?
4. What is the first the transcription start site (TSS) and +1
base to be tran-
scribed known as
and how is it denot-
ed?
5. Which direction is 5' to 3'
RNA transcribed in?
6. On RNA, bases 3' of downstream, upstream
a site are __________
while bases 5' of a
site are _________.
7. When the RNA promoter, conformation
is a sufficient
size, the RNA
Polymerase moves
past the ________
, BCHM 4360 Exam II
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and changes
____________ to be
more stably associ-
ated with the DNA.
8. How does the RNA unwinds the DNA ahead of the bubble and the DNA re-pairs behind the
Polymerase main- enzyme
tain the transcrip-
tion bubble along
the DNA?
9. Elongation contin- terminator
ues until the
polymerase meets
a DNA sequence
called a __________.
10. What are the three 1. Nucleosome remodeling enzymes
additional types of 2. Histone chaperones
enzymes besides 3. Enzymes that reversibly modify histone proteins
RNA Polymerase
that are required
in eukaryotic tran-
scription?
11. What does RNA large rRNA genes
Polymerase I typi-
cally transcribe?
12. What does RNA mRNA genes
Polymerase II typi-
cally transcribe?
, BCHM 4360 Exam II
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13. What does RNA tRNA and 5S rRNA
Polymerase III typi-
cally transcribe?
14. True or False: False, bacteria and archaea only have a single RNA Polymerase.
Bacteria and ar-
chaea have multi-
ple RNA Polymeras-
es just like eukary-
otes, they just have
different kinds.
15. True or False: All True
RNA Polymerases
have a core enzyme
that catalyzes RNA
synthesis, but this
cannot act alone
and relies on extra
proteins.
16. Bacteria are _______ simpler, sigma
than eukaryotes
and thus operate
mainly on _____ fac-
tors.
17. Which domain has Bacteria, 400kD
the smallest RNA
Polymerase and ap-
proximately what
size is it?
, BCHM 4360 Exam II
Study online at https://quizlet.com/_hdjahn
18. How many sub- 5
units are in the
bacterial RNA Poly-
merase?
19. What shape do bac- jaw-like lobes
terial RNA Poly-
merase subunits
assemble into?
20. Between Pol I, II, Rbp5, 6, 8, 10, and 12
and III, which sub-
units are common?
21. What is an addition- couples transcription to processing of RNA transcript
al function of RNA
Polymerase II?
22. True or False: RNA True
core sequences can
synthesize RNA,
but cannot recog-
nize promoter se-
quences.
23. What does the core Sigma factor
bacterial enzyme
require in order to
recognize promot-
er sequences?
24. holoenzyme
BCHM 4360 Exam II
CORRECT ANSWERS | VERIFIED ANSWERS | GRADED A+ | NEWEST
Study online at https://quizlet.com/_hdjahn
EXAM (JUST RELEASED)
1. What are the three initiation, elongation, termination
steps of transcrip-
tion?
2. True or False: The False, replication bubble is much larger because it requires two machines at
transcription bub- once.
ble is just as big as
the replication bub-
ble.
3. When does tran- when RNA Polymerase binds to the promoter
scription officially
start?
4. What is the first the transcription start site (TSS) and +1
base to be tran-
scribed known as
and how is it denot-
ed?
5. Which direction is 5' to 3'
RNA transcribed in?
6. On RNA, bases 3' of downstream, upstream
a site are __________
while bases 5' of a
site are _________.
7. When the RNA promoter, conformation
is a sufficient
size, the RNA
Polymerase moves
past the ________
, BCHM 4360 Exam II
Study online at https://quizlet.com/_hdjahn
and changes
____________ to be
more stably associ-
ated with the DNA.
8. How does the RNA unwinds the DNA ahead of the bubble and the DNA re-pairs behind the
Polymerase main- enzyme
tain the transcrip-
tion bubble along
the DNA?
9. Elongation contin- terminator
ues until the
polymerase meets
a DNA sequence
called a __________.
10. What are the three 1. Nucleosome remodeling enzymes
additional types of 2. Histone chaperones
enzymes besides 3. Enzymes that reversibly modify histone proteins
RNA Polymerase
that are required
in eukaryotic tran-
scription?
11. What does RNA large rRNA genes
Polymerase I typi-
cally transcribe?
12. What does RNA mRNA genes
Polymerase II typi-
cally transcribe?
, BCHM 4360 Exam II
Study online at https://quizlet.com/_hdjahn
13. What does RNA tRNA and 5S rRNA
Polymerase III typi-
cally transcribe?
14. True or False: False, bacteria and archaea only have a single RNA Polymerase.
Bacteria and ar-
chaea have multi-
ple RNA Polymeras-
es just like eukary-
otes, they just have
different kinds.
15. True or False: All True
RNA Polymerases
have a core enzyme
that catalyzes RNA
synthesis, but this
cannot act alone
and relies on extra
proteins.
16. Bacteria are _______ simpler, sigma
than eukaryotes
and thus operate
mainly on _____ fac-
tors.
17. Which domain has Bacteria, 400kD
the smallest RNA
Polymerase and ap-
proximately what
size is it?
, BCHM 4360 Exam II
Study online at https://quizlet.com/_hdjahn
18. How many sub- 5
units are in the
bacterial RNA Poly-
merase?
19. What shape do bac- jaw-like lobes
terial RNA Poly-
merase subunits
assemble into?
20. Between Pol I, II, Rbp5, 6, 8, 10, and 12
and III, which sub-
units are common?
21. What is an addition- couples transcription to processing of RNA transcript
al function of RNA
Polymerase II?
22. True or False: RNA True
core sequences can
synthesize RNA,
but cannot recog-
nize promoter se-
quences.
23. What does the core Sigma factor
bacterial enzyme
require in order to
recognize promot-
er sequences?
24. holoenzyme
