BIO 340 - Exam 2 - Questions with Verified Answers| Latest Update Graded A+
Loss-of-function mutations cause a gene to lose some or all of its normal function
Hypomorphic mutations are those that have lost only some of their function
Null mutations have lost all of their function
Haplosufficient one (haplo) copy is sufficient to produce the wild-type phenotype in the
heterozygous genotype
Haploinsufficient a single copy is not sufficient to produce the wild-type phenotype in the
heterozygous genotype
Gain-of-function in which the gene product acquires a new function or express increased
wild type activity
Incomplete dominance The phenotype of the heterozygote is intermediate between those
of the two homozygotes, on some
quantitative scale (color, size, ex. pink)
Codominance The phenotype of both alleles is fully expressed in the
heterozygote (ex red and white)
Complementation tests determine if mutations are in same gene
Epistatic interactions when two or more genes affect the same phenotype, by influencing a
common pathway
Loss-of-function mutations cause a gene to lose some or all of its normal function
Hypomorphic mutations are those that have lost only some of their function
Null mutations have lost all of their function
Haplosufficient one (haplo) copy is sufficient to produce the wild-type phenotype in the
heterozygous genotype
Haploinsufficient a single copy is not sufficient to produce the wild-type phenotype in the
heterozygous genotype
Gain-of-function in which the gene product acquires a new function or express increased
wild type activity
Incomplete dominance The phenotype of the heterozygote is intermediate between those
of the two homozygotes, on some
quantitative scale (color, size, ex. pink)
Codominance The phenotype of both alleles is fully expressed in the
heterozygote (ex red and white)
Complementation tests determine if mutations are in same gene
Epistatic interactions when two or more genes affect the same phenotype, by influencing a
common pathway
