CORRECT ANSWERS DEATILED
RATIONALES WITH RELEVANT
REFERENCES
A 25-year-old patient is being treated with temozolomide. The
patient is instructed to:
take the medication at bedtime on an empty stomach.
divide the medication doses over 24 hours.
consume a magnesium supplement with the medication.
ingest the medication with a full glass of milk. Correct Answer
take the medication at bedtime on an empty stomach.
Answer: Patients are to be instructed to take temozolomide
on an empty stomach at bedtime to decrease the risk of
nausea and vomiting.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.).
(2014). Chemotherapy and biotherapy guidelines and
recommendations for practice (4th ed.). Pittsburgh, PA: Oncology
Nursing Society, p. 31(t).
,Which of the following chemotherapy orders should the nurse
question?
Intrathecal vincristine
Intramuscular asparaginase
Intraperitoneal cisplatin
Subcutaneous bortezomib Correct Answer Intrathecal vincristine
Answer: Vincristine is fatal if administered intrathecally.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.).
(2014). Chemotherapy and biotherapy guidelines and
recommendations for practice (4th ed.). Pittsburgh, PA: Oncology
Nursing Society, p. 47(t).
Which of the following conditions will most likely be treated by an
allogeneic stem cell transplant?
Chronic myeloid leukemia
Hodgkin lymphoma
Multiple myeloma
Follicular thyroid cancer Correct Answer Chronic myeloid
leukemia
,Answer: Chronic myeloid leukemia is most likely to be treated by
an allogeneic transplant.
Reference: Yarbro, C.H., Wujcik, D., & Gobel, B.H. (Eds.). (2018).
Cancer nursing: Principles and practice (8th ed.). Burlington, MA:
Jones and Bartlett, p. 563(t).
When does nadir typically occur after the completion of a
chemotherapy treatment cycle?
7 - 10 days
5 weeks
3 weeks
1 - 3 days Correct Answer 7 - 10 days
Answer: Nadir varies, but typically occurs 7-10 days after
chemotherapy.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.).
(2014). Chemotherapy and biotherapy guidelines and
recommendations for practice (4th ed.). Pittsburgh, PA: Oncology
Nursing Society, pp. 171-172.
, Myeloablative conditioning for stem cell transplantation includes:
high-dose chemotherapy.
a nutritional analysis.
a retrograde surgical intervention.
a fitness evaluation. Correct Answer high-dose chemotherapy.
Answer: Administration of high-dose chemotherapy helps
eliminate residual disease prior to a hematopoietic stem cell
transplant.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.).
(2014). Chemotherapy and biotherapy guidelines and
recommendations for practice (4th ed.). Pittsburgh, PA: Oncology
Nursing Society, p. 5.
Information about which of the following side effects should be
provided to a patient being treated with posaconazole?
Torsades de Pointes
Pancreatitis
Toxic epidermal necrolysis
Aplastic anemia Correct Answer Torsades de Pointes