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USMLE STEP 1 Pharmacology Full Study-Guide / Actual Exam Questions Bank with Definitive Explanations of Answers / Newest 2025/2026.

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USMLE STEP 1 Pharmacology Full Study-Guide / Actual Exam Questions Bank with Definitive Explanations of Answers / Newest 2025/2026. Terms in this set (870) Quiz____? What are the major functions of the α1 receptor? - Answer Increase vascular smooth muscle contraction, increase pupillary dilator muscle contraction (mydriasis), increase intestinal and bladder sphincter muscle contraction Quiz____? What are the major functions of the α2 receptor? - Answer Decrease sympathetic outflow, decrease insulin release, decrease lipolysis, increase platelet aggregation, decrease aqueous humor production Quiz____? What are the major functions of the β1 receptor? - Answer Increase heart rate, increase contractility, increase renin release, increase lipolysis

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Terms in this set (870)

Quiz____?

What are the major functions of the α1 receptor? -

Answer✓✓

Increase vascular smooth muscle contraction, increase pupillary dilator muscle contraction

(mydriasis), increase intestinal and bladder sphincter muscle contraction




Quiz____?

What are the major functions of the α2 receptor? -

Answer✓✓

Decrease sympathetic outflow, decrease insulin release, decrease lipolysis, increase platelet

aggregation, decrease aqueous humor production




Quiz____?

What are the major functions of the β1 receptor? -



1

, Answer✓✓

Increase heart rate, increase contractility, increase renin release, increase lipolysis




Quiz____?

What are the major functions of the β2 receptor? -

Answer✓✓

Vasodilation, bronchodilation, increase lipolysis, increase insulin release, decrease uterine tone

(tocolysis), ciliary muscle relaxation, increase aqueous humor production




Quiz____?

What are the major functions of the M1 receptor? -

Answer✓✓

CNS, enteric nervous system




Quiz____?

What are the major functions of the M2 receptor? -

Answer✓✓

Decrease heart rate and contractility of atria




2

, Quiz____?

What are the major functions of the M3 receptor? -

Answer✓✓

Increase exocrine gland secretions (e.g., lacrimal, salivary, gastric acid), increase gut peristalsis,

increase bladder contraction, increase bronchoconstriction, pupillary sphincter muscle

contraction (miosis), ciliary muscle contraction (accommodation)




Quiz____?

What are the major functions of the D1 receptor? -

Answer✓✓

Relaxes renal vascular smooth muscle




Quiz____?

What are the major functions of the D2 receptor? -

Answer✓✓

Modulates transmitter release, especially in the brain




Quiz____?

What are the major functions of the H1 receptor? -

Answer✓✓


3

, Increase nasal and bronchial mucus production, increase vascular permeability, contraction of

bronchioles, pruritis, pain




Quiz____?

What are the major functions of the H2 receptor? -

Answer✓✓

Increase gastric acid secretion




Quiz____?

What are the major functions of the V1 receptor? -

Answer✓✓

Increase vascular smooth muscle contraction




Quiz____?

What are the major functions of the V2 receptor? -

Answer✓✓

Increase H2O permeability and reabsorption in collecting tubules of kidney (V2 is found in the

"2" kidneys)




4

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