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CPHON Certification – 2025/2026 Pediatric Oncology Nurse Practice Questions with Correct Answers and Rationales

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This document provides a comprehensive collection of expertly curated practice questions and correct answers designed for the 2025/2026 Certified Pediatric Hematology Oncology Nurse (CPHON) exam. It covers essential pediatric oncology nursing topics including chemotherapy effects, disease-specific nursing care, psychosocial support, hematologic disorders, pain management, and patient education. Complete with clinical rationales, this resource is ideal for mastering exam content and reinforcing real-world knowledge.

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CPHON: Practice Test Questions
2025/2026 Exam All Answers and
Illustrations Given



Which of the following is an indication that a child is experiencing

precocious puberty?




A-Testicular enlargement at age 10

B-Tall stature

C-Delayed epiphyseal fusion


D-Advanced bone age - 🧠 ANSWER ✔✔D-advanced bone age




--when child's body changes into adult's body too soon

-age 10 is normal age to start puberty; would be a sign if <10

Parental grief following the death of a child from cancer generally plateau's

at what point in time?

COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER:
619652435. TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 1

, A- 4 -10 months

B- 12 - 18 months

C- 20 - 26 months


D- 30 - 36 months - 🧠 ANSWER ✔✔B- 12-18mo


The parent of a 7-year-old child with end-stage disease asks the nurse, "My

child has been asking questions about death, what do I say?" What would

be the most appropriate response from the nurse?




A- Tell the patient that it is like a special sleep

B- Suggest that the parent be genuine and sincere

C- Ask a trained professional to talk with the parent

D- Explain that the child is too young to understand death - 🧠 ANSWER

✔✔B- suggest that the parents be genuine and sincere


Phantom limb pain following a surgical amputation is an example of what

type of pain?

A- Somatic

COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER:
619652435. TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 2

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