6/14/25, 10:07 AM NURS 8024 Pharm Exam 3 (antimicrobial part 2) 2025 COMPLETE QUESTIONS With 100% Verified Solutions, Flashcards | Quizlet
NURS 8024 Pharm Exam 3 (antimicrobial part 2)
2025 COMPLETE QUESTIONS With 100% Verified
Solutions,
Save
Terms in this set (58)
Bacterial protein synthesis Clindamycin
inhibitors
Time dependent killing
Inhibits protein synthesis
Clindamycin
Bacteriostatic
90% bioavailability
Clindamycin mechanism Altered target sites
of resistance Active efflux (pushes drug out of the cell)
GI upset
Skin rash
Clindamycin ADE Neutropenia
Superinfections such a c diff pseudomembranous
- don't use if patient has history of c diff
Gram positive
Clindamycin indications Prophylaxis of endocarditis in valve patients with PCN
allergy
https://quizlet.com/1054182656/nurs-8024-pharm-exam-3-antimicrobial-part-2-2025-complete-questions-with-100-verified-solutions-flash-cards/ 1/8
, 6/14/25, 10:07 AM NURS 8024 Pharm Exam 3 (antimicrobial part 2) 2025 COMPLETE QUESTIONS With 100% Verified Solutions, Flashcards | Quizlet
New class of bacterial protein synthesis inhibitors
Oxazolidinones Time dependent killing
Prevents formation of ribosome complex
Bacteriostatic & Bactericidal against strep
Protein synthesis inhibitor
Linezolid 100% bioavailability orally
30% CSF penetration
Hematologic
Increased thrombocytopenia risk
Linezolid ADE Anemia, neutropenia, neuropathy
Optic & peripheral neuropathy
Serotonin syndrome with SSRIs
Gram positive resistant
VRE, HCAP, CAP
Linezolid Indications Complicated skin & tissue infections
Off label use for TB
No resistance currently
Norfloxacin (1st gen)
Ciprofloxacin & Ofloxacin (2nd gen)
Fluoroquinolones
Levofloxacin (3rd gen)
Moxifloxacin & Gemifloxacin (3rd gen respiratory)
Fluoroquinolones are Generations according to antimicrobial spectra
classified by
1st Generation Narrow gram negative
Fluoroquinolone Norfloxacin
2nd Generation Broad- gram negative and gram positive
Fluoroquinolone Cipro & ofloxacin
More gram positive than gram negative
Levofloxacin
3rd generation
Moxifloxacin
Fluoroquinolone
Gemifloxacin
-moxi and gemi are respiratory Fluoroquinolones
https://quizlet.com/1054182656/nurs-8024-pharm-exam-3-antimicrobial-part-2-2025-complete-questions-with-100-verified-solutions-flash-cards/ 2/8
NURS 8024 Pharm Exam 3 (antimicrobial part 2)
2025 COMPLETE QUESTIONS With 100% Verified
Solutions,
Save
Terms in this set (58)
Bacterial protein synthesis Clindamycin
inhibitors
Time dependent killing
Inhibits protein synthesis
Clindamycin
Bacteriostatic
90% bioavailability
Clindamycin mechanism Altered target sites
of resistance Active efflux (pushes drug out of the cell)
GI upset
Skin rash
Clindamycin ADE Neutropenia
Superinfections such a c diff pseudomembranous
- don't use if patient has history of c diff
Gram positive
Clindamycin indications Prophylaxis of endocarditis in valve patients with PCN
allergy
https://quizlet.com/1054182656/nurs-8024-pharm-exam-3-antimicrobial-part-2-2025-complete-questions-with-100-verified-solutions-flash-cards/ 1/8
, 6/14/25, 10:07 AM NURS 8024 Pharm Exam 3 (antimicrobial part 2) 2025 COMPLETE QUESTIONS With 100% Verified Solutions, Flashcards | Quizlet
New class of bacterial protein synthesis inhibitors
Oxazolidinones Time dependent killing
Prevents formation of ribosome complex
Bacteriostatic & Bactericidal against strep
Protein synthesis inhibitor
Linezolid 100% bioavailability orally
30% CSF penetration
Hematologic
Increased thrombocytopenia risk
Linezolid ADE Anemia, neutropenia, neuropathy
Optic & peripheral neuropathy
Serotonin syndrome with SSRIs
Gram positive resistant
VRE, HCAP, CAP
Linezolid Indications Complicated skin & tissue infections
Off label use for TB
No resistance currently
Norfloxacin (1st gen)
Ciprofloxacin & Ofloxacin (2nd gen)
Fluoroquinolones
Levofloxacin (3rd gen)
Moxifloxacin & Gemifloxacin (3rd gen respiratory)
Fluoroquinolones are Generations according to antimicrobial spectra
classified by
1st Generation Narrow gram negative
Fluoroquinolone Norfloxacin
2nd Generation Broad- gram negative and gram positive
Fluoroquinolone Cipro & ofloxacin
More gram positive than gram negative
Levofloxacin
3rd generation
Moxifloxacin
Fluoroquinolone
Gemifloxacin
-moxi and gemi are respiratory Fluoroquinolones
https://quizlet.com/1054182656/nurs-8024-pharm-exam-3-antimicrobial-part-2-2025-complete-questions-with-100-verified-solutions-flash-cards/ 2/8
