Exam 5: Advanced Concepts in Obesity Prevention and
Treatment
Energy Balance Basics - correct answer ✔✔Adults generally need between 1,500 and 3,500 kcal
per day, depending on their size and activity levels.
Carbohydrates = 4 kcal per gram
Protein = 4 kcal per gram
Fat = 9 kcal per gram
Alcohol = 7 kcal per gram
Maintaining a Healthy Weight is a Balancing Act - correct answer ✔✔Calories In = Calories Out
How long will you have to walk in order to burn those extra 305 calories?* - correct answer
✔✔If you walk 1 hour and 20 minutes, you will burn approximately 305 calories.*
How many calories are in today's chicken Caesar salad? - correct answer ✔✔790 calories
3 ½ cups
Calorie Difference: 400 calories
How long will you have to walk the dog in order to burn those extra 400 calories?* - correct
answer ✔✔If you walk the dog for 1 hour and 20 minutes, you will burn approximately 400
calories.*
Intro to Pharmaceutical Approaches - correct answer ✔✔Induce only modest weight loss
compared to placebo.
Maintenance of lower weight is difficult and generally requires continued treatmen
, Targets of drugs used for obesity treatment - correct answer ✔✔Decrease food intake
Decrease energy absorption
Increase Physical Activity
Increase Basal Metabolic Rate
The history of pharmaceutical treatment include several drugs no longer used because risk
outweighed the benefits. (phen-fen)
Principles for Using Obesity Medications - correct answer ✔✔Obesity medications used alone
have only small effects on weight. They are most helpful for supporting behavioral approaches
to weight loss as adjuncts to lifestyle changes.
Medications approved by the FDA for long term use are appropriate for subjects with BMI of 30
or more. (27 or more if comorbidities.)
*Due to associated risks and side-effects and since they do not result in large weight loss, they
should not be used for cosmetic weight loss.
Benefits of Modest Weight Loss - correct answer ✔✔Blood pressure, blood lipid levels, and
control of blood glucose may all be improved with as little as 5-10% weight loss. (Sleep apnea
and arthritis were also improved).
A 7% weight loss in subjects with impaired glucose tolerance test was associated with a 58%
reduction in risk for development of type 2 diabetes.
Drugs Approved by the FDA for Long-term Treatment of Overweight - correct answer
✔✔Orlistat (Xenical, Alli)
Inhibits breakdown and absorption of dietary fat.
Treatment
Energy Balance Basics - correct answer ✔✔Adults generally need between 1,500 and 3,500 kcal
per day, depending on their size and activity levels.
Carbohydrates = 4 kcal per gram
Protein = 4 kcal per gram
Fat = 9 kcal per gram
Alcohol = 7 kcal per gram
Maintaining a Healthy Weight is a Balancing Act - correct answer ✔✔Calories In = Calories Out
How long will you have to walk in order to burn those extra 305 calories?* - correct answer
✔✔If you walk 1 hour and 20 minutes, you will burn approximately 305 calories.*
How many calories are in today's chicken Caesar salad? - correct answer ✔✔790 calories
3 ½ cups
Calorie Difference: 400 calories
How long will you have to walk the dog in order to burn those extra 400 calories?* - correct
answer ✔✔If you walk the dog for 1 hour and 20 minutes, you will burn approximately 400
calories.*
Intro to Pharmaceutical Approaches - correct answer ✔✔Induce only modest weight loss
compared to placebo.
Maintenance of lower weight is difficult and generally requires continued treatmen
, Targets of drugs used for obesity treatment - correct answer ✔✔Decrease food intake
Decrease energy absorption
Increase Physical Activity
Increase Basal Metabolic Rate
The history of pharmaceutical treatment include several drugs no longer used because risk
outweighed the benefits. (phen-fen)
Principles for Using Obesity Medications - correct answer ✔✔Obesity medications used alone
have only small effects on weight. They are most helpful for supporting behavioral approaches
to weight loss as adjuncts to lifestyle changes.
Medications approved by the FDA for long term use are appropriate for subjects with BMI of 30
or more. (27 or more if comorbidities.)
*Due to associated risks and side-effects and since they do not result in large weight loss, they
should not be used for cosmetic weight loss.
Benefits of Modest Weight Loss - correct answer ✔✔Blood pressure, blood lipid levels, and
control of blood glucose may all be improved with as little as 5-10% weight loss. (Sleep apnea
and arthritis were also improved).
A 7% weight loss in subjects with impaired glucose tolerance test was associated with a 58%
reduction in risk for development of type 2 diabetes.
Drugs Approved by the FDA for Long-term Treatment of Overweight - correct answer
✔✔Orlistat (Xenical, Alli)
Inhibits breakdown and absorption of dietary fat.