TEST BANK f
PATHOPHYSIOLOGY - THE BIOLOGIC BASIS FOR DISEASE
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f IN ADULTS AND CHILDREN
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8th Edition
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Kathryn L. McCance, Sue E. Huether
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, 2
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Contents
Chapter 01: Cellular Biology .......................................................................................................................... 4
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Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents .................................................... 18
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Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases ....................................... 31
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Chapter 04: Genes and Genetic Diseases .................................................................................................... 44
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Chapter 05: Genes, Environment-Lifestyle, and Common Diseases............................................................ 55
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Chapter 06: Epigenetics and Disease........................................................................................................... 63
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Chapter 07: Innate Immunity: Inflammation and Wound Healing .............................................................. 68
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Chapter 08: Adaptive Immunity .................................................................................................................. 83
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Chapter 09: Alterations in Immunity and Inflammation.............................................................................. 95
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Chapter 10: Infection................................................................................................................................. 108
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Chapter 11: Stress and Disease ................................................................................................................. 117
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Chapter 12: Cancer Biology ....................................................................................................................... 124
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Chapter 13: Cancer Epidemiology ............................................................................................................. 137
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Chapter 14: Cancer in Children .................................................................................................................. 143
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Chapter 15: Structure and Function of the Neurologic System ................................................................. 148
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Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ................................................ 159
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Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ................. 174
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Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
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..................................................................................................................................................................188 f
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ............................. 199
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Chapter 20: Alterations of Neurologic Function in Children ...................................................................... 206
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Chapter 21: Mechanisms of Hormonal Regulation.................................................................................... 213
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Chapter 22: Alterations of Hormonal Regulation ...................................................................................... 222
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Chapter 23: Obesity and Disorders of Nutrition ........................................................................................ 234
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Chapter 24: Structure and Function of the Reproductive Systems............................................................ 239
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Chapter 25: Alterations of the Female Reproductive System.................................................................... 249
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Chapter 26: Alterations of the Male Reproductive System ....................................................................... 259
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Chapter 27: Sexually Transmitted Infections............................................................................................. 265
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Chapter 28: Structure and Function of the Hematologic System .............................................................. 273
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Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function........................................... 283
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Chapter 30: Alterations of Leukocyte and Lymphoid Function.................................................................. 293
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Chapter 31: Alterations of Hematologic Function in Children ................................................................... 300
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Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ................................. 311
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Chapter 33: Alterations of Cardiovascular Function .................................................................................. 324
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Chapter 34: Alterations of Cardiovascular Function in Children ................................................................ 338
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Chapter 35: Structure and Function of the Pulmonary System ................................................................. 346
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Chapter 36: Alterations of Pulmonary Function ........................................................................................ 356
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Chapter 37: Alterations of Pulmonary Function in Children ...................................................................... 373
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Chapter 38: Structure and Function of the Renal and Urologic Systems ................................................... 381
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Chapter 39: Alterations of Renal and Urinary Tract Function .................................................................... 391
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Chapter 40: Alterations of Renal and Urinary Tract Function in Children .................................................. 401
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Chapter 41: Structure and Function of the Digestive System .................................................................... 409
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Chapter 42: Alterations of Digestive Function ........................................................................................... 421
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Chapter 43: Alterations of Digestive Function in Children ......................................................................... 432
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Chapter 44: Structure and Function of the Musculoskeletal System......................................................... 441
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Chapter 45: Alterations of Musculoskeletal Function ............................................................................... 453
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Chapter 46: Alterations of Musculoskeletal Function in Children ............................................................. 466
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Chapter 47: Structure, Function, and Disorders of the Integument .......................................................... 475
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Chapter 48: Alterations of the Integument in Children ............................................................................. 486
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Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults...................................... 494
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Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children .................................. 502
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, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th)
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Chapter 01: Cellular Biology
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MULTIPLE CHOICE f
1. Which statement best describes the cellular function of metabolic absorption?
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a. Cells can produce proteins. f f f
b. Cells can secrete digestive enzymes.
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c. Cells can take in and use nutrients.
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d. Cells can synthesize fats. f f f
ANS: C f
In metabolic absorption, all cells take in and use nutrients and other substances from their
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surroundings. The remaining options are not inclusive in their descriptions of cellular
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metabolicabsorption.
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PTS: 1 ff f DIF: Cognitive Level: Remembering f f
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C f
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most
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ofthe cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its
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activity. The mitochondria are responsible for cellular respiration and energy production.
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Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes
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functionas the intracellular digestive system.
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PTS: 1 ff f DIF: Cognitive Level: Remembering f f
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to
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f removehydrogen atoms from specific substrates in an oxidative reaction?
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a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B f
PATHOPHYSIOLOGY - THE BIOLOGIC BASIS FOR DISEASE
f f f f f f
f IN ADULTS AND CHILDREN
f f f
8th Edition
f
Kathryn L. McCance, Sue E. Huether
f f f f f
, 2
fff
Contents
Chapter 01: Cellular Biology .......................................................................................................................... 4
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Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents .................................................... 18
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Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases ....................................... 31
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Chapter 04: Genes and Genetic Diseases .................................................................................................... 44
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Chapter 05: Genes, Environment-Lifestyle, and Common Diseases............................................................ 55
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Chapter 06: Epigenetics and Disease........................................................................................................... 63
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Chapter 07: Innate Immunity: Inflammation and Wound Healing .............................................................. 68
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Chapter 08: Adaptive Immunity .................................................................................................................. 83
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Chapter 09: Alterations in Immunity and Inflammation.............................................................................. 95
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Chapter 10: Infection................................................................................................................................. 108
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Chapter 11: Stress and Disease ................................................................................................................. 117
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Chapter 12: Cancer Biology ....................................................................................................................... 124
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Chapter 13: Cancer Epidemiology ............................................................................................................. 137
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Chapter 14: Cancer in Children .................................................................................................................. 143
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Chapter 15: Structure and Function of the Neurologic System ................................................................. 148
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Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ................................................ 159
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Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ................. 174
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Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
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..................................................................................................................................................................188 f
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ............................. 199
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Chapter 20: Alterations of Neurologic Function in Children ...................................................................... 206
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Chapter 21: Mechanisms of Hormonal Regulation.................................................................................... 213
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Chapter 22: Alterations of Hormonal Regulation ...................................................................................... 222
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Chapter 23: Obesity and Disorders of Nutrition ........................................................................................ 234
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Chapter 24: Structure and Function of the Reproductive Systems............................................................ 239
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Chapter 25: Alterations of the Female Reproductive System.................................................................... 249
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Chapter 26: Alterations of the Male Reproductive System ....................................................................... 259
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Chapter 27: Sexually Transmitted Infections............................................................................................. 265
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Chapter 28: Structure and Function of the Hematologic System .............................................................. 273
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Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function........................................... 283
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, 3
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Chapter 30: Alterations of Leukocyte and Lymphoid Function.................................................................. 293
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Chapter 31: Alterations of Hematologic Function in Children ................................................................... 300
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Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ................................. 311
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Chapter 33: Alterations of Cardiovascular Function .................................................................................. 324
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Chapter 34: Alterations of Cardiovascular Function in Children ................................................................ 338
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Chapter 35: Structure and Function of the Pulmonary System ................................................................. 346
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Chapter 36: Alterations of Pulmonary Function ........................................................................................ 356
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Chapter 37: Alterations of Pulmonary Function in Children ...................................................................... 373
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Chapter 38: Structure and Function of the Renal and Urologic Systems ................................................... 381
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Chapter 39: Alterations of Renal and Urinary Tract Function .................................................................... 391
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Chapter 40: Alterations of Renal and Urinary Tract Function in Children .................................................. 401
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Chapter 41: Structure and Function of the Digestive System .................................................................... 409
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Chapter 42: Alterations of Digestive Function ........................................................................................... 421
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Chapter 43: Alterations of Digestive Function in Children ......................................................................... 432
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Chapter 44: Structure and Function of the Musculoskeletal System......................................................... 441
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Chapter 45: Alterations of Musculoskeletal Function ............................................................................... 453
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Chapter 46: Alterations of Musculoskeletal Function in Children ............................................................. 466
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Chapter 47: Structure, Function, and Disorders of the Integument .......................................................... 475
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Chapter 48: Alterations of the Integument in Children ............................................................................. 486
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Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults...................................... 494
f f f f f f f f f f
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children .................................. 502
f f f f f f f f f f
, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th)
f f f f f f f f f f f f f ffff f 4
Chapter 01: Cellular Biology
f f f
MULTIPLE CHOICE f
1. Which statement best describes the cellular function of metabolic absorption?
f f f f f f f f f
a. Cells can produce proteins. f f f
b. Cells can secrete digestive enzymes.
f f f f
c. Cells can take in and use nutrients.
f f f f f f
d. Cells can synthesize fats. f f f
ANS: C f
In metabolic absorption, all cells take in and use nutrients and other substances from their
f f f f f f f f f f f f f f
surroundings. The remaining options are not inclusive in their descriptions of cellular
f f f f f f f f f f f f
metabolicabsorption.
f f
PTS: 1 ff f DIF: Cognitive Level: Remembering f f
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
f f f f f f f f f f f f
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C f
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most
f f f f f f f f f f f f f
ofthe cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its
f f f f f f f f f f f f f f f
activity. The mitochondria are responsible for cellular respiration and energy production.
f f f f f f f f f f f
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes
f f f f f f f f f f f
functionas the intracellular digestive system.
f f f f f f
PTS: 1 ff f DIF: Cognitive Level: Remembering f f
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to
f f f f f f f f f f f f
f removehydrogen atoms from specific substrates in an oxidative reaction?
f f f f f f f f f
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B f
