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NRSG 245 - Final Exam Questions And All Correct Answers.

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patient sensitivity to drugs related to age - Answer sensitivity goes up as age goes up, they will feel greater effects drug calculations conversions - Answer 100 mcg = 1 mg, 100 mg = 1 g, 100 mL = 1 L, drug calculations for children - Answer use body surface area 24 hour clock/military time - Answer a method of telling time that assigns a number to each hour of the day polypharmacy - Answer the use of multiple medications on a regular basis teratogenic - Answer known to have potential to cause developmental defects in the embryo or fetus therapeutic index - Answer the ratio between the toxic and therapeutic concentrations of a drug large vs small therapeutic index - Answer the larger a therapeutic index is, the safer the drug is, the smaller a therapeutic index is, the more risk for toxicity there is first pass effect - Answer the initial metabolism in the liver of a drug absorbed from the GI tract before the drug reaches systemic circulation through the bloodstream preload - Answer volume of blood in ventricles at end of diastole, veins going into heart afterload - Answer the amount of resistance to ejection of blood leaving the ventricle, arteries tolerance - Answer the tendency for larger doses of a drug to be required over time to achieve the same effect pharmacogenomics - Answer the study of how genetic inheritance affects the body's response to drugs

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NRSG 245 - Final Exam Questions And
All Correct Answers.

patient sensitivity to drugs related to age - Answer sensitivity goes up as age goes up, they will
feel greater effects



drug calculations conversions - Answer 100 mcg = 1 mg, 100 mg = 1 g, 100 mL = 1 L,



drug calculations for children - Answer use body surface area



24 hour clock/military time - Answer a method of telling time that assigns a number to each
hour of the day



polypharmacy - Answer the use of multiple medications on a regular basis



teratogenic - Answer known to have potential to cause developmental defects in the embryo
or fetus



therapeutic index - Answer the ratio between the toxic and therapeutic concentrations of a
drug



large vs small therapeutic index - Answer the larger a therapeutic index is, the safer the drug
is, the smaller a therapeutic index is, the more risk for toxicity there is



first pass effect - Answer the initial metabolism in the liver of a drug absorbed from the GI
tract before the drug reaches systemic circulation through the bloodstream



preload - Answer volume of blood in ventricles at end of diastole, veins going into heart



afterload - Answer the amount of resistance to ejection of blood leaving the ventricle, arteries



tolerance - Answer the tendency for larger doses of a drug to be required over time to achieve
the same effect

, physical dependance - Answer a type of addiction in which the body itself feels a direct need
for a drug



ideal properties of a drug - Answer effectiveness, safety, selectivity, reversible action,
predictability, ease of administration, no drug interactions, low cost, chemical stability, simple
generic name



3 most important properties of a drug - Answer effectiveness, safety, selectivity



pharmokinetic properties - Answer absorption, distribution, metabolism, excretion



absorption - Answer the movement of a drug from its site of administration into the blood



distribution - Answer drug movement from the blood to the interstitial space of tissues and
from there into the cells



metabolism - Answer "biotransformation" enzyme mediated alteration of drug structure



excretion - Answer movement of drugs and metabolites out of the body



rights of safe medication administration - Answer client, medication, dose, time, route,
documentation, client education, refuse, assessment, and evaluation



beer's list - Answer a list of drugs for which monitoring is especially important in elderly
patients



patient teaching for taking a drug on an empty stomach - Answer don't eat 1 hour before you
eat and wait for 2 hours after you eat



importance of handwashing - Answer effective hand washing reduces the spread of
pathogenic microbes



enteric coating - Answer coating on meds that allow it to be dissolved in the small intestine
instead of stomach

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