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MCB2010 Exam 2 Questions with Complete Solutions 100% Solved| Grade A+

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MCB2010 Exam 2 Questions with Complete Solutions 100% Solved| Grade A+

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MCB2010 Exam 2 Questions with Complete Solutions 100% Solved| Grade A+
T cell subclass differentiation allows T cell clones to recognize different epitopes of the same
antigen. (t/F) FALSE



Required for t-cell activation MHC I or II
Involvement of CD4 or CD8
Bound antigen



the cellular branch of adaptive immunity is organized by T helper cells and carried out by T
cytotoxic cells.



B cells Coordinate the humoral response by making antibodies.
Originate and mature in the bone marrow.



t-cells originate in bone marrow, but mature in thymus
reside in lymphoid tissue
have capacitiy to recognize virtually any type of antigen.



branches of adaptive immunity humoral and cellular



humoral branch of adaptive immunity -Involves antibodies (made by B cells)
-Defends against extracellular pathogens



Three phases of inflammation vascular changes, leukocyte recruitment, and resolution


Main goals: Transport chemical factors essential for tissue recovery. Limit the spread of
infectious agents. Recruit immune defenses to the injured tissue.

,molecular second line defenses Cytokines, iron-binding proteins, complement proteins


FX: Leukocytes are recruited to the site of infection, triggering fever and stimulating
inflammation.



Gonorrhoeae circumvents our iron-sequestering defenses by Capturing iron-binding
proteins and pulling the iron out for their own use


Dendritic cells prevent the immune system from attacking the self and from over-reacting to
nonthreatening substances. (t/F) true



The spleen is a primary lymphoid tissue. (T/F) FALSE



What role do erythrocytes play in our blood? deliver oxygen



What is edema tissue swelling



What are the two categories of second-line defenses? Assorted molecular factors and
leukocytes



what is the most important physical barrier skin



antimicrobial peptides disrupt pathogen plasma membranes


produced by leukocytes



enzyme lysozyme Catalyzes lysis (breaking) of bacterial cells

, acts as a chemical barrier
kills bacterial cells
can be found in mucus, saliva, tears, and breast milk



mechanical barrier separates two of the body's fluid compartments


ex.the mucociliary escalator



benefits of our normal microbiota - compete for nutrients with pathogens
- compete for space with pathogens
- make substances that may directly damage pathogens
- generate an environment that limits pathogen survival



Adaptive immunity the ability to recognize and remember specific antigens and mount an
attack on them


only in vertebrate animals
mature over time
evolved more recently



most common portal of entry for human pathogens respiratory tract



Pathogens can obtain iron from the body using siderophores



Which portal of exit will a bloodborne pathogen likely use? parenteral



A microbe with a low ID50 does not necessarily cause severe disease. true

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