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CHEMOTHERAPY CERTIFICATION 2025/2026 ANSWERS AND QUESTIONS GRADED A+

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CHEMOTHERAPY CERTIFICATION 2025/2026 ANSWERS AND QUESTIONS GRADED A+

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CHEMOTHERAPY CERTIFICATION 2025/2026 ANSWERS
AND QUESTIONS GRADED A+
✔✔ Doxorubicin - ✔✔Cardiotoxic
TISSUE VESICANT
Baseline MUGA and total dose (CONCERN at 550 mg/m2)
URINE=RED
IF EXTRAVASATION OCCURS= cool/ice + Totect

✔✔Idamycin - ✔✔Cardiotoxic (cardiomyopathy)

✔✔Bleomycin - ✔✔AVOID oxygen supplementation

✔✔Methotrexate - ✔✔*Leukovorin decreases cytotoxicity*

✔✔Pemetrexed - ✔✔Vitamin B12 & folic acid supplements to decrease toxicity

✔✔Fludarabine - ✔✔Immunosuppression

✔✔Thioguanine - ✔✔Bone Marrow Suppression
Stomatitis/Mucositis

✔✔5-FU - ✔✔*Stomatitis
Bone marrow depression
*Diarrhea
Mucositis

✔✔Capeticibine - ✔✔***Pro-drug that converts 5FU in liver
Stomatitis & mucositis
Palmar-plantar erythrodysthesias (hand foot syndrome)

✔✔Cytarabine or Cytosine Arabinoside - ✔✔Cerebellar neurotoxicity

✔✔Gemcitabine - ✔✔Radiosensitizer DO NOT GIVE W/ RADIATION, except at very
low doses

✔✔Carmustine - ✔✔***Solvent is alcohol
Alcohol sensivity is an issue
Mix ONLY in 0.9% NaCl

✔✔Carboplatin - ✔✔Dose by CALVERT formula
Allergic reaction increased from 1-27% in pts receiving >6-7 courses

✔✔Cisplatin - ✔✔Renal toxicity

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