sbb final Exam 2025|Actual Exam
Test(MULTIPLE CHOICES) and
(RATIONALES) questions and verified
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Terms in this set (98)
,A peripheral C. Hemolytic anemia
smear with
increased Megaloblastic anemia would show
polychromasia, larger, less mature RBCs on the smear.
schistocytes and Iron deficiency anemia would show
spherocytes is hypochromasia, and a lower RBC count.
indicative of which Aplastic anemia would show very little
condition? amounts of mature RBCs on the smear
Hemolytic anemia results in misshapen
A. Aplastic anemia RBCs and inconsistent RBC appearance
B. Iron deficiency because of the rapid RBC destruction.
anemia Because the RBCs have as shortened
C. Hemolytic survival, pieces of the membrance can
anemia break off resulting in spherocytes and
D. Megaloblastic schistocytes.
anemia
, Answer: Dithiothreitol (DTT)
LW antigens require divalent cations
(e.g., Mg2+) for expression and have
intramolecular disulfide bonds that are
sensitive to dithiothreitol (DTT)
treatment.
DTT treatment is helpful to differentiate
anti-LW from anti-D, because the D
Which of the
antigen is resistant to DTT while LW
following
antigen is sensitive to DTT.
treatments is
LW antigens are expressed equally well
useful when
on group O D-positive and D-negative
distinguishing
cord blood red cell.
between anti-D
expected reaction with O- cord
and anti-Lw?
RBCsexpected reaction with O+ DTT
treated RBCsanti-LW+-anti-D-+
A. Choloroquine
B. Cord cells
The best answer is DTT.
C. Ficin
Cord cells are not considered a
D. Dithiothreitol
treatment and often used in conjunction
with DTT results to confirm the
presence of either antibody.
ficin (breaks down proteins) and
chloroquine (dissociates bound
antibody from RBCs/ destroys HLA
antigens) do not disrupt disulfide
bonds
, bonds.
Correct: Circulating Immune Complexes
Plasma exchange is used to help a
temporary condition. So an autoimmune
disease is better treated with the use of
steroids and other medicines that will
suppress the autoantibody production.
Therapeutic
A patient with high titer anti-D is actively
plasma exchange
producing anti-D. So these patients will
is most useful in
also not benefit from plasma exchange
treating patients
since their immune system is just going
with:
to produce more anti-D.
Patients with hyperimmune syndromes
A. Circulating
are also actively producing harmful
immune
substances, so removing them won't be
complexes
effective since more will be produced
B. Autoimmune
as soon as the procedure is completed.
diseases
Circulating immune complexes are a
C. high titer IgG
condition that is caused by antigen-
anti-D
antibody reaction due to a short lived
D. Hyperimmune
condition, so the use of plasma
synromes
exchange is very effective in removing
those large complexes. With additional
treatment, we can prevent more
immune complexes from forming so
once the exchange is complete, the
condition is most often resolved.
Test(MULTIPLE CHOICES) and
(RATIONALES) questions and verified
answers |GET IT 100% ACCURATE!!
Save
Terms in this set (98)
,A peripheral C. Hemolytic anemia
smear with
increased Megaloblastic anemia would show
polychromasia, larger, less mature RBCs on the smear.
schistocytes and Iron deficiency anemia would show
spherocytes is hypochromasia, and a lower RBC count.
indicative of which Aplastic anemia would show very little
condition? amounts of mature RBCs on the smear
Hemolytic anemia results in misshapen
A. Aplastic anemia RBCs and inconsistent RBC appearance
B. Iron deficiency because of the rapid RBC destruction.
anemia Because the RBCs have as shortened
C. Hemolytic survival, pieces of the membrance can
anemia break off resulting in spherocytes and
D. Megaloblastic schistocytes.
anemia
, Answer: Dithiothreitol (DTT)
LW antigens require divalent cations
(e.g., Mg2+) for expression and have
intramolecular disulfide bonds that are
sensitive to dithiothreitol (DTT)
treatment.
DTT treatment is helpful to differentiate
anti-LW from anti-D, because the D
Which of the
antigen is resistant to DTT while LW
following
antigen is sensitive to DTT.
treatments is
LW antigens are expressed equally well
useful when
on group O D-positive and D-negative
distinguishing
cord blood red cell.
between anti-D
expected reaction with O- cord
and anti-Lw?
RBCsexpected reaction with O+ DTT
treated RBCsanti-LW+-anti-D-+
A. Choloroquine
B. Cord cells
The best answer is DTT.
C. Ficin
Cord cells are not considered a
D. Dithiothreitol
treatment and often used in conjunction
with DTT results to confirm the
presence of either antibody.
ficin (breaks down proteins) and
chloroquine (dissociates bound
antibody from RBCs/ destroys HLA
antigens) do not disrupt disulfide
bonds
, bonds.
Correct: Circulating Immune Complexes
Plasma exchange is used to help a
temporary condition. So an autoimmune
disease is better treated with the use of
steroids and other medicines that will
suppress the autoantibody production.
Therapeutic
A patient with high titer anti-D is actively
plasma exchange
producing anti-D. So these patients will
is most useful in
also not benefit from plasma exchange
treating patients
since their immune system is just going
with:
to produce more anti-D.
Patients with hyperimmune syndromes
A. Circulating
are also actively producing harmful
immune
substances, so removing them won't be
complexes
effective since more will be produced
B. Autoimmune
as soon as the procedure is completed.
diseases
Circulating immune complexes are a
C. high titer IgG
condition that is caused by antigen-
anti-D
antibody reaction due to a short lived
D. Hyperimmune
condition, so the use of plasma
synromes
exchange is very effective in removing
those large complexes. With additional
treatment, we can prevent more
immune complexes from forming so
once the exchange is complete, the
condition is most often resolved.
