TEST BANK FOR
gv gv
Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
gv gv gv gv gv gv gv gv gv gv gv
Chapter 1-27
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,Chapter 01: Highlights of the Innate and Adaptive Immune Systems
gv gv gv gv gv gv gv gv gv
MULTIPLE CHOICE gv
1. The ―father‖ of immunology is generally considered to be
gv gv gv gv gv gv gv gv
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: g v B
Louis Pasteur is generally considered to be the ―father of immunology.‖
gv gv gv gv gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
2. An early form of immunization was practiced by the
gv gv gv gv gv gv gv gv
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. gv
ANS: g v C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
powders derived from the crusts of smallpox lesions.
gv gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
3. A gv specific function of the immune system is to
gv gv gv gv gv gv gv
a. recognize self from nonself. gv gv gv
b. defend the body against nonself. gv gv gv gv
c. amplify specific functions. gv gv
d. Both A and B. gv gv gv
ANS: g v D
The function of the immune system is to recognize self from nonself and defend the body ag
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ainst nonself. Such a system is necessary for survival. The immune system also has nonspec
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ific effector mechanisms that usually amplify the specific functions. Nonspecific component
gv gv gv gv gv gv gv gv gv gv
s of the immune system include mononuclear phagocytes, polymorphonuclear leukocytes, an
gv gv gv gv gv gv gv gv gv gv
d soluble factors (e.g., complement).
gv gv gv gv
DIF: Cognitive Level: I gv gv
4. An undesirable consequence of immunity is
gv gv gv gv gv
a. natural resistance. gv
b. acquired resistance to infectious diseases. gv gv gv gv
, c. an autoimmune disorder.gv gv
d. recovery from infectious disease. gv gv gv
ANS: g v C
The desirable consequences of immunity include natural resistance, recovery, and acquired r
gv gv gv gv gv gv gv gv gv gv gv
esistance to infectious diseases. A deficiency or dysfunction of the immune system can cause
gv gv gv gv gv gv gv gv gv gv gv gv gv
many disorders. Undesirable consequences of immunity include allergy, rejection of a trans
gv gv gv gv gv gv gv gv gv gv gv gv
planted organ, or an autoimmune disorder.
gv gv gv gv gv
DIF: Cognitive Level: I gv gv
5. The immune system has various distinctive characteristics except;
gv gv gv gv gv gv gv
a. specificity.
b. memory.
c. mobility.
d. noncooperation among different cells. gv gv gv
ANS: g v D
The immune system is composed of a large, complex set of widely distributed elements, wit
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
h the distinctive characteristics of specificity, memory, mobility, replicability, and cooperati
gv gv gv gv gv gv gv gv gv gv
on among different cells or cellular products. Specificity and memory are characteristics of l
gv gv gv gv gv gv gv gv gv gv gv gv gv
ymphocytes in the immune system. Nonspecific elements of the immune system demonstrate
gv gv gv gv gv gv gv gv gv gv gv g
mobility. In addition, specific and nonspecific cellular components of the immune system ca
v gv gv gv gv gv gv gv gv gv gv gv gv
n replicate. Cooperation is required for optimal functioning, and interaction involves specifi
gv gv gv gv gv gv gv gv gv gv gv
c cellular elements, cell products, and nonlymphoid elements.
gv gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
6. Hematopoiesis occurs in the yolk sac during the gv gv gv gv gv gv gv
a. immediate hours after conception gv gv gv
b. second month of gestation. gv gv gv
c. second trimester of gestation. gv gv gv
d. periods of severe anemia in children. gv gv gv gv gv
ANS: g v A
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the em
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
bryo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestation.
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
DIF: Cognitive Level: II gv gv
7. The sequence of blood cell development in the embryo and fetus is
gv gv gv gv gv gv gv gv gv gv gv
a. yolk sac, liver-spleen, bone marrow.
gv gv gv gv
b. yolk sac, bone marrow, liver/spleen.
gv gv gv gv
c. liver-spleen, yolk sac, bone marrow. gv gv gv gv
d. bone marrow, liver-spleen, yolk sac.
gv gv gv gv
ANS: g v A
, The first blood cells are primitive red blood cells (erythroblasts; RBCs) formed in the islets
gv gv gv gv gv gv gv gv gv gv gv gv gv gv g
vof the yolk sac during the first 2 to 8 weeks of life. Gradually, the liver and spleen replace
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
gvthe yolk sac as the sites of blood cell development. By the second month of gestation, the
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv g
vliver becomes the major site of hematopoiesis, and granular types of leukocytes have mad
gv gv gv gv gv gv gv gv gv gv gv gv gv
e their initial appearance. The liver and spleen predominate from about 2 to 5 months of fe
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
tal life. In the fourth month of gestation, bone marrow begins to produce blood cells. After
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
the fifth fetal month, bone marrow begins to assume its ultimate role as the primary site of
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv g
vhematopoiesis.
DIF: Cognitive Level: II gv gv
8. The primary function of mature neutrophils is
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a. to reduce inflammation.
gv gv
b. to lyse parasites in the circulatory system.
gv gv gv gv gv gv
c. antigen recognition. gv
d. phagocytosis.
ANS: g v D
Various phagocytic cells continually circulate throughout the blood, lymph, gastrointestinal
gv gv gv gv gv gv gv gv gv gv
system, and respiratory tract. When trauma occurs, the neutrophils arrive at the site of injur
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
y and can be found in the initial exudate in less than 1 hour. Monocytes are slower in movi
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ng to the inflammatory site. Macrophages resident in the tissues of the body are already in
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
place to deal with an intruding agent. Additional macrophages from the bone marrow and ot
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
her tissues can be released in severe infections.
gv gv gv gv gv gv gv
DIF: Cognitive Level: II gv gv
9. Primary granules, or azurophilic granules, in neutrophils contain
gv gv gv gv gv gv gv
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both A and B. gv gv gv
ANS: g v D
Granules in the phagocyte cytosol contain degradatory enzymes of three types
gv gv gv gv gv gv gv gv gv gv
1. Primary, or azurophilic, granules containing enzymes (e.g., lysozyme gv gv gv gv gv gv gv
, myeloperoxidase) gv
2. Secondary, or specific, granules containing substances such as lactoferrin. gv gv gv gv gv gv gv gv
3. Tertiary granules containing substances such as caspases gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
10. The origin of a condition when eosinophils are increased in the circulating blood is associa
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ted with: gv
a. fungus
b. parasitic amoeba gv
c. allergic reactions gv
d. bacteria
ANS: g v C
gv gv
Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
gv gv gv gv gv gv gv gv gv gv gv
Chapter 1-27
gv
,Chapter 01: Highlights of the Innate and Adaptive Immune Systems
gv gv gv gv gv gv gv gv gv
MULTIPLE CHOICE gv
1. The ―father‖ of immunology is generally considered to be
gv gv gv gv gv gv gv gv
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: g v B
Louis Pasteur is generally considered to be the ―father of immunology.‖
gv gv gv gv gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
2. An early form of immunization was practiced by the
gv gv gv gv gv gv gv gv
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. gv
ANS: g v C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
powders derived from the crusts of smallpox lesions.
gv gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
3. A gv specific function of the immune system is to
gv gv gv gv gv gv gv
a. recognize self from nonself. gv gv gv
b. defend the body against nonself. gv gv gv gv
c. amplify specific functions. gv gv
d. Both A and B. gv gv gv
ANS: g v D
The function of the immune system is to recognize self from nonself and defend the body ag
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ainst nonself. Such a system is necessary for survival. The immune system also has nonspec
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ific effector mechanisms that usually amplify the specific functions. Nonspecific component
gv gv gv gv gv gv gv gv gv gv
s of the immune system include mononuclear phagocytes, polymorphonuclear leukocytes, an
gv gv gv gv gv gv gv gv gv gv
d soluble factors (e.g., complement).
gv gv gv gv
DIF: Cognitive Level: I gv gv
4. An undesirable consequence of immunity is
gv gv gv gv gv
a. natural resistance. gv
b. acquired resistance to infectious diseases. gv gv gv gv
, c. an autoimmune disorder.gv gv
d. recovery from infectious disease. gv gv gv
ANS: g v C
The desirable consequences of immunity include natural resistance, recovery, and acquired r
gv gv gv gv gv gv gv gv gv gv gv
esistance to infectious diseases. A deficiency or dysfunction of the immune system can cause
gv gv gv gv gv gv gv gv gv gv gv gv gv
many disorders. Undesirable consequences of immunity include allergy, rejection of a trans
gv gv gv gv gv gv gv gv gv gv gv gv
planted organ, or an autoimmune disorder.
gv gv gv gv gv
DIF: Cognitive Level: I gv gv
5. The immune system has various distinctive characteristics except;
gv gv gv gv gv gv gv
a. specificity.
b. memory.
c. mobility.
d. noncooperation among different cells. gv gv gv
ANS: g v D
The immune system is composed of a large, complex set of widely distributed elements, wit
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
h the distinctive characteristics of specificity, memory, mobility, replicability, and cooperati
gv gv gv gv gv gv gv gv gv gv
on among different cells or cellular products. Specificity and memory are characteristics of l
gv gv gv gv gv gv gv gv gv gv gv gv gv
ymphocytes in the immune system. Nonspecific elements of the immune system demonstrate
gv gv gv gv gv gv gv gv gv gv gv g
mobility. In addition, specific and nonspecific cellular components of the immune system ca
v gv gv gv gv gv gv gv gv gv gv gv gv
n replicate. Cooperation is required for optimal functioning, and interaction involves specifi
gv gv gv gv gv gv gv gv gv gv gv
c cellular elements, cell products, and nonlymphoid elements.
gv gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
6. Hematopoiesis occurs in the yolk sac during the gv gv gv gv gv gv gv
a. immediate hours after conception gv gv gv
b. second month of gestation. gv gv gv
c. second trimester of gestation. gv gv gv
d. periods of severe anemia in children. gv gv gv gv gv
ANS: g v A
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the em
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
bryo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestation.
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
DIF: Cognitive Level: II gv gv
7. The sequence of blood cell development in the embryo and fetus is
gv gv gv gv gv gv gv gv gv gv gv
a. yolk sac, liver-spleen, bone marrow.
gv gv gv gv
b. yolk sac, bone marrow, liver/spleen.
gv gv gv gv
c. liver-spleen, yolk sac, bone marrow. gv gv gv gv
d. bone marrow, liver-spleen, yolk sac.
gv gv gv gv
ANS: g v A
, The first blood cells are primitive red blood cells (erythroblasts; RBCs) formed in the islets
gv gv gv gv gv gv gv gv gv gv gv gv gv gv g
vof the yolk sac during the first 2 to 8 weeks of life. Gradually, the liver and spleen replace
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
gvthe yolk sac as the sites of blood cell development. By the second month of gestation, the
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv g
vliver becomes the major site of hematopoiesis, and granular types of leukocytes have mad
gv gv gv gv gv gv gv gv gv gv gv gv gv
e their initial appearance. The liver and spleen predominate from about 2 to 5 months of fe
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
tal life. In the fourth month of gestation, bone marrow begins to produce blood cells. After
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
the fifth fetal month, bone marrow begins to assume its ultimate role as the primary site of
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv g
vhematopoiesis.
DIF: Cognitive Level: II gv gv
8. The primary function of mature neutrophils is
gv gv gv gv gv gv
a. to reduce inflammation.
gv gv
b. to lyse parasites in the circulatory system.
gv gv gv gv gv gv
c. antigen recognition. gv
d. phagocytosis.
ANS: g v D
Various phagocytic cells continually circulate throughout the blood, lymph, gastrointestinal
gv gv gv gv gv gv gv gv gv gv
system, and respiratory tract. When trauma occurs, the neutrophils arrive at the site of injur
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
y and can be found in the initial exudate in less than 1 hour. Monocytes are slower in movi
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ng to the inflammatory site. Macrophages resident in the tissues of the body are already in
gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv gv
place to deal with an intruding agent. Additional macrophages from the bone marrow and ot
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
her tissues can be released in severe infections.
gv gv gv gv gv gv gv
DIF: Cognitive Level: II gv gv
9. Primary granules, or azurophilic granules, in neutrophils contain
gv gv gv gv gv gv gv
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both A and B. gv gv gv
ANS: g v D
Granules in the phagocyte cytosol contain degradatory enzymes of three types
gv gv gv gv gv gv gv gv gv gv
1. Primary, or azurophilic, granules containing enzymes (e.g., lysozyme gv gv gv gv gv gv gv
, myeloperoxidase) gv
2. Secondary, or specific, granules containing substances such as lactoferrin. gv gv gv gv gv gv gv gv
3. Tertiary granules containing substances such as caspases gv gv gv gv gv gv
DIF: Cognitive Level: I gv gv
10. The origin of a condition when eosinophils are increased in the circulating blood is associa
gv gv gv gv gv gv gv gv gv gv gv gv gv gv
ted with: gv
a. fungus
b. parasitic amoeba gv
c. allergic reactions gv
d. bacteria
ANS: g v C
