Please check the examination details below before entering your candidate information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel International Advanced Level
Tuesday 8 October 2024
Morning (Time: 1 hour 30 minutes) Paper
reference WBI11/01
Biology
International Advanced Subsidiary/Advanced Level
UNIT 1: Molecules, Diet, Transport and Health
You must have: Total Marks
Scientific calculator, ruler, HB pencil
Instructions
• Use black ink or ball‑point pen.
• centrethe
Fill in boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• – there may
Answer the questions in the spaces provided
be more space than you need.
• You must show allbe your
Calculators may used.
• end of your solution. working out with your answer clearly identified at the
Information
• The total mark for this paper is 80.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
• structure
In questions marked with an asterisk (*), marks will be awarded for your ability to
your answer logically, showing how the points you make are related or
follow on from each other where appropriate.
Advice
• Read each question carefully before you start to answer it.
• Checkanswer
Try to every question.
• your answers if you have time at the end. Turn over
P78384A
©2024 Pearson Education Ltd.
V:1/1/1/1/
*P78384A0132*
, Answer ALL questions. Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you change your mind about an
DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA
answer, put a line through the box and then mark your new answer with a cross .
1 Amoeba are single‑celled organisms that live in water. They are able to change
their shape.
The diagram shows two different shapes that one amoeba can make.
Shape 1 Shape 2 cell membrane
nucleus
cytoplasm
300 μm
(a) An amoeba changes shape by pushing cytoplasm against the cell membrane,
forming long thin projections.
State the property of the cell membrane that enables the amoeba to
change shape.
(1)
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
(b) Gas exchange in an amoeba takes place across its cell membrane.
(i) The amoeba can be roughly spherical, as shown in Shape 1.
Which is the surface area of the amoeba in this shape?
Use the formula:
surface area of a sphere = 4πr 2
(1)
A 90 000π µm2
B 90 000π µm3
C 360 000π µm2
D 360 000π µm3
2
*P78384A0232*
, (ii) The mass of the amoeba stays the same when it changes from Shape 1
to Shape 2.
DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA
Which row of the table shows what happens to the surface area and volume
of this amoeba when it changes to Shape 2?
(1)
surface area volume
A decreases decreases
B increases increases
C increases stays the same
D stays the same stays the same
(iii) Explain why an amoeba can rely on diffusion to supply the oxygen it needs.
(2)
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
(Total for Question 1 = 5 marks)
3
*P78384A0332* Turn over
, 2 During the development of a human, the structure of haemoglobin changes.
In the developing fetus the main oxygen‑carrying molecule is fetal haemoglobin.
DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA
Towards the end of fetal development, fetal haemoglobin is replaced by adult forms
of haemoglobin.
(a) Blood may contain 5.3 million red blood cells in 1 mm3 of blood.
One red blood cell can contain 270 million haemoglobin molecules.
Calculate the number of haemoglobin molecules in 1 mm3 of blood.
Express your answer in standard form.
(1)
Answer ........................................ . . . . . . . . . . . . . . . . . . . . . .
(b) Which of the following statements about the structure of haemoglobin
are correct?
1. It is a fibrous protein
2. It has quaternary structure
3. It contains a non‑protein haem group
(1)
A 1 only
B 3 only
C 1 and 2 only
D 2 and 3 only
4
*P78384A0432*
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel International Advanced Level
Tuesday 8 October 2024
Morning (Time: 1 hour 30 minutes) Paper
reference WBI11/01
Biology
International Advanced Subsidiary/Advanced Level
UNIT 1: Molecules, Diet, Transport and Health
You must have: Total Marks
Scientific calculator, ruler, HB pencil
Instructions
• Use black ink or ball‑point pen.
• centrethe
Fill in boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• – there may
Answer the questions in the spaces provided
be more space than you need.
• You must show allbe your
Calculators may used.
• end of your solution. working out with your answer clearly identified at the
Information
• The total mark for this paper is 80.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
• structure
In questions marked with an asterisk (*), marks will be awarded for your ability to
your answer logically, showing how the points you make are related or
follow on from each other where appropriate.
Advice
• Read each question carefully before you start to answer it.
• Checkanswer
Try to every question.
• your answers if you have time at the end. Turn over
P78384A
©2024 Pearson Education Ltd.
V:1/1/1/1/
*P78384A0132*
, Answer ALL questions. Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you change your mind about an
DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA
answer, put a line through the box and then mark your new answer with a cross .
1 Amoeba are single‑celled organisms that live in water. They are able to change
their shape.
The diagram shows two different shapes that one amoeba can make.
Shape 1 Shape 2 cell membrane
nucleus
cytoplasm
300 μm
(a) An amoeba changes shape by pushing cytoplasm against the cell membrane,
forming long thin projections.
State the property of the cell membrane that enables the amoeba to
change shape.
(1)
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
(b) Gas exchange in an amoeba takes place across its cell membrane.
(i) The amoeba can be roughly spherical, as shown in Shape 1.
Which is the surface area of the amoeba in this shape?
Use the formula:
surface area of a sphere = 4πr 2
(1)
A 90 000π µm2
B 90 000π µm3
C 360 000π µm2
D 360 000π µm3
2
*P78384A0232*
, (ii) The mass of the amoeba stays the same when it changes from Shape 1
to Shape 2.
DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA
Which row of the table shows what happens to the surface area and volume
of this amoeba when it changes to Shape 2?
(1)
surface area volume
A decreases decreases
B increases increases
C increases stays the same
D stays the same stays the same
(iii) Explain why an amoeba can rely on diffusion to supply the oxygen it needs.
(2)
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . .. .. .. .. .. .. .. .. .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ............................................................................................................................................ ................ . . . . . . . . . . . . . . . . . . . .
(Total for Question 1 = 5 marks)
3
*P78384A0332* Turn over
, 2 During the development of a human, the structure of haemoglobin changes.
In the developing fetus the main oxygen‑carrying molecule is fetal haemoglobin.
DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA DO NOT WRITE IN THIS AREA
Towards the end of fetal development, fetal haemoglobin is replaced by adult forms
of haemoglobin.
(a) Blood may contain 5.3 million red blood cells in 1 mm3 of blood.
One red blood cell can contain 270 million haemoglobin molecules.
Calculate the number of haemoglobin molecules in 1 mm3 of blood.
Express your answer in standard form.
(1)
Answer ........................................ . . . . . . . . . . . . . . . . . . . . . .
(b) Which of the following statements about the structure of haemoglobin
are correct?
1. It is a fibrous protein
2. It has quaternary structure
3. It contains a non‑protein haem group
(1)
A 1 only
B 3 only
C 1 and 2 only
D 2 and 3 only
4
*P78384A0432*
