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HESI A2 Vocabulary & General Knowledge Study Guide – 80 Practice Questions with Answers

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Boost your score on the HESI A2 Vocabulary and General Knowledge section with this focused study guide featuring 80 exam-style practice questions. Covers essential medical terminology, commonly tested vocabulary, and general language skills needed for success on the HESI Admission Assessment Exam. Includes accurate answers and clear explanations—ideal for nursing school entrance exam prep.

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HESI A2 Vocabulary and General Knowledge Practice
Exam 2025 - 80 Unique Questions




Comprehensive Study Guide for Nursing School Applicants

Includes 80 Unique Practice Questions with Detailed Answer Key
Covers Medical Terminology, Healthcare Vocabulary, Synonyms, Antonyms, and
General Nursing Knowledge

Updated for the 2025 HESI A2 Exam


Contents

1 Instructions 2

2 Vocabulary and General Knowledge Practice Questions (80 Questions) 2

3 Answer Key with Explanations 12




1

, 1 Instructions
This practice exam prepares you for the Vocabulary and General Knowledge section of
the HESI Admission Assessment (A2) Exam 2025, a nursing school entrance requirement.
It includes 80 multiple-choice questions covering medical terminology, healthcare-related
vocabulary, synonyms, antonyms, and general knowledge relevant to nursing. Select the
best answer from the four options provided. An answer key with explanations is included.

• Time Limit: Approximately 50–60 minutes, reflecting HESI A2 Vocabulary sec-
tion pacing.

• Materials: No calculator required.

• Scoring: Each question is worth 1 point. No penalty for incorrect answers.


2 Vocabulary and General Knowledge Practice Ques-
tions (80 Questions)
1. What is the meaning of "cyanosis"?
a) Chest pain
b) Blue skin discoloration
c) Rapid heartbeat
d) Fever
Answer: b) Cyanosis refers to blue skin due to low oxygen.

2. What is a synonym for "acute"?
a) Chronic
b) Sudden
c) Mild
d) Stable
Answer: b) Acute means sudden or severe.

3. What does the prefix "hypo-" mean in medical terms?
a) Above
b) Below
c) Normal
d) Beside
Answer: b) Hypo- means below or deficient.

4. What is the meaning of "ambulate"?
a) Sleep
b) Walk
c) Eat
d) Speak
Answer: b) Ambulate means to walk or move about.

5. What is an antonym for "benign"?
a) Harmless
b) Malignant

2

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