NR 565 - ADVANCED
PHARMACOLOGY MIDTERM –
CHAMBERLAIN EXAM WITH
CORRECT ANSWERS 2025
During what trimester is a pregnant woman most at risk
for adverse drug reactions with potential long term
consequences? correct answers >> 1st trimester
(fetus most at risk d/t rapid growth)
What is BEERS criteria? correct answers >>
Recommendations of medications inappropriate for
elderly (65 and older), prescriber ultimately decides
What is the CYP450 (cytochrome P450) correct
answers >> liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and
create drug-drug interactions
CYP450 inducers correct answers >> Speed up
metabolism of drugs (drug is cleared faster), drug has
lesser effect (decrease blood levels of drug), elevate
CYP450 enzymes
GRADED A+
,CYP450 inducers pneumonic correct answers >>
"Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names correct answers >>
Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital,
sulfonylureas
CYP450 inhibitors correct answers >> inhibit
metabolism, increase blood levels of medications
CYP450 pneumonic correct answers >> "VISA credit
card debt INHIBITS spending on designers like CK to look
GQ"
CYP450 inhibitors drug names correct answers >>
Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact
pharmacodynamics and pharmacokinetic properties of
drugs? correct answers >> increase glomerular
filtration rate leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
GRADED A+
,increase drug absorption
Examples of medications that can be teratogenic
correct answers >> Antiepileptic drugs, antimicrobials
such as tetracyclines and fluoroquinolones, vitamin A in
large doses, some anticoagulants, and hormonal
medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different
in neonates? correct answers >> slow and erratic
due to low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased
in infancy? correct answers >> delayed gastric
emptying
Some medications that should be avoided in the pediatric
patient? correct answers >> glucocorticoids,
discoloration of developing teeth with tetracyclines, and
kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration
patient education? correct answers >> dosage size
and timing
route and technique of administration
duration of treatment
GRADED A+
, drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at
higher risk for adverse drug reactions? correct
answers >> reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g.,
digoxin)
increased individual variation secondary to altered
pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
How can healthcare providers decrease likelihood of an
elderly patient experiencing an adverse drug reaction?
correct answers >> obtaining a thorough drug history
that includes over-the-counter medications
considering pharmacokinetic and pharmacodynamics
changes due to age
GRADED A+
PHARMACOLOGY MIDTERM –
CHAMBERLAIN EXAM WITH
CORRECT ANSWERS 2025
During what trimester is a pregnant woman most at risk
for adverse drug reactions with potential long term
consequences? correct answers >> 1st trimester
(fetus most at risk d/t rapid growth)
What is BEERS criteria? correct answers >>
Recommendations of medications inappropriate for
elderly (65 and older), prescriber ultimately decides
What is the CYP450 (cytochrome P450) correct
answers >> liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and
create drug-drug interactions
CYP450 inducers correct answers >> Speed up
metabolism of drugs (drug is cleared faster), drug has
lesser effect (decrease blood levels of drug), elevate
CYP450 enzymes
GRADED A+
,CYP450 inducers pneumonic correct answers >>
"Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names correct answers >>
Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital,
sulfonylureas
CYP450 inhibitors correct answers >> inhibit
metabolism, increase blood levels of medications
CYP450 pneumonic correct answers >> "VISA credit
card debt INHIBITS spending on designers like CK to look
GQ"
CYP450 inhibitors drug names correct answers >>
Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact
pharmacodynamics and pharmacokinetic properties of
drugs? correct answers >> increase glomerular
filtration rate leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
GRADED A+
,increase drug absorption
Examples of medications that can be teratogenic
correct answers >> Antiepileptic drugs, antimicrobials
such as tetracyclines and fluoroquinolones, vitamin A in
large doses, some anticoagulants, and hormonal
medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different
in neonates? correct answers >> slow and erratic
due to low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased
in infancy? correct answers >> delayed gastric
emptying
Some medications that should be avoided in the pediatric
patient? correct answers >> glucocorticoids,
discoloration of developing teeth with tetracyclines, and
kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration
patient education? correct answers >> dosage size
and timing
route and technique of administration
duration of treatment
GRADED A+
, drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at
higher risk for adverse drug reactions? correct
answers >> reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g.,
digoxin)
increased individual variation secondary to altered
pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
How can healthcare providers decrease likelihood of an
elderly patient experiencing an adverse drug reaction?
correct answers >> obtaining a thorough drug history
that includes over-the-counter medications
considering pharmacokinetic and pharmacodynamics
changes due to age
GRADED A+
