,Chapter 01: Cellular Biology
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Huether & McCance: Understanding Pathophysiology, 6th Edition
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MULTIPLElCHOICE
1. Alstudentlislobservinglalcelllunderlthelmicroscope.lItlislobservedltolhavelsupercoiledlDNAlwithl
histones.lWhichloflthelfollowinglwouldlalsolbelobservedlbylthelstudent?
a. Alsinglelcircularlchromosome
b. Alnucleus
c. Free-floatinglnuclearlmaterial
d. Nolorganelles
ANS:l B
Thelcellldescribedlislaleukaryoticlcell,lsolitlhaslhistoneslandlalsupercoiledlDNAlwithinlitslnucleus;l
thus,lthelnucleuslshouldlbelobserved.lAlsinglelcircularlchromosomelcalledlalprokaryotelcontainslf
ree-floatinglnuclearlmateriallbutlhaslnolorganelles.
REF:lp.l2
2. Alnurselislinstructinglthelstafflaboutlcellularlfunctions.lWhichlcellularlfunctionlislthelnurseldescr
ibinglwhenlanlisolatedlcelllabsorbsloxygenlandluseslitltoltransformlnutrientsltolenergy?
a. Metaboliclabsorption
b. Communication
c. Secretion
d. Respiration
ANS:lD
Thelcell’slabilityltolabsorbloxygenlislreferredltolaslrespirationlwhilelitslcommunicationlabilitylinvolves
lmaintenanceloflalsteadyldynamiclstate,lmetaboliclabsorptionlprovideslnutrition,landlsecretionlallowslf
orlthelsynthesizingloflnewlsubstances.
REF:lp.l2
3. AleukaryoticlcelllislundergoinglDNAlreplication.lInlwhichlregionloflthelcelllwouldlmostloflthelg
eneticlinformationlbelcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleuslCytoplasm
ANS:lC
Thelregionloflthelcelllthatlcontainslgeneticlmaterial,lincludinglallargelamountloflribonucleiclacid,l
mostloflthelDNA,landlDNA-
bindinglproteins,lislthelnucleolus,lwhichlisllocatedlwithinlthelcell’slnucleus.lMitochondrialislasso
ciatedlwithlcellularlrespiration,lwhilelribosomeslarelinvolvedlwithlproteinlmanufacturing.lCytopl
asmlislalfluidlfillinglthatlislalcomponentloflthelcell.
REF:lp.l2
, 4. Whichloflthelfollowinglcanlremovelproteinslattachedltolthelcell’slbilayerlbyldissolvinglthellaye
rlitself?
a. Peripherallmembranelproteins
b. Integrallmembranelproteins
c. Glycoproteins
d. Cellladhesionlmolecules
ANS:lB
Proteinsldirectlylattachedltolthelmembranelbilayerlcanlbelremovedlbylthelactionloflintegrallmembr
anelproteinslthatldissolvelthelbilayer.lPeripherallmembranelproteinslresidelatlthelsurfacelwhilelcel
lladhesionlmoleculeslarelonltheloutsideloflthelmembrane.lGlycoproteinlmarkslcellslandldoeslnotlfl
oat.
REF:lp.l7
5. Whichloflthelfollowinglcanlbindltolplasmalmembranelreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicllipids
d. Ligands
ANS:lD
Ligandslarelthelonlylspecificlmoleculeslthatlcanlbindlwithlreceptorslonlthelcelllmembrane.
REF:lp.l9
6. Alnurselislreviewinglalreportlfromlalpatientlwithlmetastaticlcancer.lWhatlalternationlinlthelextra
cellularlmatrixlwouldls uNp p oRr t lt hIe ldG
iagnBo.
siC
slofM
metastaticlcancer?
a. Decreasedlfibronectin
U lSlN lT O
b. Increasedlcollagen
c. Decreasedlelastin
d. Increasedlglycoproteins
ANS:lA
Onlylalreducedlamountloflfibronectinlislfoundlinlsomeltypesloflcancerouslcells,lallowinglthemltoltr
avellorlmetastasize.
REF:lp.l10
7. Whichlformloflcelllcommunicationlislusedltolrelateltolotherlcellslinldirectlphysicallcontact?
a. Cellljunction
b. Gapljunction
c. Desmosome
d. Tightljunction
ANS:lA
Cellljunctionslholdlcellsltogetherlandlpermitlmoleculesltolpasslfromlcellltolcell.
Gapljunctionslallowlforlcellularlcommunicationlbetweenlcells.lNeitherldesmosomeslnorltightljunction
slarelassociatedlwithlcellularlcommunication.
REF:lp.l11