ASCP Recalls 2025 Exam Questions and
Verified Answers
FFP used for - Multiple coagulation deficiencies
Factor XI deficiency
Cryoprecipitate used for - Replace fibrinogen loss due to DIC
Massive bleeding
Dysfibrinogenemia with active bleeding
Plateletpheresis preparation steps - Light spin (remove RBC)
Heavy spin (spin down PLT and WBC)
Supernatant goes into bag for freezing (FFP)
Remaining plasma, platelets, and WBC = platelets
Irradiated blood prevents - GVHD
Also used for cancer patients, or patients who are immunocompromised
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Leukocyte reduced blood prevents - Febrile nonhemolytic transfusion reactions
(FNHTRs)
Blood generally kept at what temperature? - 1-10C
Platelets and granulocytes kept at what temperature? - 20-24C
Platelets usually kept on agitator to ensure that the platelets are continuously oxygenated
ACD, CPD, CPD2 expiration - 21 days
CPDA-1 expiration - 35 days
Rouleaux resolution - Saline wash and repeat
Common IgM antibodies in blood bank (Cold) - anti-I, H, M, N, P1, Lea, Leb
Common IgG antibodies in blood bank (Warm) - anti-D, C, c, E, e, M (some), K, k, Fya,
Fyb, Jka, Jkb
Antibodies enhanced by enzyme panel - RhIp Lewis the Kidd
Rh, I, Lea, Leb, Jka, Jkb
Overproduction of IgM associated with - Waldenstrom's Primary Macroglobulinemia
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Overproduction of IgG associated with - Multiple Myeloma
Serum calcitonin elevated in - Medullary carcinoma of thryroid
Normal myeloid:erythroid ratio - 2:1 to 4:1
Centromere ANA pattern - CREST syndrome
Homogeneous or speckled ANA pattern - SLE
Speckeled ANA pattern - RA or Sjorgen's
Measurement of sodium/chloride in sweat is useful test for - Cystic Fibrosis
Analytes increased due to delay in centrifugation - AST, ALT, Potassium, Creatinine
Analytes decreased due to delay in centrifugation - Glucose, ionized calcium,
bicarbonate, folate
Reducing sugars include - Lactose, glucose, ribose
Incorporation of sulfamethoxazole and trimethoprim in culture media enhance recovery
of - Strep. pyogenes
Longer staining times associated with which type of smear - Bone marrow smear
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Dosage associated with homozygous or heterozygous cells - Homozygous
Confirmatory test for syphilis - FTA-ABS (fluorescent treponemal antibody absorption
test)
VRDL and RPR are utilize which type of methodology - Flocculation
Mycobacterium species positive for nitrate reduction - Mycobacterium tuberculosis
Measles (rubella), mumps, polio vaccine deferral time period - 2 weeks
Burkitt's lymphoma - 8:14 translocation; associated with EBV; "starry sky" appearance
on histology
Hodgkin Lymphoma (HL) - is a malignant lymphoma
Reed Sternberg cells are the hallmark of HL. Enlarged, painless lymph node in the neck
(often the first sign of HL).
A defective clot retraction might be caused by - Lack of defect of platelet receptor IIb/IIIa
German measles vaccine deferral time period - 4 weeks
This protozoa can be routinely cultured - Acanthamoeba spp.
Aspirin prevent synthesis of - Thromboxane A2
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