Clinical Chemistry
Clinical Chemistry Comprehensive Exam
2025
Preferred anticoagulant for glucose testing - Sodium fluoride
Maximum allowable time before centrifugation for serum specimens - 2 hours
Analyte falsely elevated by hemolyzed specimen - Potassium
Law relating absorbance to concentration in spectrophotometry - Beer-Lambert Law
Purpose of a photomultiplier tube in spectrophotometry - Convert light into electrical
energy
Final concentration when 10 mL of a 5 M solution is diluted to 100 mL - 0.5 M
Grams of NaCl needed to prepare 500 mL of a 0.9% NaCl solution - 4.5 g
Hormone primarily regulating sodium reabsorption - Aldosterone
Common cause of hyponatremia - SIADH
Normal reference range for serum potassium - 3.5-5.0 mmol/L
Major end product of protein catabolism - Urea
Clinical Chemistry
, Clinical Chemistry
Analyte showing earliest increase in chronic renal disease - Uric acid
Enzyme deficiency leading to galactosemia - Galactose-1-phosphate uridyltransferase
2-hour post-load glucose indicating diabetes mellitus in OGTT - ≥ 200 mg/dL
Lipoprotein referred to as 'bad cholesterol' - LDL
Characteristic finding in multiple myeloma - Elevated Gamma globulin
Marker of inflammation - CRP
Enzyme most specific for liver injury - ALT
Conjugated hyperbilirubinemia suggests - Biliary obstruction
Best test to assess synthetic liver function - Albumin
Enzyme that rises first in myocardial infarction - CK-MB
Condition where ALP is elevated - Obstructive jaundice
Enzyme used to assess pancreatitis - Amylase
Elevated LDH with high LDH-1 suggests - A. Liver damage, B. Myocardial infarction, C.
Muscle injury, D. Renal failure
Clinical Chemistry
Clinical Chemistry Comprehensive Exam
2025
Preferred anticoagulant for glucose testing - Sodium fluoride
Maximum allowable time before centrifugation for serum specimens - 2 hours
Analyte falsely elevated by hemolyzed specimen - Potassium
Law relating absorbance to concentration in spectrophotometry - Beer-Lambert Law
Purpose of a photomultiplier tube in spectrophotometry - Convert light into electrical
energy
Final concentration when 10 mL of a 5 M solution is diluted to 100 mL - 0.5 M
Grams of NaCl needed to prepare 500 mL of a 0.9% NaCl solution - 4.5 g
Hormone primarily regulating sodium reabsorption - Aldosterone
Common cause of hyponatremia - SIADH
Normal reference range for serum potassium - 3.5-5.0 mmol/L
Major end product of protein catabolism - Urea
Clinical Chemistry
, Clinical Chemistry
Analyte showing earliest increase in chronic renal disease - Uric acid
Enzyme deficiency leading to galactosemia - Galactose-1-phosphate uridyltransferase
2-hour post-load glucose indicating diabetes mellitus in OGTT - ≥ 200 mg/dL
Lipoprotein referred to as 'bad cholesterol' - LDL
Characteristic finding in multiple myeloma - Elevated Gamma globulin
Marker of inflammation - CRP
Enzyme most specific for liver injury - ALT
Conjugated hyperbilirubinemia suggests - Biliary obstruction
Best test to assess synthetic liver function - Albumin
Enzyme that rises first in myocardial infarction - CK-MB
Condition where ALP is elevated - Obstructive jaundice
Enzyme used to assess pancreatitis - Amylase
Elevated LDH with high LDH-1 suggests - A. Liver damage, B. Myocardial infarction, C.
Muscle injury, D. Renal failure
Clinical Chemistry
