verified answers
2hPG Ans✓✓✓ -2-hour plasma glucose in 75g oral glucose tolerance
PG-Plasma glucose can be drawn at time of the day
(+) PG test must be confirmed with another test for diagnosis if that is
your only available test
A1C-Glycosylated hemoglobin Ans✓✓✓ permanent binding of glucose
to hemoglobin molecule in a 150 day lifespan
ABCDES of Diabetes Care Ans✓✓✓
ACE-inhibitor or ARB (angiotensin receptor blocker) doses for vascular
protection in T2DM ? Ans✓✓✓ perindopril 8 mg once daily
ramipril 10 mg once daily
telmisartan 80 mg once daily
ASA should not routinely be used for the primary prevention of
cardiovascular disease in type 2 DM Ans✓✓✓ ASA may be used for
secondary prevention.
,Assess risk ANNUALLY if: Ans✓✓✓ ·Family history (First-degree relative
with Type 2 DM)
High risk populations (Non-white, low socioeconomic status)
History of GDM/prediabetes
Cardiovascular risk factors
Presence of end organ damage associated with diabetes (neuropathy,
nephropathy, retinopathy)
Other conditions and medications associated with diabetes
At diagnosis of type 2 diabetes Ans✓✓✓ Start healthy behaviour
interventions (nutritional therapy, weight management, physical
activity
+ - metformin
BP targets in diabetes Ans✓✓✓ BP <130/80 mmHg
, If on treatment, assess for risk of falls
Canagliflozin: avoid in patients Ans✓✓✓ with risk factors for lower
limb amputations.
Cholesterol targets in diabetes Ans✓✓✓ LDL-C <2.0 mmol/L
Diabetes Canada Criteria Ans✓✓✓ FPG > 7mmol/L or
A1C > 6.5% or
2hPG in a 75 g OGTT > 11.1 mmol/L or
Random PG > 11.1 mmol/L
Diabetes: Key Differences Ans✓✓✓ Environmental and genetic
influences
INSULINRESISTANCE
Main driver is CENTRAL VISCERAL OBESITY
Increased release of adipose factors