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• 2025 NU545 Unit 5 Q&A – Pathophysiology with Answers

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• 2025 NU545 Unit 5 Q&A – Pathophysiology with Answers

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1. What is the primary cause of hypercapnia in patients with
chronic obstructive pulmonary disease (COPD)?
A. Increased carbon dioxide production
B. Airway obstruction
C. Pulmonary fibrosis
D. Decreased tidal volume
Answer: B) Airway obstruction
Rationale: In COPD, airway obstruction leads to difficulty in
exhaling CO2, resulting in the accumulation of carbon dioxide in
the bloodstream (hypercapnia).

2. Which of the following is a common cause of hypoxemia?
A. Anemia
B. Asthma
C. Hypertension
D. Diabetes
Answer: B) Asthma
Rationale: Asthma causes bronchoconstriction and inflammation
in the airways, leading to decreased oxygen exchange and
resulting in hypoxemia.

3. A patient with COPD has developed a barrel chest. What does
this physical finding indicate?
A. Emphysema
B. Pneumonia
C. Asthma
D. Acute bronchitis
Answer: A) Emphysema
Rationale: A barrel chest is a physical characteristic seen in
emphysema, a type of COPD. It occurs due to the hyperinflation
of the lungs, which causes the chest to assume a rounded,

,expanded shape.

4. What is a common complication of untreated hyperthyroidism?
A. Heart failure
B. Bradycardia
C. Hypoglycemia
D. Myxedema coma
Answer: A) Heart failure
Rationale: Untreated hyperthyroidism can lead to tachycardia and
increased cardiac workload, which can eventually result in heart
failure.

5. What is a classic symptom of Parkinson’s disease?
A. Muscle rigidity
B. Hypotension
C. Polyuria
D. Weight gain
Answer: A) Muscle rigidity
Rationale: Parkinson’s disease is characterized by symptoms such
as muscle rigidity, tremors, and bradykinesia due to a loss of
dopaminergic neurons in the brain.

6. What is the main cause of type 2 diabetes?
A. Insulin resistance
B. Insulin deficiency
C. Autoimmune destruction of beta cells
D. Excessive glucagon secretion
Answer: A) Insulin resistance
Rationale: Type 2 diabetes is primarily caused by insulin
resistance, where the body’s cells do not respond effectively to
insulin, leading to elevated blood glucose levels.

7. A patient has been diagnosed with tuberculosis (TB). Which of

, the following is the most common symptom?
A. Night sweats
B. Joint pain
C. Hematuria
D. Abdominal pain
Answer: A) Night sweats
Rationale: Night sweats are a classic symptom of tuberculosis,
along with cough and weight loss.

8. Which of the following lab findings is typically seen in a patient
with acute renal failure (ARF)?
A. Increased serum creatinine
B. Decreased serum potassium
C. Decreased blood urea nitrogen (BUN)
D. Decreased urine output (oliguria)
Answer: A) Increased serum creatinine
Rationale: In acute renal failure, the kidneys' ability to excrete
waste products diminishes, leading to an increase in serum
creatinine levels.

9. A nurse is caring for a patient with pneumonia. Which of the
following is a common sign of pneumonia?
A. Cough with sputum production
B. Sudden weight gain
C. Seizures
D. Hemoptysis without cough
Answer: A) Cough with sputum production
Rationale: Pneumonia typically presents with symptoms such as a
productive cough with purulent sputum, fever, and difficulty
breathing due to inflammation in the lungs.

10. Which of the following is the most likely cause of anaphylactic
shock?

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