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• Advanced Pathophysiology Midterm NURS Exam Study Guide

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• Advanced Pathophysiology Midterm NURS Exam Study Guide

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1. A patient with a diagnosis of systemic lupus erythematosus
(SLE) is at increased risk for which of the following?
A. Infection
B. Weight loss
C. Hyperthyroidism
D. Stroke
Answer: A) Infection
Rationale: SLE is an autoimmune disorder that affects the immune
system, leaving the patient at higher risk for infections due to
immunosuppressive therapy and the disease itself.

2. Which of the following is the most common cause of stroke?
A. Aneurysm rupture
B. Ischemia due to a clot
C. Brain tumor
D. Hypertension
Answer: B) Ischemia due to a clot
Rationale: Ischemic strokes are the most common type of stroke
and occur when a clot blocks blood flow to the brain.

3. A patient with diabetes mellitus presents with polyuria,
polydipsia, and weight loss. What condition might these
symptoms indicate?
A. Diabetic ketoacidosis (DKA)
B. Hyperosmolar hyperglycemic state (HHS)
C. Hypoglycemia
D. Hypertension
Answer: A) Diabetic ketoacidosis (DKA)
Rationale: DKA occurs when insulin deficiency causes increased
glucose production and fat breakdown, leading to ketosis and
elevated blood glucose levels, which cause symptoms like

,polyuria, polydipsia, and weight loss.

4. Which of the following is the primary treatment goal for a
patient with acute myocardial infarction (MI)?
A. Increase fluid intake
B. Reduce heart rate and oxygen demand
C. Prevent deep vein thrombosis
D. Enhance gastrointestinal function
Answer: B) Reduce heart rate and oxygen demand
Rationale: The primary goal in managing MI is to reduce the
heart's workload by decreasing heart rate and oxygen demand to
prevent further damage to the heart muscle.

5. What is the primary cause of hypercapnia in patients with
chronic obstructive pulmonary disease (COPD)?
A. Increased carbon dioxide production
B. Airway obstruction
C. Pulmonary fibrosis
D. Decreased tidal volume
Answer: B) Airway obstruction
Rationale: In COPD, airway obstruction leads to difficulty in
exhaling CO2, resulting in the accumulation of carbon dioxide in
the bloodstream (hypercapnia).

6. A nurse is caring for a patient with rheumatoid arthritis. Which
of the following is a common manifestation of this condition?
A. Symmetrical joint pain and swelling
B. Morning dizziness and fatigue
C. Unilateral leg swelling
D. Chest pain
Answer: A) Symmetrical joint pain and swelling
Rationale: Rheumatoid arthritis typically causes symmetrical joint
pain, stiffness, and swelling, particularly in the hands and feet.

, 7. What is the primary cause of osteoarthritis?
A. Autoimmune reaction
B. Wear and tear on the joints
C. Bacterial infection
D. Vitamin D deficiency
Answer: B) Wear and tear on the joints
Rationale: Osteoarthritis is primarily caused by the degeneration
of cartilage due to repetitive use or aging, leading to joint pain
and stiffness.

8. Which of the following is a primary complication of untreated
hypertension?
A. Diabetes
B. Stroke
C. Asthma
D. Hyperthyroidism
Answer: B) Stroke
Rationale: Untreated hypertension can cause damage to blood
vessels, increasing the risk of a stroke due to the development of
atherosclerosis or rupture of a weakened vessel.

9. Which of the following is a typical sign of hypoglycemia?
A. Increased thirst
B. Shaking and sweating
C. Increased urination
D. Elevated blood pressure
Answer: B) Shaking and sweating
Rationale: Hypoglycemia causes symptoms such as shaking,
sweating, and confusion due to the body's response to low blood
sugar levels.

10. What is a common sign of a urinary tract infection (UTI) in

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