AG-ACNP Board Certification exam
2025 Questions and Answers
TIBC - ANSWER✔✔-total iron binding capacity
normal - 250-450
Higher iron binding capacity need mean GREATER need for iron
MCV - ANSWER✔✔-Mean corpuscular volume-average volume or size of a single red
blood cell
Normal: 80-100
<80 - microcytic
80-100 - normocytic
>100 - macrocytic
MCHC - ANSWER✔✔-Mean Corpuscular Hgb Concentration
Normal: 32-36%
< 32% - Hypochromic
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,32-36% - normochromic
> 36% - hyperchromic
Low MCV diseases - ANSWER✔✔-Iron deficiency anemia
Thalassemia
High MCV diseases - ANSWER✔✔-B12 or Folate deficiency
ETOH
Liver failure
Drug effects
Normocyctic anemia diseases - ANSWER✔✔-Anemia of chronic diseases
sickle cell
renal failure
blood loss
hemolysis
iron deficiency anemia - ANSWER✔✔-slow onset, few sx w/ Hct > 30
Low serum ferritin
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,High TIBC
High RDW (red cell distribution width)
Positive Brudzinski's sign - ANSWER✔✔-is flexion of the hips and knees when the neck
is flexed
Likely meningitis!
Syphilis - ANSWER✔✔-4 stages
Primary: usually missed
Secondary: 2-8 weeks later, flu-like sx; GENERALIZED MACULOPAPULAR RASH
(esp on palms & soles)
Latent: asymptomatic > 12 months
Tertiary: 10-30 yrs; CNS involvement, multisystem effects
Dx: VDRL or RPR --> then confirm with TP-PA or FTA-ABS (treponemal test)
Tx: Penicillin G - Primary & Secondary - x1; Latent & Tertiary 3weeks
If allergic --> Doxy or Tetra PO x14d
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, Report to health department
pulseless ventricular tachycardia (VT) defibrillation - ANSWER✔✔-150-200 J on
biphasic and 360 J on a monophasic defibrillator
cerebral perfusion pressure (CPP) calc? - ANSWER✔✔-MAP - ICP
Normal: 60-80
acute muscle strain Tx - ANSWER✔✔-NSAIDS
Cyclobenzaprine (muscle relaxant)
Acute anal fissures tx - ANSWER✔✔-sitz baths, stool softeners, and topical
corticosteroids
Chronic anal fissures tx - ANSWER✔✔-topical nitroglycerin or botulinum toxin
injections
Meningitis - ANSWER✔✔-Acute bacterial meningitis --> medical emergency
Pathogens: Strep pneumoniae, Hemophilus influenzae, Neisseria meningitidis
Sx: Fever, severe HA, n/v, NUCHAL RIGIDITY (stiff neck), photophobia
Positive Kernig's sign: pain and spasms of hamstirng muscles; supine w/ legs and hips
flexed
Positive Brudzinki's sign
COPYRIGHT © 2025 ALL RIGHTS RESERVED
2025 Questions and Answers
TIBC - ANSWER✔✔-total iron binding capacity
normal - 250-450
Higher iron binding capacity need mean GREATER need for iron
MCV - ANSWER✔✔-Mean corpuscular volume-average volume or size of a single red
blood cell
Normal: 80-100
<80 - microcytic
80-100 - normocytic
>100 - macrocytic
MCHC - ANSWER✔✔-Mean Corpuscular Hgb Concentration
Normal: 32-36%
< 32% - Hypochromic
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,32-36% - normochromic
> 36% - hyperchromic
Low MCV diseases - ANSWER✔✔-Iron deficiency anemia
Thalassemia
High MCV diseases - ANSWER✔✔-B12 or Folate deficiency
ETOH
Liver failure
Drug effects
Normocyctic anemia diseases - ANSWER✔✔-Anemia of chronic diseases
sickle cell
renal failure
blood loss
hemolysis
iron deficiency anemia - ANSWER✔✔-slow onset, few sx w/ Hct > 30
Low serum ferritin
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,High TIBC
High RDW (red cell distribution width)
Positive Brudzinski's sign - ANSWER✔✔-is flexion of the hips and knees when the neck
is flexed
Likely meningitis!
Syphilis - ANSWER✔✔-4 stages
Primary: usually missed
Secondary: 2-8 weeks later, flu-like sx; GENERALIZED MACULOPAPULAR RASH
(esp on palms & soles)
Latent: asymptomatic > 12 months
Tertiary: 10-30 yrs; CNS involvement, multisystem effects
Dx: VDRL or RPR --> then confirm with TP-PA or FTA-ABS (treponemal test)
Tx: Penicillin G - Primary & Secondary - x1; Latent & Tertiary 3weeks
If allergic --> Doxy or Tetra PO x14d
COPYRIGHT © 2025 ALL RIGHTS RESERVED
, Report to health department
pulseless ventricular tachycardia (VT) defibrillation - ANSWER✔✔-150-200 J on
biphasic and 360 J on a monophasic defibrillator
cerebral perfusion pressure (CPP) calc? - ANSWER✔✔-MAP - ICP
Normal: 60-80
acute muscle strain Tx - ANSWER✔✔-NSAIDS
Cyclobenzaprine (muscle relaxant)
Acute anal fissures tx - ANSWER✔✔-sitz baths, stool softeners, and topical
corticosteroids
Chronic anal fissures tx - ANSWER✔✔-topical nitroglycerin or botulinum toxin
injections
Meningitis - ANSWER✔✔-Acute bacterial meningitis --> medical emergency
Pathogens: Strep pneumoniae, Hemophilus influenzae, Neisseria meningitidis
Sx: Fever, severe HA, n/v, NUCHAL RIGIDITY (stiff neck), photophobia
Positive Kernig's sign: pain and spasms of hamstirng muscles; supine w/ legs and hips
flexed
Positive Brudzinki's sign
COPYRIGHT © 2025 ALL RIGHTS RESERVED
