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WGU – D115 – Advanced Pathophysiology – Western Governors University – 2025 – Complete Objective Assessment Exam with Verified Answers and Rationales (400 Questions)

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his document includes 400 detailed, verified multiple-choice questions with correct answers and rationales for the WGU D115 Advanced Pathophysiology course. It covers high-yield clinical concepts such as hematologic disorders (e.g., pernicious anemia, hemolytic anemia), cardiovascular syndromes (e.g., Takotsubo cardiomyopathy, Kawasaki disease), renal pathologies (e.g., nephrotic syndrome, vesicoureteral reflux), immune conditions, diabetes-related complications, and more. Designed to match the 2025 Objective Assessment version, this A+-graded material supports exam preparation with rationales to reinforce

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WGU D115 OBJECTIVE ASSESSMENT 2 LATEST VERSIONS 2025
ACTUAL EXAM COMPLETE 400 QUESTIONS AND CORRECT
DETAILED ANSWERS WITH RATIONALES (VERIFIED ANSWERS)
|ALREADY GRADED A+

An advanced practice registered nurse (aprn) assesses a patient with a long
history of infections, mood swings, and gastrointestinal complaints. The
patient complains of increasing fatigue, difficulty walking, and a sore tongue.
Lab results indicate a hemoglobin of 7.8 g/dl.

Which type of anemia should the aprn consider?

A. Hemolytic anemia
B. Sideroblastic anemia
C. Pernicious anemia
D. Iron-deficiency anemia - answer-pernicious anemia

Pernicious anemia is an autoimmune condition that prevents your
body from absorbing vitamin b12.



Is a result of excessive destruction of erythrocytes and may be acquired or
hereditary. Common, acquired forms are autoimmune reaction
(immunohemolytic) and drug-induced hemolysis. - answer-hemolytic anemia



An advanced practice registered nurse (aprn) is evaluating a male patient.
Findings include a painless supraclavicular adenopathy, a nonproductive
cough, fatigue, anorexia, weight loss, fever, night sweats, pruritus, and the
findings of reed-sternberg cells on a lab microscopic exam.

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Which disease should be suspected by the aprn?

A. B-precursor all
B. Acute myeloid leukemia
C. Non-hodgkin lymphoma
D. Hodgkin lymphoma - answer-hodgkin lymphoma

Hodgkin's lymphoma and non-hodgkin's lymphoma are two types of
lymphoma. The main difference between the two is whether you have
a type of cell called reed-sternberg cells. These cells are only present
in people with hodgkin's lymphoma. Non-hodgkin's lymphoma is more
common than hodgkin's lymphoma.



A patient presents to a clinic with complaints of frequent nosebleeds. An
advanced practice registered nurse (aprn) does an assessment and notes
areas of ecchymosis and petechiae. The aprn questions the patient about
current activities and medications and orders lab studies.

Which lab exam should the aprn order for this patient?

A. Lactic acid
B. Platelet count
C. Monocytes
D. Neutrophils - answer-platelet count



A 56-year-old patient presents to an emergency department with acute chest
pain on the day after the funeral of a spouse. Diagnostic results reveal st
elevation and elevated troponins.

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What is the probable diagnosis of these symptoms?

A. Unstable angina
B. Ventricular aneurysm
C. Takotsubo cardiomyopathy (broken heart syndrome)
D. Pulmonary hypertension - answer-takotsubo cardiomyopathy (broken
heart syndrome)



A child presents to a clinic with a fever, conjunctivitis, and a strawberry
tongue. An advanced practice registered nurse (aprn) assesses the patient,
and stage iv kawasaki disease is suspected.

What is the pathological mechanism of this disorder?

A. Constriction of the ductal tissue
B. Obstruction of left ventricular outflow tract
C. Obstruction of blood flow to the vessels and aorta
D. Intimal thickening and stenosis of coronary arteries - answer-intimal
thickening and stenosis of coronary arteries



Nephrotic syndrome - answer-nephrotic syndrome is the excretion of at least
3.5 g of protein (primarily albumin) in the urine per day primarily because of
glomerular injury with increased capillary permeability and loss of membrane
negative charge. The principal signs are hypoproteinemia, hyperlipidemia,
and edema. The liver cannot produce enough protein to adequately
compensate for urinary loss.

Frothy urine, edema,,dark urine and malaise

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A two-year-old child presents to a clinic with acute pyelonephritis for the third
time in four months. An advanced practice registered nurse (aprn) suspects
vesicoureteral reflux and orders a voiding cystourethrograph scan. Results
indicate reflux into dilated ureter or blunting of calyceal fornices.

Which grade should the aprn document?

A. Grade ii
B. Grade iii
C. Grade iv
D. Grade v - answer-grade 3



Grade 1: reflux limited to the ureter

Grade 2: reflux up to the renal pelvis

Grade 3: mild dilatation of ureter and pelvicalyceal system

Grade 4 tortuous ureter with moderate dilatation, blunting of fornices but
preserved papillary impressions

Grade 5 tortuous ureter with severe dilatation of ureter and pelvicalyceal
system, loss of fornices and papillary impressions



An advanced practice registered nurse (aprn) is working with a patient who
has a history of type 1 diabetes and is now experiencing renal failure. The
aprn counsels the patient concerning an increase in the incidence of
hypoglycemia.

Which pathological mechanism contributes to this concern?

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