5/19/25, 12:01 PM GMS 6552 Exam 1 ELABORATED EXAM (A+ GRADED 100% VERIFIED) QUESTIONS & ANSWERS 2025 LATEST!! Flash…
GMS 6552 Exam 1 ELABORATED EXAM (A+
GRADED 100% VERIFIED) QUESTIONS &
ANSWERS 2025 LATEST!!
Save
Terms in this set (114)
Receptors-45%
Enzymes-28%
Hormones-11%
Molecular Drug Targets
Unknown-7%
Ion Channels-5%
DNA-4%
Channel-Linked Produce cellular effects in milliseconds
(Ionotropic) Receptors Nicotinic ACh receptor
Effects happen in seconds
GPCRs
Muscarinic ACh receptor
Effects happen in minutes
Kinase-linked receptors
Insulin receptor
Receptors linked to gene Effects happen in hours
transcription Estrogen receptor
Heterotrimeric G proteins alpha, beta and gamma subunits
More than 800 receptors
7 transmembrane domains
GPCR Components N and C termini
Conformationally flexible
Constitutively active
Hormones, neurotransmitters, chemokine, ions,
GPCR Ligands
amino acids, peptides
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, 5/19/25, 12:01 PM GMS 6552 Exam 1 ELABORATED EXAM (A+ GRADED 100% VERIFIED) QUESTIONS & ANSWERS 2025 LATEST!! Flash…
a-20
Gas- increases AC
G-proteins Gai - decreases AC
Gaq - increases PLC
b(6)y(12)
Means of amplifying the signal
Why use G proteins
G proteins can regulate more than one effector
Phosphorylase Kinase (glycogen breakdown)
CREB (gene transcription)
PKA L-type Ca channels (heart contraction)
Pyruvate Kinase (glycolysis)
Hormone Sensitive Lipase (triglyceride breakdown)
Kinase-linked receptor No second messenger
signaling
Receptors associated with cytosolic kinases
Protein kinase-linked
Receptor tyrosine kinases
receptors
Receptor serine/threonine kinases
Ligands:
Prolactin
Receptors associated
GH
with cytosolic kinases
Interferons
Cytokines
Receptor tyrosine kinases (RTKs) consist of an
extracellular ligand
binding and dimerization domain, a single
Receptor tyrosine kinases hydrophobic
transmembrane a-helix and a cytosolic domain with
intrinsic
tyrosine kinase activity
Single transmembrane spanning proteins that
dimerize when ligand binds (EGF receptor, PGDF
Two types of RTKs receptor)
Covalently linked dimers (insulin receptor, IGF-1
receptor)
phosphorylate multiple proteins which regulate a
PKB/Akt
wide variety of intracellular events
https://quizlet.com/1045675486/gms-6552-exam-1-elaborated-exam-a-graded-100-verified-questions-answers-2025-latest-flash-cards/?new 2/13
GMS 6552 Exam 1 ELABORATED EXAM (A+
GRADED 100% VERIFIED) QUESTIONS &
ANSWERS 2025 LATEST!!
Save
Terms in this set (114)
Receptors-45%
Enzymes-28%
Hormones-11%
Molecular Drug Targets
Unknown-7%
Ion Channels-5%
DNA-4%
Channel-Linked Produce cellular effects in milliseconds
(Ionotropic) Receptors Nicotinic ACh receptor
Effects happen in seconds
GPCRs
Muscarinic ACh receptor
Effects happen in minutes
Kinase-linked receptors
Insulin receptor
Receptors linked to gene Effects happen in hours
transcription Estrogen receptor
Heterotrimeric G proteins alpha, beta and gamma subunits
More than 800 receptors
7 transmembrane domains
GPCR Components N and C termini
Conformationally flexible
Constitutively active
Hormones, neurotransmitters, chemokine, ions,
GPCR Ligands
amino acids, peptides
https://quizlet.com/1045675486/gms-6552-exam-1-elaborated-exam-a-graded-100-verified-questions-answers-2025-latest-flash-cards/?new 1/13
, 5/19/25, 12:01 PM GMS 6552 Exam 1 ELABORATED EXAM (A+ GRADED 100% VERIFIED) QUESTIONS & ANSWERS 2025 LATEST!! Flash…
a-20
Gas- increases AC
G-proteins Gai - decreases AC
Gaq - increases PLC
b(6)y(12)
Means of amplifying the signal
Why use G proteins
G proteins can regulate more than one effector
Phosphorylase Kinase (glycogen breakdown)
CREB (gene transcription)
PKA L-type Ca channels (heart contraction)
Pyruvate Kinase (glycolysis)
Hormone Sensitive Lipase (triglyceride breakdown)
Kinase-linked receptor No second messenger
signaling
Receptors associated with cytosolic kinases
Protein kinase-linked
Receptor tyrosine kinases
receptors
Receptor serine/threonine kinases
Ligands:
Prolactin
Receptors associated
GH
with cytosolic kinases
Interferons
Cytokines
Receptor tyrosine kinases (RTKs) consist of an
extracellular ligand
binding and dimerization domain, a single
Receptor tyrosine kinases hydrophobic
transmembrane a-helix and a cytosolic domain with
intrinsic
tyrosine kinase activity
Single transmembrane spanning proteins that
dimerize when ligand binds (EGF receptor, PGDF
Two types of RTKs receptor)
Covalently linked dimers (insulin receptor, IGF-1
receptor)
phosphorylate multiple proteins which regulate a
PKB/Akt
wide variety of intracellular events
https://quizlet.com/1045675486/gms-6552-exam-1-elaborated-exam-a-graded-100-verified-questions-answers-2025-latest-flash-cards/?new 2/13
