Prostate Cancer Exam Questions with Correct Answers 100% Verified| Guaranteed Success
African Americans and men who have first degree relatives diagnosed before the age of 60
should start annual screenings at what age? 45
List the Gleason Scores for prostate cancer 2-4 well differentiated
5-6 moderately differentiated
7-10 poorly differentiated
Poorly differentiated tumors grow ______(poor prognosis), while well differentiated tumors
grow ______(better prognosis). rapidly, slowly
What is the MOA for LHRH agonist? Decreases the release of LH and FSH which results in
decrease level of testosterone
Name the LHRH agonist Leuprolide
What are the brand names and formulations for leuprolide? Lupron ®(Depot), Eligard®(SQ),
Viadur® (Implant)
How do you give Eligard? once daily
How to you give Lupron? once every 4, 12 , 16 weeks, or 24 weeks
How do you give Viadur? In the upper arm, delivered over 12 months
What are the monitoring parameters for leuprolide? Serum testosterone (less 20ng/dl is
goal)
, PSA every 3 to 6 months
DEXA scans at baseline every one to two years
Common side effect for leuprolide disease flare during 1st week of tx, because of
testosterone surge, hot flashes, gynecomastia, impotence, decreased libido, osteoporosis, bone
pain, elevated triglycerides, injections site pain
Supportive care for leuproide Calcium 1,200 mg in 2 divided doses
Vitamin D 800-1000 IU for prostate cancer (usually 400-800 in normal pts)
Brand name for Goserelin Zoladex (implant) dosed every 4 or 12 weeks
Name the Antiandrogens Flutamide
Bicalutamide
Nilutamide
Flutamide Eulexin (250mg tid)
Bicalutamide Casodex (50mg po qd)
Nalutamide Nilandron (300mg po qd 1 month; 150mg qd)
Side effects of antiandrogens Photosensitivity, hot flashes, impotence, decreased libido,
Diarrhea
Which antiandrogen causes the most diarrhea flutamide & bicalutamide
African Americans and men who have first degree relatives diagnosed before the age of 60
should start annual screenings at what age? 45
List the Gleason Scores for prostate cancer 2-4 well differentiated
5-6 moderately differentiated
7-10 poorly differentiated
Poorly differentiated tumors grow ______(poor prognosis), while well differentiated tumors
grow ______(better prognosis). rapidly, slowly
What is the MOA for LHRH agonist? Decreases the release of LH and FSH which results in
decrease level of testosterone
Name the LHRH agonist Leuprolide
What are the brand names and formulations for leuprolide? Lupron ®(Depot), Eligard®(SQ),
Viadur® (Implant)
How do you give Eligard? once daily
How to you give Lupron? once every 4, 12 , 16 weeks, or 24 weeks
How do you give Viadur? In the upper arm, delivered over 12 months
What are the monitoring parameters for leuprolide? Serum testosterone (less 20ng/dl is
goal)
, PSA every 3 to 6 months
DEXA scans at baseline every one to two years
Common side effect for leuprolide disease flare during 1st week of tx, because of
testosterone surge, hot flashes, gynecomastia, impotence, decreased libido, osteoporosis, bone
pain, elevated triglycerides, injections site pain
Supportive care for leuproide Calcium 1,200 mg in 2 divided doses
Vitamin D 800-1000 IU for prostate cancer (usually 400-800 in normal pts)
Brand name for Goserelin Zoladex (implant) dosed every 4 or 12 weeks
Name the Antiandrogens Flutamide
Bicalutamide
Nilutamide
Flutamide Eulexin (250mg tid)
Bicalutamide Casodex (50mg po qd)
Nalutamide Nilandron (300mg po qd 1 month; 150mg qd)
Side effects of antiandrogens Photosensitivity, hot flashes, impotence, decreased libido,
Diarrhea
Which antiandrogen causes the most diarrhea flutamide & bicalutamide
