Exam Questions Fully Solved.
Pathophysiology - Answer is the study of functional or physiological change in the body that
result from a disease process
Pharmacology - Answer is the study of the biological effects of chemicals on living organisms
Ischemia - Answer is cell damage d/t deficit of O2
Necrosis - Answer is dying cells causing further damage d/t cellular disintegration
Homeostasis - Answer is the maintenance of a relatively stable internal environment
regardless of external changes
Body is designed to maintain this table environment
Any deviation from this normal state is disease
Etiology - Answer are the causative factors in a particular disease
Therapeutic class - Answer is based on therapeutic usefulness in treating particular diseases or
disorders (broad)
Pharmacologic class - Answer is based on the way a drug works at the molecular, tissue, or
body system level. Addresses a drug's mechanism of action (specific)
Mechanism of action - Answer is how a drug produces its physiological effect in the body
Pharmacokinetics - Answer is the study of drug movement throughout the body; explained
through absorption, distribution, metabolism, excretion
Absorption - Answer is movement from site of administration, across body membranes, to
circulating fluids. Primary pharmacokinetic factor determining length of time for drug to
produce effect
, Metabolism (biotransformation) - Answer is the chemical conversion of a drug so it can be
easily removed from the body. **Liver is the primary site
Excretion - Answer is how drug gets out of the body. Primary site of excretion of drugs is the
kidneys
What are the divisions of the PNS? - Answer autonomic nervous system and somatic nervous
system
What are the primary neurotransmitters of the ANS? - Answer Catecholamines and
Acetylcholine (Ach)
What do catecholamines primarily act on? - Answer Alpha and Beta receptors
What does Acetylcholine primarily act on? - Answer Nicotinic and Muscarinic receptors
Catecholamines are neurotransmitters of the ... - Answer SYMPATHETIC nervous system
Ach is the neurotransmitter of the... - Answer PARASYMPATHETIC nervous system
The Adrenergic receptor alpha 1 is found... - Answer In all sympathetic target organs except
heart
The Adrenergic receptor alpha 2 is found... - Answer At presynaptic adrenergic neuron
terminals
*inhibits release of norepinepherine
The Adrenergic receptor beta 1 is found... - Answer in the cardiac tissue
-increases the heart rate and increase the
heart's strength of contraction or
contractility.