Test Bank For Abrams' Clinical Drug Therapy: Rationales for Nursing Practice 13th Edition by Geralyn Frandsen, SANDRA PENNINGTON|All Chapters |Latest Version 2025 A+

Test Bank For Abrams’ Clinical Drug Therapy R
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ationales for Nursing Practice 13th Edition (Vers
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ion 2024/2025) Geralyn Frandsen
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Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
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the expected effect for this prescription?
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A. Curative effect on symptoms b6 b6 b6


B. Systemic effect on symptoms b6 b6 b6


C. Local effect on symptoms b6 b6 b6


D. Parenteral effect on symptoms b6 b6 b6




ANS: B b 6


Rationale: Drugs that produce systemic effects are taken into the body, circulated through
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the bloodstream to their sites of action in various body tissues, and eventually eliminated
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from the body. Curative agents are given to cure a disease process. In this case, paroxeti
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ne hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff
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ects, such as sunscreen and local anesthetics, act mainly at the site of application. Paroxet
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ine hydrochloride is not administered parenterally. Parenteral agents are administered sub
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cutaneously, intramuscularly, or intravenously. b6 b6 b6




PTS: 1 REF: p. 3, Introduction OBJ: 1 b6 b6


NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand NOT: Multiple Choice
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2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt Mi s another name for this type o
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b6
.C b6 b6 b6 b6 b6 b6 b6 b6 b6 b6


f medication?
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A. Synthetic drug
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B. Semisynthetic drug b6
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C. Biotechnology drug b6
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D. Prototype drug b6
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ANS: B
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Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their chemic
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al characteristics, more consistent in their effects, and less likely to produce allergic react
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ions. Biotechnology drugs involve manipulating DNA and RNA and recombining genes i
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nto hybrid molecules that can be inserted into living organisms. Prototype drugs are the f
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irst drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 b6 b6 b6


NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: b6Chapter: 1: The Foundation of Pharmacology: Quality and Safety b6 b6 b6 b6 b6 b6 b6 b6


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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3. Which classification applies to morphine?
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A. Central nervous system depressant b6 b6 b6


B. Central nervous system stimulant b6 b6 b6




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C. Anti-inflammatory
D. Antihypertensive
ANS: A b 6


Rationale: Drugs are classified according to their effects on particular body systems, their
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therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
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rvous system depressant and will produce this effect in the client. A central nervous syste
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m stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
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6antihypertensive agent reduces blood pressure. b6 b6 b6 b6




PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
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4. A client is administered amoxicillin. The generic name of this medication belongs to whi
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ch drug group?
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A. Selective serotonin reuptake inhibitors b6 b6 b6


B. Diuretics
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C. Penicillins
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D. ACE inhibitors b6
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ANS: C
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Rationale: The generic name often indicates the drug group (e.g., drugs with generic nam
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es ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medicatio
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ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur
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etics are medications that increase urine output; diuretic is a broad classification, not a ge
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neric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
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not the generic name.
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PTS: 1 REF: p. 3, Drug Names OBJ: 2 b6 b6 b6
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
b6 Chapter: 1: The Foundation of Pharmacology: Quality and Safety b6 b6 b6 b6 b6 b6 b6 b6


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service b6 b6


B. Federal Trade Commission b6 b6


C. Occupational Safety and Health Administration b6 b6 b6 b6


D. Food and Drug Administration b6 b6 b6




b6 ANS: D b 6




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Rationale: The Food and Drug Administration approves drugs for over-the-
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counter availability, including the transfer of drugs from prescription to OTC status, and
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may require clinical trials to determine the safety and effectiveness of OTC use. The Pu
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blic Health Service is regulated by the state to maintain the health of individual citizens
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of the state. The Federal Trade Commission regulates imports and exports throughout the
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nation. The Occupational Safety and Health Administration regulates safety within the wo
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rkplace.

PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: b6 Chapter: 1: The Foundation of Pharmacology: Quality and Safety b6 b6 b6 b6 b6 b6 b6 b6


KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
b 6 NOT: Multiple Choice b6 b6 b 6 b6




6. In the U.S., the administration of anabolic steroids is regulated by which law?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Comprehensive Drug Abuse Prevention and Control Act
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C. The Harrison Narcotic Act b6 b6 b6


D. The Sherley Amendment b6 b6




ANS: B
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b 6
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Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma
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nufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and anaboli
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c steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powe
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rs and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Ac
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t restricted the importation, manufacture, sale, and use of opium, cocaine, marijuana, and
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other drugs that the act d e f i Gn eRd Aa Ds E
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csS
.TTh.eCSOhM
erley Amendment of 1912 prohibited
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6fraudulent claims of drug effectiveness. b6 b6 b6 b6
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PTS: 1 REF:
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p. 4, Prescription and Nonprescription Drugs OBJ: 3
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
b 6 NOT: Multiple Choice b6 b6 b 6 b6




7. A nurse is responsible for maintaining an accurate count and record of the controlled
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substances on the nursing division. This nursing action is regulated by which U.S. law
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or agency?b6


A. The Food, Drug, and Cosmetic Act of 1938
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B. The Public Health Service b6 b6 b6


C. The Drug Enforcement Administration
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D. The Sherley Amendment b6 b6




b6 ANS: C b 6




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