NSG6005 Advanced Pharmacology
Exam 1 2025/2026 Exam Questions and
Answers | 100% Solved
How medication transports through cell - 🧠 ANSWER ✔✔Medication
(agonists) bind to receptors to elicit response
Agonists bind and activate receptor
How medication transports through cell - 🧠 ANSWER ✔✔Antagonists bind
and prevent receptor activation (competitive or noncompetitive inhibition)
How medication transports through cell - 🧠 ANSWER ✔✔Medications may
bind allosterically to another site resulting in an increase or a decrease in
the response to the agonist
How medication transports through a cell - 🧠 ANSWER ✔✔Multiple forms of
the same receptors can exist and interact with medications
How medication transports through a cell - 🧠 ANSWER ✔✔Medications
may be bound to proteins
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PRIVACY STATEMENT. ALL RIGHTS RESERVED
,How medication transports through a cell - 🧠 ANSWER ✔✔Medications
may bind to multiple types of receptors resulting in altered therapeutic
effects and side effects
Ionization - 🧠 ANSWER ✔✔Plays a significant role in absorption,
distribution across membranes, and renal elimination.
Passive diffusion - 🧠 ANSWER ✔✔Being charged is a negative factor
Primary, secondary, and tertiary amines - 🧠 ANSWER ✔✔May take on a
charge to become neutral
Quaternary amines - 🧠 ANSWER ✔✔Always charged
Charged medications - 🧠 ANSWER ✔✔Water soluble and more easily
eliminated by the kidneys
Henderson-Hasselbalch equation - 🧠 ANSWER ✔✔Defines role of PH t
degree of ionization: Log of prontonated=pKa-PH
Most drugs - 🧠 ANSWER ✔✔Weak acids (donate H+)
Weak bases (accept H+)
PH of stomach - 🧠 ANSWER ✔✔Manipulates base or acid of drug
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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PRIVACY STATEMENT. ALL RIGHTS RESERVED
, Urine - 🧠 ANSWER ✔✔Can alter absorption or elimination based on PH
Distribution - 🧠 ANSWER ✔✔Requires adequate blood supply. Drug goes
to areas of high blood flow first. Areas of low blood supply have a slower
delivery
Phase I metabolism - 🧠 ANSWER ✔✔Oxidation, reduction, deamination,
hydrolysis, sulfonation: -OH, -SH, -NH2 added or unmasked.
Oxidation - 🧠 ANSWER ✔✔The combination of a substance with O2
Reduction - 🧠 ANSWER ✔✔The act of reducing
Deamination - 🧠 ANSWER ✔✔Bodily process in which amino groups are
removed from excess proteins. This happens most often in the liver, though
it also occurs in the kidneys.
Hydrolysis - 🧠 ANSWER ✔✔A chemical process in which a molecule of
water is added to a substance.
Sulfonation - 🧠 ANSWER ✔✔An organic reaction in which a hydrogen atom
on an arene is replaced by a sulfonic acid functional group in an
electrophilic aromatic substitution
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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PRIVACY STATEMENT. ALL RIGHTS RESERVED
Exam 1 2025/2026 Exam Questions and
Answers | 100% Solved
How medication transports through cell - 🧠 ANSWER ✔✔Medication
(agonists) bind to receptors to elicit response
Agonists bind and activate receptor
How medication transports through cell - 🧠 ANSWER ✔✔Antagonists bind
and prevent receptor activation (competitive or noncompetitive inhibition)
How medication transports through cell - 🧠 ANSWER ✔✔Medications may
bind allosterically to another site resulting in an increase or a decrease in
the response to the agonist
How medication transports through a cell - 🧠 ANSWER ✔✔Multiple forms of
the same receptors can exist and interact with medications
How medication transports through a cell - 🧠 ANSWER ✔✔Medications
may be bound to proteins
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
1
PRIVACY STATEMENT. ALL RIGHTS RESERVED
,How medication transports through a cell - 🧠 ANSWER ✔✔Medications
may bind to multiple types of receptors resulting in altered therapeutic
effects and side effects
Ionization - 🧠 ANSWER ✔✔Plays a significant role in absorption,
distribution across membranes, and renal elimination.
Passive diffusion - 🧠 ANSWER ✔✔Being charged is a negative factor
Primary, secondary, and tertiary amines - 🧠 ANSWER ✔✔May take on a
charge to become neutral
Quaternary amines - 🧠 ANSWER ✔✔Always charged
Charged medications - 🧠 ANSWER ✔✔Water soluble and more easily
eliminated by the kidneys
Henderson-Hasselbalch equation - 🧠 ANSWER ✔✔Defines role of PH t
degree of ionization: Log of prontonated=pKa-PH
Most drugs - 🧠 ANSWER ✔✔Weak acids (donate H+)
Weak bases (accept H+)
PH of stomach - 🧠 ANSWER ✔✔Manipulates base or acid of drug
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
2
PRIVACY STATEMENT. ALL RIGHTS RESERVED
, Urine - 🧠 ANSWER ✔✔Can alter absorption or elimination based on PH
Distribution - 🧠 ANSWER ✔✔Requires adequate blood supply. Drug goes
to areas of high blood flow first. Areas of low blood supply have a slower
delivery
Phase I metabolism - 🧠 ANSWER ✔✔Oxidation, reduction, deamination,
hydrolysis, sulfonation: -OH, -SH, -NH2 added or unmasked.
Oxidation - 🧠 ANSWER ✔✔The combination of a substance with O2
Reduction - 🧠 ANSWER ✔✔The act of reducing
Deamination - 🧠 ANSWER ✔✔Bodily process in which amino groups are
removed from excess proteins. This happens most often in the liver, though
it also occurs in the kidneys.
Hydrolysis - 🧠 ANSWER ✔✔A chemical process in which a molecule of
water is added to a substance.
Sulfonation - 🧠 ANSWER ✔✔An organic reaction in which a hydrogen atom
on an arene is replaced by a sulfonic acid functional group in an
electrophilic aromatic substitution
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
3
PRIVACY STATEMENT. ALL RIGHTS RESERVED
